Articles

2022

doi: 10.1016/j.leukres.2022.106836

Response to azacitidine in patients with chronic myelomonocytic leukemia according to overlap myelodysplastic/myeloproliferative neoplasms criteria

A. Triguero, B. Xicoy, L. Zamora, MJ. Jiménez, O. García, M. Calabuig, M. Díaz-Beyá, J. Arzuaga, F. Ramos, A. Medina, T. Bernal, C. Talarn, R. Coll, R. Collado, T.Hua Chen, J. Borrás, S. Brunet, I. Marchante, V. Marco, F. López-Cadenas, M. Calbacho, A. Simiele, M. Cortés, MT. Cedena, M. Pedreño, C. Aguilar, C. Pedró, M. Fernández, C. Stoica, JM. Ribera, G. Sanz

2022

doi: 10.1016/j.leukres.2022.106821

Acute leukemia arising from myeloproliferative or myelodysplastic/myeloproliferative neoplasms: A series of 372 patients from the PETHEMA AML registry

Hernández-Boluda JC, Martínez-Cuadrón D, Pereira A, Rodríguez-Veiga R, Boluda B, Gil C, Casal-Marini S, Serrano J, Martínez-López J, Bergua J, Algarra L, Bernal T, López-Lorenzo JL, Colorado M, López A, Tormo M, Sayas MJ, Trigo F, López-Pavía M, Pérez-Simón JA, Lavilla-Rubira E, Rodríguez-Medina C, Rodríguez-Gutiérrez JI, Sanz-Caballer MA, Montesinos P; PETHEMA group.

2022

doi: 10.3390/cancers14081921

Healthcare Resource Utilization among Patients between 60–75 Years with Secondary Acute Myeloid Leukemia Receiving Intensive Chemotherapy Induction: A Spanish Retrospective Observational Study

Solana-Altabella A, Megías-Vericat JE, Ballesta-López O, Boluda B, Cano I, Acuña-Cruz E, Rodríguez-Veiga R, Torres-Miñana L, Sargas C, Sanz MÁ, Borrell-García C, López-Briz E, Poveda-Andrés JL, De la Rubia J, Montesinos P, Martínez-Cuadrón D.

2022

doi: 10.3324/haematol.2021.278645

Characteristics and outcome of patients with core-binding factor acute myeloid leukemia and FLT3-ITD: results from an international collaborative study

Kayser S, Kramer M, Martínez-Cuadrón D, Grenet J, Metzeler KH, Sustkova Z, Luskin MR, Brunner AM, Elliott MA, Gil C, Marini SC, Ráčil Z, Cetkovsky P, Novak J, Perl AE, Platzbecker U, Stölzel F, Ho AD, Thiede C, Stone RM, Röllig C, Montesinos P, Schlenk RF, Levis MJ.

2022

doi: 10.3390/diagnostics12040953

Panel Sequencing for Clinically Oriented Variant Screening and Copy Number Detection in Chronic Lymphocytic Leukemia Patients

báñez M, Such E, Liquori A, Avestisyan G, Andreu R, Vicente A, Macián MJ, Melendez MC, Morote-Faubel M, Asensi P, Lloret MP, Jarque I, Picón I, Pacios A, Donato E, Mas-Ochoa C, Alonso C, Cañigral C, Sempere A, Romero S, Santiago M, Sanz GF, de la Rubia J, Senent L, Luna I.

2022

doi: 10.3390/cancers14081986

Next-Generation DNA Sequencing-Based Gene Panel for Diagnosis and Genetic Risk Stratification in Onco-Hematology

Gargallo P, Molero M, Bilbao C, Stuckey R, Carrillo-Cruz E, Hermosín L, Pérez-López O, Jiménez-Velasco A, Soria E, Lázaro M, Carbonell P, Yáñez Y, Gómez I, Izquierdo-García M, Valero-García J, Ruiz C, Such E, Calabria I.

2022

doi: 10.1038/s41408-022-00668-8

Venetoclax combinations delay the time to deterioration of HRQoL in unfit patients with acute myeloid leukemia

Keith W. Pratz, Panayiotis Panayiotidis, Christian Recher, Xudong Wei, Brian A. Jonas, Pau Montesinos, Vladimir Ivanov, Andre C. Schuh, Courtney D. DiNardo, Jan Novak, Vlatko Pejsa, Don Stevens, Su-Peng Yeh, Inho Kim, Mehmet Turgut, Nicola Fracchiolla, Kazuhito Yamamoto, Yishai Ofran, Andrew H. Wei, Cat N. Bui, Katy Benjamin, Rajesh Kamalakar, Jalaja Potluri, Wellington Mendes, Jacob Devine & Walter Fiedler

2022

doi: 10.1056/NEJMoa2117344

Ivosidenib and Azacitidine in IDH1-Mutated Acute Myeloid Leukemia

Montesinos P, Recher C, Vives S, Zarzycka E, Wang J, Bertani G, Heuser M, Calado RT, Schuh AC, Yeh SP, Daigle SR, Hui J, Pandya SS, Gianolio DA, de Botton S, Döhner H.

2022

doi: 10.1038/s41408-022-00652-2

A simple score to predict early severe infections in patients with newly diagnosed multiple myeloma

Encinas C, Hernandez-Rivas JÁ, Oriol A, Rosiñol L, Blanchard MJ, Bellón JM, García-Sanz R, de la Rubia J, de la Guía AL, Jímenez-Ubieto A, Jarque I, Iñigo B, Dourdil V, de Arriba F, Pérez-Ávila CC, Gonzalez Y, Hernández MT, Bargay J, Granell M, Rodríguez-Otero P, Silvent M, Cabrera C, Rios R, Alegre A, Gironella M, Gonzalez MS, Sureda A, Sampol A, Ocio EM, Krsnik I, García A, García-Mateo A, Soler JA, Martín J, Arguiñano JM, Mateos MV, Bladé J, San-Miguel JF, Lahuerta JJ, Martínez-López J; GEM/PETHEMA (Grupo Español de Mieloma/Programa para el Estudio de la Terapéutica en Hemopatías Malignas) cooperative study group.

2022

doi: 10.3390/pharmaceutics14040878

Systematic Review of Pharmacogenetics of ABC and SLC Transporter Genes in Acute Myeloid Leukemia

Megías-Vericat JE, Martínez-Cuadrón D, Solana-Altabella A, Poveda JL, Montesinos P.

2022

doi: 10.1016/j.jtct.2022.01.020

Post-Transplantation Cyclophosphamide After HLA Identical Compared to Haploidentical Donor Transplant in Acute Myeloid Leukemia: A Study on Behalf of GETH-TC

Bailén R, Pascual-Cascón MJ, Guerreiro M, López-Corral L, Chinea A, Bermúdez A, Sampol A, Heras I, García-Torres E, Torres M, Roca JR, Herruzo B, Sanz J, Fonseca M, Herrera P, Colorado M, Bento L, López-Godino O, Martín-Calvo C, Fernández-Caldas P, Marcos-Jubilar M, Sánchez-Ortega I, Solano C, Noriega V, Humala K, Oarbeascoa G, Díez-Martín JL, Kwon M; Grupo Español de Trasplante Hematopoyético y Terapia Celular (GETH).

2022

doi: 10.1182/bloodadvances.2021005335

Treatment patterns and outcomes of 2310 patients with secondary acute myeloid leukemia: a PETHEMA registry study

Martínez-Cuadrón D, Megías-Vericat JE, Serrano J, Martínez-Sánchez P, Rodríguez-Arbolí E, Gil C, Aguiar E, Bergua J, López-Lorenzo JL, Bernal T, Espadana A, Colorado M, Rodríguez-Medina C, López-Pavía M, Tormo M, Algarra L, Amigo ML, Sayas MJ, Labrador J, Rodríguez-Gutiérrez JI, Benavente C, Costilla-Barriga L, García-Boyero R, Lavilla-Rubira E, Vives S, Herrera P, García-Belmonte D, Herráez MM, Vasconcelos Esteves G, Gómez-Roncero MI, Cabello A, Bautista G, Balerdi A, Mariz J, Boluda B, Sanz MÁ, Montesinos P.

2022

doi: 10.1016/j.esmoop.2022.100403

Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA Interdisciplinary Expert Consensus

Buske C, Dreyling M, Alvarez-Larrán A, Apperley J, Arcaini L, Besson C, Bullinger L, Corradini P, Giovanni Della Porta M, Dimopoulos M, D'Sa S, Eich HT, Foà R, Ghia P, da Silva MG, Gribben J, Hajek R, Harrison C, Heuser M, Kiesewetter B, Kiladjian JJ, Kröger N, Moreau P, Passweg JR, Peyvandi F, Rea D, Ribera JM, Robak T, San-Miguel JF, Santini V, Sanz G, Sonneveld P, von Lilienfeld-Toal M, Wendtner C, Pentheroudakis G, Passamonti F.

2022

doi: 10.1016/j.bioadv.2022.212749

Novel microgel culture system as semi-solid three-dimensional in vitro model for the study of multiple myeloma proliferation and drug resistance

Sandra Clara-Trujillo, Laia Tolosa, Lourdes Cordón, Amparo Sempere, Gloria Gallego Ferrer, José Luis Gómez Ribelles,

2022

doi: 10.1016/j.transci.2022.103438

ABO group-based strategy for inventory management of methylene blue-treated thawed plasma in a blood bank

Asensi Cantó P, Solís Ruiz J, Lloret Madrid P, Navarro Vicente I, Mora Lucas C, Moscardó Martínez A, Bonanad Boix S, Cañada Martínez AJ, De la Rubia Comos J, Gómez Seguí I, Solves Alcaina P.

2022

doi: 10.1111/bjh.1784

Prognostic heterogeneity of adult B-cell precursor acute lymphoblastic leukaemia patients with t(1;19)(q23;p13)/TCF3-PBX1 treated with measurable residual disease-oriented protocols

Ribera J, Granada I, Morgades M, González T, Ciudad J, Such E, Calasanz MJ, Mercadal S, Coll R, González-Campos J, Tormo M, García-Cadenas I, Gil C, Cervera M, Barba P, Costa D, Ayala R, Bermúdez A, Orfao A, Ribera JM;

2022

doi: 10.1080/10428194.2021.2012667

Phase I trials of the lysine-specific demethylase 1 inhibitor, GSK2879552, as mono- and combination-therapy in relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes

Roboz GJ, Yee K, Verma A, Borthakur G, de la Fuente Burguera A, Sanz G, Mohammad HP, Kruger RG, Karpinich NO, Ferron-Brady G, Acusta A, Del Buono H, Collingwood T, Ballas M, Dhar A, Wei AH.

2022

doi: 10.1080/10428194.2021.1971216

A randomized phase II study comparing consolidation with a single dose of 90 Y ibritumomab tiuxetan vs. maintenance with rituximab for two years in patients with newly diagnosed follicular lymphoma responding to R-CHOP. Long-term follow-up results

López-Guillermo A, Canales MÁ, Dlouhy I, Mercadal S, Briones J, Martín García-Sancho A, Sancho JM, Moraleda JM, Terol MJ, Salar A, Palomera L, Gardella S, Jarque I, Ferrer S, Bargay J, López A, Panizo C, Muntañola A, Montalbán C, Conde E, Hernández MT, Soler A, García Marco JA, Deben G, Marín J, Tomás JF; PETHEMA/GELTAMO/GELCAB Spanish Intergroup.

2022

doi: 10.1056/NEJMoa2109965

Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia

effault de Latour R, Kulasekararaj A, Iacobelli S, Terwel SR, Cook R, Griffin M, Halkes CJM, Recher C, Barraco F, Forcade E, Vallejo JC, Drexler B, Mear JB, Smith AE, Angelucci E, Raymakers RAP, de Groot MR, Daguindau E, Nur E, Barcellini W, Russell NH, Terriou L, Iori AP, La Rocca U, Sureda A, Sánchez-Ortega I, Xicoy B, Jarque I, Cavenagh J, Sicre de Fontbrune F, Marotta S, Munir T, Tjon JML, Tavitian S, Praire A, Clement L, Rabian F, Marano L, Hill A, Palmisani E, Muus P, Cacace F, Frieri C, van Lint MT, Passweg JR, Marsh JCW, Socié G, Mufti GJ, Dufour C, Risitano AM; Severe Aplastic Anemia Working Party of the European Society for Blood and Marrow Transplantation.

2021

doi: 10.1002/cncr.33828.

Results of a randomized phase 3 study of oral sapacitabine in elderly patients with newly diagnosed acute myeloid leukemia (SEAMLESS)

Kantarjian HM, Begna KH, Altman JK, Goldberg SL, Sekeres MA, Strickland SA, Arellano ML, Claxton DF, Baer MR, Gautier M, Berman E, Seiter K, Solomon SR, Schiller GJ, Luger SM, Butrym A, Gaidano G, Thomas XG, Montesinos P, Rizzieri DA, Quick DP, Venugopal P, Gaur R, Maness LJ, Kadia TM, Ravandi F, Buyse ME, Chiao JH.

2021

doi: 10.1182/blood.2021012781

Association of unbalanced translocation der(1;7) with germline GATA2 mutations

Kozyra EJ, Göhring G, Hickstein DD, Calvo KR, DiNardo CD, Dworzak M, de Haas V, Starý J, Hasle H, Shimamura A, Fleming MD, Inaba H, Lewis S, Hsu AP, Holland SM, Arnold DE, Mecucci C, Keel SB, Bertuch AA, Tawana K, Barzilai S, Hirabayashi S, Onozawa M, Lei S, Alaiz H, Andrikovics H, Betts D, Beverloo BH, Buechner J, Čermák M, Cervera J, Haus O, Jahnukainen K, Manola KN, Nebral K, Pasquali F, Tchinda J, Turkiewicz D, Van Roy N, Zemanova Z, Pastor VB, Strahm B, Noellke P, Niemeyer CM, Schlegelberger B, Yoshimi A, Wlodarski MW.

2021

doi: 10.1016/j.transci.2021.103342. Online ahead of print.

Acute hemolytic reaction by anti-Wra: Case report and review of the hemovigilance database of a tertiary care hospital

Solves P, Tur S, Gómez-Seguí I, Viel M, Eiris J, Planells Y, Rodríguez R, Peñalver I, Castro E, de la Rubia J.

2021

doi: 10.1128/mBio.02315-21

Evolutionary and Phenotypic Characterization of Two Spike Mutations in European Lineage 20E of SARS-CoV-2

Ruiz-Rodriguez P, Francés-Gómez C, Chiner-Oms Á, López MG, Jiménez-Serrano S, Cancino-Muñoz I, Ruiz-Hueso P, Torres-Puente M, Bracho MA, D'Auria G, Martinez-Priego L, Guerreiro M, Montero-Alonso M, Gómez MD, Piñana JL; SeqCOVID-SPAIN Consortium, González-Candelas F, Comas I, Marina A, Geller R, Coscolla M.

2021

doi: 10.1080/21645515.2021.1953346

Adjuvanted recombinant zoster vaccine in adult autologous stem cell transplant recipients: polyfunctional immune responses and lessons for clinical practice

Stadtmauer EA, Sullivan KM, El Idrissi M, Salaun B, Alonso Alonso A, Andreadis C, Anttila VJ, Bloor AJ, Broady R, Cellini C, Cuneo A, Dagnew AF, Di Paolo E, Eom H, González-Rodríguez AP, Grigg A, Guenther A, Heineman TC, Jarque I, Kwak JY, Lucchesi A, Oostvogels L, Polo Zarzuela M, Schuind AE, Shea TC, Sinisalo UM, Vural F, Yáñez San Segundo L, Zachée P, Bastidas A.

2021

doi: 10.1002/ajh.26385

SARS-CoV-2-reactive antibody detection after SARS-CoV-2 vaccination in hematopoietic stem cell transplant recipients: Prospective survey from the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group

Piñana JL, López-Corral L, Martino R, Montoro J, Vazquez L, Pérez A, Martin-Martin G, Facal-Malvar A, Ferrer E, Pascual MJ, Sanz-Linares G, Gago B, Sanchez-Salinas A, Villalon L, Conesa-Garcia V, Olave MT, López-Jimenez J, Marcos-Corrales S, García-Blázquez M, Garcia-Gutiérrez V, Hernández-Rivas JÁ, Saus A, Espigado I, Alonso C, Hernani R, Solano C, Ferrer-Lores B, Guerreiro M, Ruiz-García M, Muñoz-Bellido JL, Navarro D, Cedillo A, Sureda A; Infectious Complications Subcommittee of the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group (GETH-TC)

2021

doi: 10.1038/s41375-021-01425-9

Long-term survival after intensive chemotherapy or hypomethylating agents in AML patients aged 70 years and older: a large patient data set study from European registries

Récher C, Röllig C, Bérard E, Bertoli S, Dumas PY, Tavitian S, Kramer M, Serve H, Bornhäuser M, Platzbecker U, Müller-Tidow C, Baldus CD, Martínez-Cuadrón D, Serrano J, Martínez-Sánchez P, Arbolí ER, Gil C, Bergua J, Bernal T, de la Fuente Burguera A, Delabesse E, Bidet A, Pigneux A, Montesinos P.

2021

doi: 10.3390/ma14237121

Biomimetic 3D Environment Based on Microgels as a Model for the Generation of Drug Resistance in Multiple Myeloma

Marín-Payá JC, Díaz-Benito B, Martins LA, Trujillo SC, Cordón L, Lanceros-Méndez S, Gallego Ferrer G, Sempere A, Gómez Ribelles JL.

2021

doi: 10.1182/blood.2021012319

Validation of the International Myeloma Working Group standard response criteria in the PETHEMA/GEM2012MENOS65 study: are these times of change?

iménez-Ubieto A, Paiva B, Puig N, Cedena MT, Martínez-López J, Oriol A, Blanchard MJ, Ríos R, Martin J, Martínez R, Sureda A, Hernández MT, de la Rubia J, Krnisk I, Cabañas V, Palomera L, Sánchez-Pina JM, Bargay J, Mateos MV, Rosiñol L, Blade J, San Miguel J, Lahuerta JJ; GEM (Grupo Español de Mieloma)/PETHEMA (Programa Español de Tratamientos en Hematología) Cooperative Study Group.

2021

doi: 10.1016/j.clml.2021.06.024

Frequency, Clinical Characteristics and Outcome of Adults With Acute Lymphoblastic Leukemia and COVID 19 Infection in the First vs. Second Pandemic Wave in Spain

ibera JM, Morgades M, Coll R, Barba P, López-Lorenzo JL, Montesinos P, Foncillas MA, Cabrero M, Gómez-Centurión I, Morales MD, Varela MR, Herrera P, García-Cadenas I, Calbacho M, Torrent A, Maluquer C, Calabuig M, Garcia-Guiñon A, Bautista G, Llorente L, Gil C, Artola MT, González-Campos J, Fernández-Moreno A, Bárez A, Giménez-Pérez T, Bergua J, Sánchez-Sánchez MJ, Mateos MC, Piñana JL.

2021

doi: 10.1038/s41409-021-01479-4

The impact of GVHD on outcomes after adult single cord blood transplantation in European and Japanese populations

Kanda J, Hayashi H, Ruggeri A, Kimura F, Volt F, Takahashi S, Kako S, Tozatto-Maio K, Yanada M, Sanz G, Uchida N, Angelucci E, Kato S, Mohty M, Forcade E, Tanaka M, Sierra J, Ohta T, Saccardi R, Fukuda T, Ichinohe T, Kimura T, Rocha V, Okamoto S, Nagler A, Atsuta Y, Gluckman E.

2021

doi: 10.1038/s41408-021-00555-8

6-month follow-up of VIALE-C demonstrates improved and durable efficacy in patients with untreated AML ineligible for intensive chemotherapy (141/150)

Wei AH, Panayiotidis P, Montesinos P, Laribi K, Ivanov V, Kim I, Novak J, Stevens DA, Fiedler W, Pagoni M, Bergeron J, Ting SB, Hou JZ, Anagnostopoulos A, McDonald A, Murthy V, Yamauchi T, Wang J, Chyla B, Sun Y, Jiang Q, Mendes W, Hayslip J, DiNardo CD.

2021

doi: 10.1080/10428194.2021.1992619. Online ahead of print.

Spanish Society of Hematology and Hemotherapy expert consensus opinion for SARS-CoV-2 vaccination in onco-hematological patients

Piñana JL, Vázquez L, Martino R, de la Cámara R, Sureda A, Rodríguez-Veiga R, Garrido A, Sierra J, Ribera JM, Torrent A, Mateos MV, de la Rubia J, Tormo M, Díez-Campelo M, García-Gutiérrez V, Álvarez-Larrán A, Sancho JM, MartínGarcía-Sancho A, Yañez L, Pérez Simón JA, Barba P, Abrisqueta P, Álvarez-Twose I, Bonanad S, Lecumberri R, Ruiz-Camps I, Navarro D, Hernández-Rivas JÁ, Cedillo Á, García-Sanz R, Bosch F.

2021

doi: 10.1038/s41598-021-00050-x

Prognostic significance of FLT3-ITD length in AML patients treated with intensive regimens

Castaño-Bonilla T, Alonso-Dominguez JM, Barragán E, Rodríguez-Veiga R, Sargas C, Gil C, Chillón C, Vidriales MB, García R, Martínez-López J, Ayala R, Larrayoz MJ, Anguita E, Cuello R, Cantalapiedra A, Carrillo E, Soria-Saldise E, Labrador J, Recio I, Algarra L, Rodríguez-Medina C, Bilbao-Syeiro C, López-López JA, Serrano J, De Cabo E, Sayas MJ, Olave MT, Sánchez-García J, Mateos M, Blas C, López-Lorenzo JL, Lainez-Gonzalez D, Serrano J, Martínez-Cuadrón D, Sanz MA, Montesinos P.

2021

doi: 10.1038/s41467-021-26551-x

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Lin WY, Fordham SE, Hungate E, Sunter NJ, Elstob C, Xu Y, Park C, Quante A, Strauch K, Gieger C, Skol A, Rahman T, Sucheston-Campbell L, Wang J, Hahn T, Clay-Gilmour AI, Jones GL, Marr HJ, Jackson GH, Menne T, Collin M, Ivey A, Hills RK, Burnett AK, Russell NH, Fitzgibbon J, Larson RA, Le Beau MM, Stock W, Heidenreich O, Alharbi A, Allsup DJ, Houlston RS, Norden J, Dickinson AM, Douglas E, Lendrem C, Daly AK, Palm L, Piechocki K, Jeffries S, Bornhäuser M, Röllig C, Altmann H, Ruhnke L, Kunadt D, Wagenführ L, Cordell HJ, Darlay R, Andersen MK, Fontana MC, Martinelli G, Marconi G, Sanz MA, Cervera J, Gómez-Seguí I, Cluzeau T, Moreilhon C, Raynaud S, Sill H, Voso MT, Lo-Coco F, Dombret H, Cheok M, Preudhomme C, Gale RE, Linch D, Gaal-Wesinger J, Masszi A, Nowak D, Hofmann WK, Gilkes A, Porkka K, Milosevic Feenstra JD, Kralovics R, Grimwade D, Meggendorfer M, Haferlach T, Krizsán S, Bödör C, Stölzel F, Onel K, Allan JM.

2021

doi: 10.1038/s41408-021-00568-3

A prospective biomarker analysis of alvocidib followed by cytarabine and mitoxantrone in MCL-1-dependent relapsed/refractory acute myeloid leukemia

Zeidner JF, Lin TL, Vigil CE, Fine G, Yair Levy M, Nazha A, Esteve J, Lee DJ, Yee K, Dalovisio A, Wang ES, Bergua Burgues JM, Schriber J, Litzow MR, Frankfurt O, Castillo TBD, Bhatt VR, Bhatnagar B, Mehta P, Dillon R, Vicente MV, Anthony S, Bearss D, Montesinos P, Douglas Smith B.

2021

doi: 10.1182/bloodadvances.2020004055

A predictive algorithm using clinical and laboratory parameters may assist in ruling out and in diagnosing MDS

Oster HS, Crouch S, Smith A, Yu G, Abu Shrkihe B, Baruch S, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Cermak J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T, Mittelman M. A

2021

doi: 10.1016/j.jtct.2021.09.008

Post-Transplantation Cyclophosphamide for Graft-versus- Host Disease Prophylaxis in Multiple Myeloma Patients Who Underwent Allogeneic Hematopoietic Cell Transplantation: First Comparison by Donor Type. A Study from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

Sahebi F, Eikema DJ, Koster L, Kroger N, Meijer E, van Doesum JA, Rovira M, Koc Y, Angelucci E, Blaise D, Sammassimo S, McDonald A, Arroyo CH, Sanchez JF, Forcade E, Castagna L, Stölzel F, Sanz J, Tischer J, Ciceri F, Valcarcel D, Proia A, Hayden PJ, Beksac M, Yakoub-Agha I, Schönland S.

2021

doi: 10.1016/j.medcli.2021.03.040.

Recommendations for the diagnosis and treatment of patients with thrombotic thrombocytopenic purpura

Mingot Castellano ME, Pascual Izquierdo C, González A, Viejo Llorente A, Valcarcel Ferreiras D, Sebastián E, García Candel F, Sarmiento Palao H, Gómez Seguí I, de la Rubia J, Cid J, Martínez Nieto J, Hernández Mateo L, Goterris Viciedo R, Fidalgo T, Salinas R, Del Rio-Garma J; Grupo Español de Aféresis (GEA).

2021

doi: 10.1038/s41409-021-01417-4

Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation

de Koning C, Tao W, Lacna A, van Veghel K, Horwitz ME, Sanz G, Jagasia MH, Wagner JE, Stiff PJ, Hanna R, Cilloni D, Valcárcel D, Peled T, Galamidi Cohen E, Goshen U, Pandit A, Lindemans CA, Jan Boelens J, Nierkens S.

2021

doi: 10.1080/10428194.2021.1948031

Characteristics, clinical outcomes, and risk factors of SARS-COV-2 infection in adult acute myeloid leukemia patients: experience of the PETHEMA group

alanques-Pastor T, Megías-Vericat JE, Martínez P, López Lorenzo JL, Cornago Navascués J, Rodriguez Macias G, Cano I, Arnan Sangerman M, Vidriales Vicente MB, Algarra Algarra JL, Foncillas MÁ, Herrera P, Botella Prieto C, Vives S, Figuera Álvarez Á, Cuevas Palomares L, Sobas M, Contento Gonzalo A, Cuello García R, Amutio Diez ME, De Miguel Llorente D, Navas Elorza B, Bergua Burgues JM, Bernal Del Castillo T, Mateos Rodríguez MC, de Cabo López E, Franco Villegas AC, García Boyero R, Escolano Escobar C, Seri Merino C, Cervero C, Roldán Pérez A, Hermosín Ramos L, Cervera Calvo M, Olave MT, Villafuerte Gutiérrez P, de Laiglesiai A, Serrano J, Najera Irazu MJ, Piñana JL, Sanz MÁ, Martínez-López J, Montesinos P.

2021

doi: 10.1038/s41375-021-01323-0

Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results

Rücker FG, Du L, Luck TJ, Benner A, Krzykalla J, Gathmann I, Voso MT, Amadori S, Prior TW, Brandwein JM, Appelbaum FR, Medeiros BC, Tallman MS, Savoie L, Sierra J, Pallaud C, Sanz MA, Jansen JH, Niederwieser D, Fischer T, Ehninger G, Heuser M, Ganser A, Bullinger L, Larson RA, Bloomfield CD, Stone RM, Döhner H, Thiede C, Döhner K.

2021

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A 2:1 randomized, open-label, phase II study of selinexor vs. physician’s choice in older patients with relapsed or refractory acute myeloid leukemia

Sweet K, Bhatnagar B, Döhner H, Donnellan W, Frankfurt O, Heuser M, Kota V, Liu H, Raffoux E, Roboz GJ, Röllig C, Showel MM, Strickland SA Jr, Vives S, Tang S, Unger TJ, Joshi A, Shen Y, Alvarez MJ, Califano A, Crochiere M, Landesman Y, Kauffman M, Shah J, Shacham S, Savona MR, Montesinos P. A

2021

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Leukemia not Eligible for Standard Induction Therapy: A Randomized, Phase 3 Trial

Döhner H, Symeonidis A, Deeren D, Demeter J, Sanz MA, Anagnostopoulos A, Esteve J, Fiedler W, Porkka K, Kim HJ, Lee JH, Usuki K, D'Ardia S, Won Jung C, Salamero O, Horst HA, Recher C, Rousselot P, Sandhu I, Theunissen K, Thol F, Döhner K, Teleanu V, DeAngelo DJ, Naoe T, Sekeres MA, Belsack V, Ge M, Taube T, Ottmann OG.

2021

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Management of adverse events in patients with acute myeloid leukemia in remission receiving oral azacitidine: experience from the phase 3 randomized QUAZAR AML-001 trial

Ravandi F, Roboz GJ, Wei AH, Döhner H, Pocock C, Selleslag D, Montesinos P, Sayar H, Musso M, Figuera-Alvarez A, Safah H, Tse W, Sohn SK, Hiwase D, Chevassut T, Pierdomenico F, La Torre I, Skikne B, Bailey R, Zhong J, Beach CL, Dombret H.

2021

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Addition of chemotherapy to nivolumab after PD-1 inhibitor failure as bridge to allogeneic stem cell transplantation in classical Hodgkin’s lymphoma: report on three cases and literature review

Romero S, Balaguer-Roselló A, Montoro J, Beneit P, Martínez A, Ruiz C, Andreu R, Guerreiro M, Arnao M, Montava A, Vicente AI, Jarque I, Sanz J.

2021

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Real-World Characteristics and Outcome of Patients Treated With Single-Agent Ibrutinib for Chronic Lymphocytic Leukemia in Spain (IBRORS-LLC Study

Abrisqueta P, Loscertales J, Terol MJ, Ramírez Payer Á, Ortiz M, Pérez I, Cuellar-García C, Fernández de la Mata M, Rodríguez A, Lario A, Delgado J, Godoy A, Arguiñano Pérez JM, Berruezo MJ, Oliveira A, Hernández-Rivas JÁ, García Malo MD, Medina Á, García Martin P, Osorio S, Baltasar P, Fernández-Zarzoso M, Marco F, Vidal Manceñido MJ, Smucler Simonovich A, López Rubio M, Jarque I, Suarez A, Fernández Álvarez R, Lancharro Anchel A, Ríos E, Losada Castillo MDC, Pérez Persona E, García Muñoz R, Ramos R, Yáñez L, Bello JL, Loriente C, Acha D, Villanueva M.

2021

doi: 10.3390/ijms22136963

Aberrant Alternative Splicing in U2af1/Tet2 Double Mutant Mice Contributes to Major Hematological Phenotypes

Martínez-Valiente C, Garcia-Ruiz C, Rosón B, Liquori A, González-Romero E, Fernández-González R, Gómez-Redondo I, Cervera J, Gutiérrez-Adán A, Sanjuan-Pla A.

2021

doi: 10.1002/cam4.3904

Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia

Emiliano Fabiani, Laura Cicconi, Anna Maria Nardozza, Antonio Cristiano, Marianna Rossi, Tiziana Ottone, Giulia Falconi, Mariadomenica Divona, Anna Maria Testi, Ombretta Annibali, Roberto Castelli, Vladimir Lazarevic, Eduardo Rego, Pau Montesinos, Jordi Esteve, Adriano Venditti, Matteo Della Porta, William Arcese, Francesco Lo-Coco, Maria Teresa Voso

2021

doi: 10.1093/infdis/jiaa553

Seasonal Human Coronavirus Respiratory Tract Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation

Piñana JL, Xhaard A, Tridello G, Passweg J, Kozijn A, Polverelli N, Heras I, Perez A, Sanz J, Berghuis D, Vázquez L, Suárez-Lledó M, Itäla-Remes M, Ozcelik T, Iturrate Basarán I, Karakukcu M, Al Zahrani M, Choi G, Cuesta Casas MA, Batlle Massana M, Viviana A, Blijlevens N, Ganser A, Kuskonmaz B, Labussière-Wallet H, Shaw PJ, Yegin ZA, González-Vicent M, Rocha V, Ferster A, Knelange N, Navarro D, Mikulska M, de la Camara R, Styczynski J.

2021

doi: 10.1016/j.leukres.2021.106612

Adverse prognostic impact of complex karyotype (≥3 cytogenetic alterations) in adult T-cell acute lymphoblastic leukemia (T-ALL)

Genescà E, Morgades M, González-Gil C, Fuster-Tormo F, Haferlach C, Meggendorfer M, Montesinos P, Barba P, Gil C, Coll R, Moreno MJ, Martínez-Carballeira D, García-Cadenas I, Vives S, Ribera J, González-Campos J, Díaz-Beya M, Mercadal S, Artola MT, Cladera A, Tormo M, Bermúdez A, Vall-Llovera F, Martínez-Sánchez P, Amigo ML, Monsalvo S, Novo A, Cervera M, García-Guiñon A, Ciudad J, Cervera J, Hernández-Rivas JM, Granada I, Haferlach T, Orfao A, Solé F, Ribera JM.

2021

doi: 10.1080/10428194.2021.1938031

Evolving patterns of care and outcomes in relapsed/refractory FLT3 mutated acute myeloid leukemia adult patients

Boluda B, Martínez-Cuadrón D, Algarra L, Cano I, Sayas MJ, Acuña-Cruz E, Blanco A, Marco-Ayala J, DeLapuerta R, Díaz-González Á, Tormo M, Rodríguez-Veiga R, García R, Piñana JL, López-Pavía M, Barragán E, Amigo ML, Sargas C, López A, Solana-Altabella A, Gil C, Megías-Vericat JE, Sanz MA, Montesinos P.

2021

doi: 10.1177/26348535211028192

NPM1+ /FLT3- Acute Myeloid Leukemia after JAK2-V617F+ Essential Thrombocythemia. Management and Prognosis

Baldomero Moriano, Eva Barragan, Oscar Ferré, Ignacio Casas, Julio Prieto-Fernandez, Carmen Hernandez, Sara Cáceres, Sara Suárez, Rocío Cardesa, María José Arcos, Helena Bañas, Juan Miguel Bergua

2021

doi: 10.1038/s41591-021-01367-w

Author Correction: Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Bernard E, Nannya Y, Hasserjian RP, Devlin SM, Tuechler H, Medina-Martinez JS, Yoshizato T, Shiozawa Y, Saiki R, Malcovati L, Levine MF, Arango JE, Zhou Y, Solé F, Cargo CA, Haase D, Creignou M, Germing U, Zhang Y, Gundem G, Sarian A, van de Loosdrecht AA, Jädersten M, Tobiasson M, Kosmider O, Follo MY, Thol F, Pinheiro RF, Santini V, Kotsianidis I, Boultwood J, Santos FPS, Schanz J, Kasahara S, Ishikawa T, Tsurumi H, Takaori-Kondo A, Kiguchi T, Polprasert C, Bennett JM, Klimek VM, Savona MR, Belickova M, Ganster C, Palomo L, Sanz G, Ades L, Della Porta MG, Smith AG, Werner Y, Patel M, Viale A, Vanness K, Neuberg DS, Stevenson KE, Menghrajani K, Bolton KL, Fenaux P, Pellagatti A, Platzbecker U, Heuser M, Valent P, Chiba S, Miyazaki Y, Finelli C, Voso MT, Shih LY, Fontenay M, Jansen JH, Cervera J, Atsuta Y, Gattermann N, Ebert BL, Bejar R, Greenberg PL, Cazzola M, Hellström-Lindberg E, Ogawa S, Papaemmanuil E

2021

doi: 10.1038/s41409-021-01319-5

Common seasonal respiratory virus infections in allogeneic stem cell transplant recipients during the SARS-COV-2 pandemic

Rosalía De la Puerta, Juan Montoro, Carla Aznar, Ignacio Lorenzo, Eva María González-Barberá, Aitana Balaguer-Roselló, Manuel Guerreiro, Lara Domínguez, Miguel Salavert, Cristóbal Aguilar, Javier de la Rubia, Jaime Sanz, María Dolores Gómez, José Luis Piñana

2021

doi: 10.1002/jca.21901

Extracorporeal photopheresis vs standard therapies for steroid-refractory chronic graft-vs-host disease: Pharmacoeconomic assessment of hospital resource use in Spain

Blanca Boluda, Antonio Solana-Altabella, Isafer Cano, Evelyn Acuña-Cruz, Rebeca Rodríguez-Veiga, Octavio Ballesta-López , Juan Eduardo Megías-Vericat, David Martínez-Cuadrón, Ines Gómez, Pila Solves, Indignacio Lorenzo, Jose Luis Piñana, Jaime Sanz, Manuel Guerreiro, Juan Montoro Gómez, Alvaro Díaz-González, Javier Marco, Ana Blanco, Miguel Á Sanz, Pau Montesinos

2021

doi: 10.1002/cam4.3881

Real-world evidence of tisagenlecleucel for the treatment of relapsed or refractory large B-cell lymphoma

Gloria Iacoboni, Guillermo Villacampa, Nuria Martinez-Cibrian, Rebeca Bailén, Lucia Lopez Corral, Jose M Sanchez, Manuel Guerreiro, Ana Carolina Caballero, Alberto Mussetti, Juan-Manuel Sancho, Rafael Hernani, Pau Abrisqueta, Carlos Solano, Anna Sureda, Javier Briones, Alejandro Martin Garcia-Sancho, Mi Kwon, Juan Luis Reguera-Ortega, Pere Barba , GETH, GELTAMO Spanish Groups

2021

doi: 10.1186/s13045-021-01086-2

Allogeneic hematopoietic cell transplantation with cord blood versus mismatched unrelated donor with post-transplant cyclophosphamide in acute myeloid leukemia

Bhagirathbhai Dholaria, Myriam Labopin, Jaime Sanz, Annalisa Ruggeri, Jan Cornelissen, Hélène Labussière-Wallet, Didier Blaise, Edouard Forcade, Patrice Chevallier, Anna Grassi, Ludmila Zubarovskaya, Jürgen Kuball, Patrice Ceballos, Fabio Ciceri, Frederic Baron, Bipin N Savani, Arnon Nagler, Mohamad Mohty

2021

doi: 10.3390/cancers13102458

The Mutational Landscape of Acute Myeloid Leukaemia Predicts Responses and Outcomes in Elderly Patients from the PETHEMA-FLUGAZA Phase 3 Clinical Trial

Rosa Ayala, Inmaculada Rapado, Esther Onecha, David Martínez-Cuadrón, Gonzalo Carreño-Tarragona, Juan Miguel Bergua, Susana Vives, Jesus Lorenzo Algarra, Mar Tormo, Pilar Martinez, Josefina Serrano, Pilar Herrera, Fernando Ramos, Olga Salamero, Esperanza Lavilla, Cristina Gil, Jose Luis López Lorenzo, María Belén Vidriales, Jorge Labrador, José Francisco Falantes, María José Sayas, Bruno Paiva, Eva Barragán, Felipe Prosper, Miguel Ángel Sanz, Joaquín Martínez-López, Pau Montesinos, On Behalf Of The Programa Para El Estudio de la Terapeutica En Hemopatias Malignas Pethema Cooperative Study Group

2021

doi: 10.1182/bloodadvances.2020001834

Caplacizumab prevents refractoriness and mortality in acquired thrombotic thrombocytopenic purpura: integrated analysis

Flora Peyvandi, Spero Cataland, Marie Scully, Paul Coppo, Paul Knoebl, Johanna A Kremer Hovinga, Ara Metjian, Javier de la Rubia, Katerina Pavenski, Jessica Minkue Mi Edou, Hilde De Winter, Filip Callewaert

2021

doi: 10.1038/s41409-021-01317-7

Comparing outcomes of a second allogeneic hematopoietic cell transplant using HLA-matched unrelated versus T-cell replete haploidentical donors in relapsed acute lymphoblastic leukemia: a study of the Acute Leukemia Working Party of EBMT

Kharfan-Dabaja MA, Labopin M, Bazarbachi A, Ciceri F, Finke J, Bruno B, Bornhäuser M, Gedde-Dahl T, Labussière-Wallet H, Niittyvuopio R, Valerius T, Angelucci E, Brecht A, Caballero D, Kuball J, Potter V, Schmid C, Tischer J, Zuckerman T, Benedetti F, Blaise D, Diez-Martin JL, Sanz J, Ruggeri A, Brissot E, Savani BN, Giebel S, Nagler A, Mohty M.

2021

doi: 10.1200/JCO.20.01659.

Classification and Personalized Prognostic Assessment on the Basis of Clinical and Genomic Features in Myelodysplastic Syndromes

Bersanelli M, Travaglino E, Meggendorfer M, Matteuzzi T, Sala C, Mosca E, Chiereghin C, Di Nanni N, Gnocchi M, Zampini M, Rossi M, Maggioni G, Termanini A, Angelucci E, Bernardi M, Borin L, Bruno B, Bonifazi F, Santini V, Bacigalupo A, Voso MT, Oliva E, Riva M, Ubezio M, Morabito L, Campagna A, Saitta C, Savevski V, Giampieri E, Remondini D, Passamonti F, Ciceri F, Bolli N, Rambaldi A, Kern W, Kordasti S, Sole F, Palomo L, Sanz G, Santoro A, Platzbecker U, Fenaux P, Milanesi L, Haferlach T, Castellani G, Della Porta MG.

2021

doi: 10.1111/bjh.17426

Second allogeneic haematopoietic cell transplantation using HLA-matched unrelated versus T-cell replete haploidentical donor and survival in relapsed acute myeloid leukaemia

Kharfan-Dabaja MA, Labopin M, Brissot E, Kroger N, Finke J, Ciceri F, Deconinck E, Blaise D, Chevallier P, Gramatzki M, Ganser A, Stelljes M, Edinger M, Savani B, Ruggeri A, Sanz J, Nagler A, Mohty M.

2021

doi: 10.1111/vox.13061

International Forum on Transfusion Practices in Haematopoietic Stem-Cell Transplantation: Summary

Pilar Solves, Miquel Lozano, Eugene Zhiburt, Javier Anguita Velasco, Ana Maria Pérez-Corral, Silvia Monsalvo-Saornil, Sho Yamazaki, Hitoshi Okazaki, Kathleen Selleng, Konstanze Aurich, William Krüger, Andreas Buser, Andreas Holbro, Laura Infanti, Gregor Stehle, Luca Pierelli, Antonella Matteocci, Luigi Rigacci, Karen M K De Vooght, Jurgen H E Kuball, Katherine L Fielding, David A Westerman, Erica M Wood, Claudia S Cohn, Andrew Johnson, Mickey B C Koh, Dara Qadir, Christine Cserti-Gazdewich, Etienne Daguindau, Fanny Angelot-Delettre, Pierre Tiberghien, Silvano Wendel-Neto, Roberta-Maria Fachini, Suzy Morton, Charles Craddock, Matthew Lumley, Jolanta Antoniewicz-Papis, Kazimierz Hałaburda, Magdalena Łętowska, Nancy Dunbar

2021

doi: 10.1007/s00277-021-04529-5

Treatment patterns and outcomes in real-world transplant-ineligible patients newly diagnosed with multiple myeloma

María José Cejalvo, Gabriela Bustamante, Esther González, Judith Vázquez-Álvarez, Ricarda García, Ángel Ramírez-Payer, Ernesto Pérez-Persona, Eugenia Abella, Sebastián Garzón, Antoni García, Isidro Jarque, Marta Sonia González, Antonia Sampol, Cristina Motlló, Josep María Martí, Magdalena Alcalá, Rafael Duro, Yolanda González, José Luis Sastre, Josep Sarrà, Giselle Lostaunau, Rocío López, Javier de la Rubia

2021

doi: 10.1007/s00277-021-04542-8

A phase I trial of selinexor plus FLAG-Ida for the treatment of refractory/relapsed adult acute myeloid leukemia patients

María P Martínez Sánchez, Juan Eduardo Megías-Vericat, Rebeca Rodríguez-Veiga, Susana Vives, Juan Miguel Bergua, Anna Torrent, Sara Suárez-Varela, Blanca Boluda, Joaquín Martínez-López, Isabel Cano-Ferri, Evelyn Acuña-Cruz, Laura Torres-Miñana, Beatriz Martín-Herreros, Alfons Serrano, Amparo Sempere, Eva Barragán, Claudia Sargas, Miguel Sanz, David Martínez-Cuadrón, Pau Montesinos, PETHEMA group

2021

doi: 10.2147/CEOR.S302097

Cost-Effectiveness Analysis of Gemtuzumab Ozogamicin for First-Line Treatment of Patients with Cd-33 Positive Acute Myeloid Leukaemia in Spain

Maria Mareque, Pau Montesinos, Patricia Font, José María Guinea, Adolfo de la Fuente, Javier Soto, Itziar Oyagüez, James Brockbank, Tamara Iglesias, Julia Llinares, Jorge Sierra

2021

doi: 10.1002/pbc.28819

The reliability of bone marrow cytology as response criterion in metastatic neuroblastoma

Schumacher-Kuckelkorn R, Atra A, Belli ML, den Engelsman G, Fréneaux P, Gauthier A, Heijlaerts-Klever A, Scuderi F, Senent Peris L, Tewari S, Zapletal O, Ernst A, Berthold F.

2021

doi: 10.1016/S2352-3026(20)30394-X

Development and validation of a disease risk stratification system for patients with haematological malignancies: a retrospective cohort study of the European Society for Blood and Marrow Transplantation registry

Shouval R, Fein JA, Labopin M, Cho C, Bazarbachi A, Baron F, Bug G, Ciceri F, Corbacioglu S, Galimard JE, Giebel S, Gilleece MH, Giralt S, Jakubowski A, Montoto S, O'Reilly RJ, Papadopoulos EB, Peric Z, Ruggeri A, Sanz J, Sauter CS, Savani BN, Schmid C, Spyridonidis A, Tamari R, Versluis J, Yakoub-Agha I, Perales MA, Mohty M, Nagler A.

2021

doi: 10.1097/FPC.0000000000000431

Influence of polymorphisms in anthracyclines metabolism genes in the standard induction chemotherapy of acute myeloid leukemia

Megías-Vericat JE, Martínez-Cuadrón D, Herrero MJ, Rodríguez-Veiga R, Solana-Altabella A, Boluda B, Ballesta-López O, Cano I, Acuña-Cruz E, Cervera J, Poveda JL, Sanz MÁ, Aliño SF, Montesinos P.

2021

doi: 10.1038/s41375-021-01179-4

Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial

Larson RA, Mandrekar SJ, Huebner LJ, Sanford BL, Laumann K, Geyer S, Bloomfield CD, Thiede C, Prior TW, Döhner K, Marcucci G, Voso MT, Klisovic RB, Galinsky I, Wei AH, Sierra J, Sanz MA, Brandwein JM, de Witte T, Niederwieser D, Appelbaum FR, Medeiros BC, Tallman MS, Krauter J, Schlenk RF, Ganser A, Serve H, Ehninger G, Amadori S, Gathmann I, Döhner H, Stone RM.

2021

doi: 10.1002/ajh.26142

Differentiation syndrome with lower-intensity treatments for acute myeloid leukemia

Differentiation syndrome with lower-intensity treatments for acute myeloid leukemia

2021

doi: 10.1111/tid.13602

Adoptive transfer of ex vivo expanded SARS-CoV-2-specific cytotoxic lymphocytes: A viable strategy for COVID-19 immunosuppressed patients?

Guerreiro M, Aguilar-Gallardo C, Montoro J, Francés-Gómez C, Latorre V, Luna I, Planelles D, Carrasco MP, Gómez MD, González-Barberá EM, Aguado C, Sempere A, Solves P, Gómez-Seguí I, Balaguer-Rosello A, Louro A, Perla A, Larrea L, Sanz J, Arbona C, de la Rubia J, Geller R, Sanz MÁ, Sanz G, Luis Piñana J.

2021

doi: 10.1111/ejh.13618

Defibrotide in hematopoietic stem cell transplantation: A multicenter survey study of the Spanish Hematopoietic Stem Cell Transplantation Group (GETH)

González Vicent M, Díaz de Heredia C, González de Pablo J, Molina B, Regueiro A, Pérez Martinez A, Palomo P, López Corral L, García E, Fernández JM, Pérez A, Jiménez MJ, Guerreiro M, Vallejo C, Gallardo AI, López O, Benito A, Marsal J, Duarte M, Bento L, Badell I, Pedraza A, Jiménez Ubieto A, González P, Gómez Centurión I, Costilla L, Beléndez C, Esquirol A, Espigado I, Lavilla E, Díaz MÁ.

2021

doi: 10.1007/s00277-021-04465-4

Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial

Heuser M, Smith BD, Fiedler W, Sekeres MA, Montesinos P, Leber B, Merchant A, Papayannidis C, Pérez-Simón JA, Hoang CJ, O'Brien T, Ma WW, Zeremski M, O'Connell A, Chan G, Cortes JE.

2021

doi: 10.3390/cancers13081947

A single-run next-generation sequencing (Ngs) assay for the simultaneous detection of both gene mutations and large chromosomal abnormalities in patients with myelodysplastic syndromes (mds) and related myeloid neoplasms

iquori, A.; Lesende, I.; Palomo, L.; Avetisyan, G.; Ibáñez, M.; González-Romero, E.; Boluda-Navarro, M.; Morote-Faubel, M.; Garcia-Ruiz, C.; Martinez-Valiente, C.; Santiago-Balsera, M.; Gomez-Seguí, I.; Sanjuan-Pla, A.; Sanz, M.A.; Sanz, G.; Solé, F.; Such, E.; Cervera, J. A

2021

doi: 10.3389/fimmu.2021.625591.

Case Report: Partial Uniparental Disomy Unmasks a Novel Recessive Mutation in the LYST Gene in a Patient With a Severe Phenotype of Chédiak-Higashi Syndrome

Boluda-Navarro M, Ibáñez M, Liquori A, Franco-Jarava C, Martínez-Gallo M, Rodríguez-Vega H, Teresa J, Carreras C, Such E, Zúñiga Á, Colobran R, Cervera JV.

2021

doi: 10.1038/s41375-021-01126-3

Impact of measurable residual disease by decentralized flow cytometry: a PETHEMA real-world study in 1076 patients with acute myeloid leukemia

Paiva B, Vidriales MB, Sempere A, Tarín F, Colado E, Benavente C, Cedena MT, Sánchez J, Caballero-Velazquez T, Cordón L, Garces JJ, Simoes C, Martínez-Cuadrón D, Bernal T, Botella C, Grille S, Serrano J, Rodríguez-Medina C, Algarra L, Alonso-Domínguez JM, Amigo ML, Barrios M, García-Boyero R, Colorado M, Pérez-Oteyza J, Pérez-Encinas M, Costilla-Barriga L, Sayas MJ, Pérez O, González-Díaz M, Pérez-Simón JA, Martínez-López J, Sossa C, Orfao A, San Miguel JF, Sanz MÁ, Montesinos P; PETHEMA (Programa para el Estudio de la Terapéutica en Hemopatías Malignas) cooperative study group.

2021

doi: 10.1158/1078-0432.CCR-20-2809

Comparison of Haploidentical Bone Marrow versus Matched Unrelated Donor Peripheral Blood Stem Cell Transplantation with Posttransplant Cyclophosphamide in Patients with Acute Leukemia

Nagler A, Labopin M, Dholaria B, Angelucci E, Afanasyev B, Cornelissen JJ, Sica S, Meijer E, Ciceri F, Van Gorkom G, Kröger N, Martin H, Pioltelli P, Risitano A, Canaani J, Savani BN, Sanz J, Mohty M.

2021

doi: 10.1002/cncr.33403

A phase 3 trial of azacitidine versus a semi-intensive fludarabine and cytarabine schedule in older patients with untreated acute myeloid leukemia

Vives S, Martínez-Cuadrón D, Bergua Burgues J, Algarra L, Tormo M, Martínez-Sánchez MP, Serrano J, Herrera P, Ramos F, Salamero O, Lavilla E, López-Lorenzo JL, Gil C, Vidriales B, Falantes JF, Serrano A, Labrador J, Sayas MJ, Foncillas MÁ, Amador Barciela ML, Olave MT, Colorado M, Gascón A, Fernández MÁ, Simiele A, Pérez-Encinas MM, Rodríguez-Veiga R, García O, Martínez-López J, Barragán E, Paiva B, Sanz MÁ, Montesinos P; PETHEMA Group.

2021

doi: 10.1111/ejh.13604

Healthcare resource utilization in adult patients with relapsed/refractory FLT3 mutated acute myeloid leukemia: A retrospective chart review from Spain

Solana-Altabella A, Boluda B, Rodríguez-Veiga R, Cano I, Acuña-Cruz E, Blanco A, Marco-Ayala J, de la Puerta R, Díaz-González Á, Piñana JL, Sanz J, Sempere A, Cervera J, Barragán E, Sargas C, Ballesta-López O, Megías-Vericat JE, Martínez-Cuadrón D, Sanz MÁ, Montesinos P.

2021

doi: 10.1016/S2352-3026(20)30374-4

Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study

Lisa Pleyer, Michael Leisch, Alexandra Kourakli, Eric Padron, Jaroslaw Pawel Maciejewski, Blanca Xicoy Cirici, Jennifer Kaivers, Johanna Ungerstedt, Sonja Heibl, Peristera Patiou, Anthony Michael Hunter, Elvira Mora, Klaus Geissler, Maria Dimou, Maria-José Jimenez Lorenzo, Thomas Melchardt, Alexander Egle, Athina-Nora Viniou, Bhumika Jayantibhai Patel, Montserrat Arnan, Peter Valent, Christoforos Roubakis, Teresa Bernal del Castillo, Athanasios Galanopoulos, Marisa Calabuig Muñoz, Nicolas Bonadies, Antonio Medina de Almeida, Jaroslav Cermak, Andrés Jerez, Maria Julia Montoro, Albert Cortés, Alejandro Avendaño Pita, Bernardo Lopez Andrade, Eva Hellstroem-Lindberg, Ulrich Germing, Mikkael Aaron Sekeres, Alan Francis List, Argiris Symeonidis, Guillermo Francisco Sanz, Julian Larcher-Senn, Richard Greil,

2021

doi: 10.1016/S2352-3026(20)30400-2

Proposed global prognostic score for systemic mastocytosis: a retrospective prognostic modelling study

Javier I Muñoz-González, Iván Álvarez-Twose, María Jara-Acevedo, Roberta Zanotti, Cecelia Perkins, Mohamad Jawhar, Wolfgang R Sperr, Khalid Shoumariyeh, Juliana Schwaab, Georg Greiner, Ana Henriques, Carolina Caldas, Carlos Fernández-Giménez, Laura Sánchez-Muñoz, Andrea Mayado, Alba Pérez-Pons, Annette Schmitt-Graeff, Justus Duyster, Ilaria Tanasi, Francesco Olivieri, Elvira Mora-Casterá, Irene Luna, Leonor Senent, Maria-Helena Bañas, Amanda Nuñez-García, Manuel Jurado-Chacón, Guillermo Martín-Sánchez, Enrique Colado, Blanca Xicoy, Georgina Gener-Ricós, Jason Gotlib, Patrizia Bonadonna, Andreas Reiter, Peter Valent, Andrés C García-Montero*, Alberto Orfao*

2021

doi: 10.2217/fon-2020-0700

Gilteritinib use in the treatment of relapsed or refractory acute myeloid leukemia with a FLT3 mutation

Ballesta-López O, Solana-Altabella A, Megías-Vericat JE, Martínez-Cuadrón D, Montesinos P

2021

doi: 10.1016/j.jtct.2020.12.029

Long-Term Outcomes After Autologous Versus Allogeneic Stem Cell Transplantation in Molecularly-Stratified Patients With Intermediate Cytogenetic Risk Acute Myeloid Leukemia: A PETHEMA Study

Eduardo Rodríguez-Arbolí, David Martínez-Cuadrón, Rebeca Rodríguez-Veiga, Estrella Carrillo-Cruz, Cristina Gil-Cortés, Josefina Serrano-López, Teresa Bernal del Castillo, María del Pilar Martínez-Sánchez, Carlos Rodríguez-Medina, Belén Vidriales, Juan Miguel Bergua, Celina Benavente, Raimundo García-Boyero, Pilar Herrera-Puente, Lorenzo Algarra, María José Sayas-Lloris, Rosa Fernández, Jorge Labrador, Esperanza Lavilla-Rubira, Manuel Barrios-García, Mar Tormo, Alfons Serrano-Maestro, Claudia Lucía Sossa-Melo, Daniel García-Belmonte, Susana Vives, Juan Ignacio Rodríguez-Gutiérrez, Carmen Albo-López, María Paz Garrastazul-Sánchez, Mercedes Colorado-Araujo, José Mariz, Miguel Ángel Sanz, José Antonio Pérez-Simón, Pau Montesinos

2020

doi: 10.1182/bloodadvances.2020002904

Midostaurin in patients with acute myeloid leukemia and FLT3-TKD mutations: a subanalysis from the RATIFY trial

Voso MT, Larson RA, Jones D, Marcucci G, Prior T, Krauter J, Heuser M, Lavorgna S, Nomdedeu J, Geyer SM, Walker A, Wei AH, Sierra J, Sanz MA, Brandwein JM, de Witte TM, Jansen JH, Niederwieser D, Appelbaum FR, Medeiros BC, Tallman MS, Schlenk RF, Ganser A, Amadori S, Cheng Y, Chen Y, Pallaud C, Du L, Piciocchi A, Ehninger G, Byrd J, Thiede C, Döhner K, Stone RM, Döhner H, Bloomfield CD, Lo-Coco F.

2020

doi: 10.1016/j.leukres.2020.10647

Outcome of lower-risk myelodysplastic syndrome with ring sideroblasts (MDS-RS) after failure of erythropoiesis- stimulating agents

Park S, Hamel JF, Toma A, Kelaidi C, Thépot S, Campelo MD, Santini V, Sekeres MA, Komrokji R, Steensma D, Balleari E, Götze KS, Kotsianidis I, Guerci-Bresler A, Stamatoullas A, Sanz GF, Germing U, Fenaux P

2020

doi: 10.1111/tid.13507

Kinetics of Torque Teno virus DNA in stools may predict occurrence of acute intestinal graft versus host disease early after allogeneic hematopoietic stem cell transplantation

Bueno F, Albert E, Piñana JL, Pérez A, Úbeda C, Gómez MD, Hernández-Boluda JC, Gonzalez-Barberá EM, Montoro J, Giménez E, Guerreiro M, Balaguer-Roselló A, Hernani R, Sanz J, Solano C, Navarro D.

2020

doi: 10.1038/s41409-020-01162-0.

Hematopoietic stem cell transplantation for adults with relapsed acute promyelocytic leukemia in second complete remission

Sanz J, Labopin M, Sanz MA, Aljurf M, Sousa AB, Craddock C, Zuckerman T, Labussière-Wallet H, Campos A, Grillo G, Ozkurt ZN, Cornelissen JJ, Reményi P, Martino M, Porras RP, Nagler A, Gorin NC, Mohty M; Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT).

2020

doi: 10.1200/JCO.19.03250

First-in-Human Phase I Study of Iadademstat (ORY-1001): A First-in-Class Lysine-Specific Histone Demethylase 1A Inhibitor, in Relapsed or Refractory Acute Myeloid Leukemia

Salamero O, Montesinos P, Willekens C, Pérez-Simón JA, Pigneux A, Récher C, Popat R, Carpio C, Molinero C, Mascaró C, Vila J, Arévalo MI, Maes T, Buesa C, Bosch F, Somervaille TCP.

2020

doi: 10.1056/NEJMoa2004444

Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission

Wei AH, Döhner H, Pocock C, Montesinos P, Afanasyev B, Dombret H, Ravandi F, Sayar H, Jang JH, Porkka K, Selleslag D, Sandhu I, Turgut M, Giai V, Ofran Y, Kizil Çakar M, Botelho de Sousa A, Rybka J, Frairia C, Borin L, Beltrami G, Čermák J, Ossenkoppele GJ, La Torre I, Skikne B, Kumar K, Dong Q, Beach CL, Roboz GJ; QUAZAR AML-001 Trial Investigators

2020

doi: 10.1111/tan.14179

Allogeneic hematopoietic stem cell transplant recipients in Spain: Human leukocyte antigen characteristics and diversity by high-resolution analysis

Guerreiro M, Planelles D, Aguilar-Gallardo C, Lorenzo JI, Montoro J, Sanz J, Balaguer A, Gómez I, Solves P, Pérez A, Blanquer M, Espigado I, Solano C, Piñana JL; Grupo Español de Trasplante Hematopoyético y Terapia Celular (GETH).

2020

doi: 10.1016/j.jtct.2020.12.019

Central Nervous System Involvement in Epstein–Barr Virus-Related Post-Transplant Lymphoproliferative Disorders after Allogeneic Hematopoietic Stem Cell Transplantation

Aitana Balaguer-Rosello, José Luis Piñana, Luis Bataller, Juan Montoro, Samuel Romero, Irene Navarro, Ignacio Lorenzo, Rafael Andreu, Manuel Guerreiro, Cristobal Aguilar, David Gorriz, Lara Dominguez, Rosalia de la Puerta, Inés Gómez, Pilar Solves, Isidro Jarque, Miguel Ángel Sanz, Guillermo Sanz, Jaime Sanz

2020

doi: 10.1007/s00277-020-04317-7

Post-transplant cyclophosphamide for GVHD prophylaxis compared to ATG-based prophylaxis in unrelated donor transplantation

Bailén R, Kwon M, Pascual-Cascón MJ, Ferrà C, Sanz J, Gallardo-Morillo A, García-Sola A, Torrent A, Jiménez-Lorenzo MJ, Piñana JL, Montoro J, Oarbeascoa G, Dorado N, Gómez-Centurión I, Muñoz C, Martínez-Laperche C, Anguita J, Buño I, Díez-Martín JL; Grupo Español de Trasplante Hematopoyético y Terapia Celular (GETH).

2020

doi: 10.1080/10428194.2020.1839650.

Impact of combinations of single-nucleotide polymorphisms of anthracycline transporter genes upon the efficacy and toxicity of induction chemotherapy in acute myeloid leukemia

Megías-Vericat JE, Martínez-Cuadrón D, Herrero MJ, Rodríguez-Veiga R, Solana-Altabella A, Boluda B, Ballesta-López O, Cano I, Acuña-Cruz E, Cervera J, Poveda JL, Sanz M, Aliño SF, Montesinos P.

2020

doi: 10.3324/haematol.2020.263806

Networking for advanced molecular diagnosis in acute myeloid leukemia patients is possible: the PETHEMA NGS-AML project

Sargas C, Ayala R, Chillón MC, Larráyoz MJ, Carrillo-Cruz E, Bilbao C, Yébenes-Ramírez M, Llop M, Rapado I, García-Sanz R, Vázquez I, Soria E, Florido-Ortega Y, Janusz K, Botella C, Serrano J, Martínez-Cuadrón D, Bergua J, Amigo ML, Martínez-Sánchez P, Tormo M, Bernal T, Herrera-Puente P, García R, Algarra L, Sayas MJ, Costilla-Barriga L, Pérez-Santolalla E, Marchante I, Lavilla-Rubira E, Noriega V, Alonso-Domínguez JM, Sanz MÁ, Sánchez-Garcia J, Gómez-Casares MT, Pérez-Simón JA, Calasanz MJ, González-Díaz M, Martínez-López J, Barragán E, Montesinos P

2020

doi: 10.3390/jpm10040244.

Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia

Vega-Garcia N, Benito R, Esperanza-Cebollada E, Llop M, Robledo C, Vicente-Garcés C, Alonso J, Barragán E, Fernández G, Hernández-Sánchez JM, Martín-Izquierdo M, Maynou J, Minguela A, Montaño A, Ortega M, Torrebadell M, Cervera J, Sánchez J, Jiménez-Velasco A, Riesco S, Hernández-Rivas JM, Lassaletta Á, Fernández JM, Rives S, Dapena JL, Ramírez M, Camós M, On Behalf Of The Group Of Leukemia Of The Spanish Society Of Pediatric Hematology And Oncology Sehop.

2020

doi: 10.1111/cge.13879

Genotype FBN1/phenotype relationship in a cohort of patients with Marfan syndrome

Amparo Hernándiz Angel Zúñiga Francisco Valera Diana Domingo Imelda Ontoria‐Oviedo Jose F. Marí Jose A. Román Inmaculada Calvo Beatriz Insa Rosa Gómez José V. Cervera Manuel Miralles Jose A. Montero Luis Martínez‐Dolz Pilar Sepúlveda

2020

doi: 10.3390/genes11121434.

TYK2 Variants in B-Acute Lymphoblastic Leukaemia

urrubiartes-Martínez E, Bodega-Mayor I, Delgado-Wicke P, Molina-Jiménez F, Casique-Aguirre D, González-Andrade M, Rapado I, Camós M, Díaz-de-Heredia C, Barragán E, Ramírez-Orellana M, Aguado B, Figuera Á, Martínez-López J, Fernández-Ruiz E.

2020

doi: 10.1111/ejh.13529

Ex vivo T-cell depletion versus post-transplant cyclophosphamide, sirolimus, and mycophenolate mofetil as GVHD prophylaxis for allo-HSCT

Montoro J, Roldán E, Piñana JL, Barba P, Chorão P, Quintero A, Hernani R, Ortí G, Lorenzo JI, Balaguer-Roselló A, Salamero O, Fox L, Solves P, Gómez I, Guerreiro M, Hernández Boluda JC, Sanz G, Solano C, Sanz MÁ, Valcárcel D, Sanz J.

2020

doi: 10.17235/reed.2020.6895/2020

Management of chronic liver disease-associated severe thrombocytopenia in Spain: a view from the experts

Calleja-Panero JL, Andrade RJ, Bañares R, Crespo J, Esteban R, Jarque I, Mingot-Castellano ME, Romero-Gómez M, Muñoz-Peñín R, Bentley R, Shepherd J, Gil Aguirre A.

2020

doi: 10.1111/ejh.13529

Ex vivo T-cell depletion vs post-transplant cyclophosphamide, sirolimus, and mycophenolate mofetil as graft-vs-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation

Montoro J, Roldán E, Piñana JL, Barba P, Chorão P, Quintero A, Hernani R, Ortí G, Lorenzo JI, Balaguer-Roselló A, Salamero O, Fox L, Solves P, Gómez I, Guerreiro M, Hernández Boluda JC, Sanz G, Solano C, Sanz MÁ, Valcárcel D, Sanz J.

2020

doi: 10.1038/s41375-020-01058-4

Evolving treatment patterns and outcomes in older patients (≥60 years) with AML: changing everything to change nothing?

Martínez-Cuadrón D, Serrano J, Gil C, Tormo M, Martínez-Sánchez P, Pérez-Simón JA, García-Boyero R, Rodríguez-Medina C, López-Pavía M, Benavente C, Bergua J, Lavilla-Rubira E, Amigo ML, Herrera P, Alonso-Domínguez JM, Bernal T, Colorado M, Sayas MJ, Algarra L, Vidriales MB, Rodríguez-Macías G, Vives S, Pérez-Encinas MM, López A, Noriega V, García-Fortes M, Ramos F, Rodríguez-Gutiérrez JI, Costilla-Barriga L, Labrador J, Boluda B, Rodríguez-Veiga R, Martínez-López J, Sanz MA, Montesinos P.

2020

doi: 10.1186/s13045-020-00975-2

Prevention, recognition, and management of adverse events associated with gemtuzumab ozogamicin use in acute myeloid leukemia

Cortes JE, de Lima M, Dombret H, Estey EH, Giralt SA, Montesinos P, Röllig C, Venditti A, Wang ES.

2020

doi: 10.3390/cancers12113134.

Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia

Weinhäuser I, Pereira-Martins DA, Ortiz C, Silveira DR, Simões LAA, Bianco TM, Araujo CL, Koury LC, Melo RAM, Bittencourt RI, Pagnano K, Pasquini R, Nunes EC, Fagundes EM, Gloria AB, Kerbauy F, Chauffaille ML, Keating A, Tallman MS, Ribeiro RC, Dillon R, Ganser A, Löwenberg B, Valk P, Lo-Coco F, Sanz MA, Berliner N, Ammatuna E, Lucena-Araujo AR, Schuringa JJ, Rego EM.

2020

doi: 10.1182/blood.2020006731

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard and high risk myeloma

Goicoechea I, Puig N, Cedena MT, Burgos L, Cordón L, Vidriales MB, Flores-Montero J, Gutierrez N, Calasanz MJ, Martin Ramos ML, Lara-Astiaso D, Vilas-Zornoza A, Alignani D, Rodriguez I, Sarvide S, Alameda D, Garcés JJG, Rodríguez S, Fresquet VJ, Celay J, Garcia-Sanz R, Martinez-Lopez J, Oriol A, Rios R, Martín Sánchez J, Martinez R, Sarra J, Hernandez MT, de la Rubia J, Krsnik I, Moraleda JM, Palomera L, Bargay J, Martinez-Climent JA, Orfao A, Rosiñol L, Mateos MV, Lahuerta JJ, Bladé J, San Miguel J, Paiva B.

2020

doi: 10.1038/s41375-020-01022-2.

Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome

Hoeks M, Bagguley T, van Marrewijk C, Smith A, Bowen D, Culligan D, Kolade S, Symeonidis A, Garelius H, Spanoudakis M, Langemeijer S, Roelofs R, Wiegerinck E, Tatic A, Killick S, Panagiotidis P, Stanca O, Hellström-Lindberg E, Cermak J, van der Klauw M, Wouters H, van Kraaij M, Blijlevens N, Swinkels DW, de Witte T; EUMDS Registry Participants (Guillermo Sanz. et al)

2020

doi: 10.3324/haematol.2020.266817

Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective

Theo de Witte, Luca Malcovati, Pierre Fenaux, David Bowen, Argiris Symeonidis, Moshe Mittelman, Reinhard Stauder, Guillermo Sanz, Jaroslav Čermák, Saskia Langemeijer, Eva Hellström-Lindberg, Ulrich Germing, Mette Skov Holm, Krzysztof Mądry, Aurelia Tatic, António Medina Almeida, Aleksandar Savic, Inga Mandac Rogulj, Raphael Itzykson, Marlijn Hoeks, Hege Gravdahl Garelius, Dominic Culligan, Ioannis Kotsianidis, Lionel Ades, Arjan A. Van de Loosdrecht, Corine van Marrewijk, Ge Yu, Simon Crouch, Alex Smith

2020

doi: 10.2217/fon-2020-0700

Gilteritinib use in the treatment of relapsed or refractory acute myeloid leukemia with a FLT3 mutation

Octavio Ballesta-López , Antonio Solana-Altabella , Juan Eduardo Megías-Vericat , David Martínez-Cuadrón & Pau Montesinos

2020

doi: 10.1080/17474086.2020.1818559

Precision medicine in acute myeloid leukemia: where are we now and what does the future hold?

Megías-Vericat JE, Martínez-Cuadrón D, Solana-Altabella A, Montesinos P.

2020

doi: 10.1016/j.bcmd.2020.102505

A decade of changes in management of immune thrombocytopenia, with special focus on elderly patients

Lozano ML, Mingot-Castellano ME, Perera MM, Jarque I, Campos-Alvarez RM, González-López TJ, Carreño-Tarragona G, Bermejo N, Lopez-Fernandez MF, de Andrés A, Valcarcel D, Casado-Montero LF, Alvarez-Roman MT, Orts MI, Novelli S, González-Porras JR, Bolaños E, López-Ansoar E, Orna-Montero E, Vicente V. A decade of changes in management of immune thrombocytopenia, with special focus on elderly patients.

2020

doi: 10.1007/s15010-020-01521-5

Recommendations for screening, monitoring, prevention, and prophylaxis of infections in adult and pediatric patients receiving CAR T-cell therapy: a position paper

Los-Arcos I, Iacoboni G, Aguilar-Guisado M, Alsina-Manrique L, Díaz de Heredia C, Fortuny-Guasch C, García-Cadenas I, García-Vidal C, González-Vicent M, Hernani R, Kwon M, Machado M, Martínez-Gómez X, Maldonado VO, Pla CP, Piñana JL, Pomar V, Reguera-Ortega JL, Salavert M, Soler-Palacín P, Vázquez-López L, Barba P, Ruiz-Camps I. Recommendations for screening, monitoring, prevention, and prophylaxis of infections in adult and pediatric patients receiving CAR T-cell therapy: a position paper. Infection. 2020 Sep 26:1–17. doi: 10.1007/s15010-020-01521-5. Epub ahead of print. PMID: 32979154; PMCID: PMC7518951.

2020

2020

doi: 10.1158/1078-0432.CCR-20-3134

Evaluation of Trends and Prognosis Over Time in Patients with AML Relapsing After Allogeneic Hematopoietic Cell Transplant Reveals Improved Survival for Young Patients in Recent Years

Bazarbachi A, Schmid C, Labopin M, Beelen D, Wolfgang Blau I, Potter V, Niittyvuopio R, Socié G, Blaise D, Sanz J, Ciceri F, Abou Dalle I, Spyridonidis A, Bug G, Esteve J, Savani BN, Nagler A, Mohty M.

2020

doi: 10.1111/ejh.13417

Acute Myeloid Leukemia With inv(3)(q21.3q26.2)/t(3;3)(q21.3;q26.2): Study of 61 Patients Treated With Intensive Protocols

Sitges M, Boluda B, Garrido A, Morgades M, Granada I, Barragan E, Arnan M, Serrano J, Tormo M, Miguel Bergua J, Colorado M, Salamero O, Esteve J, Benavente C, Pérez-Encinas M, Coll R, Martí-Tutusaus JM, Brunet S, Sierra J, Ángel Sanz M, Montesinos P, Ribera JM, Vives S; PETHEMA, CETLAM cooperative groups.

2020

doi: 10.1038/s41591-020-1008-z

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Bernard E, Nannya Y, Hasserjian RP, Devlin SM, Tuechler H, Medina-Martinez JS, Yoshizato T, Shiozawa Y, Saiki R, Malcovati L, Levine MF, Arango JE, Zhou Y, Solé F, Cargo CA, Haase D, Creignou M, Germing U, Zhang Y, Gundem G, Sarian A, van de Loosdrecht AA, Jädersten M, Tobiasson M, Kosmider O, Follo MY, Thol F, Pinheiro RF, Santini V, Kotsianidis I, Boultwood J, Santos FPS, Schanz J, Kasahara S, Ishikawa T, Tsurumi H, Takaori-Kondo A, Kiguchi T, Polprasert C, Bennett JM, Klimek VM, Savona MR, Belickova M, Ganster C, Palomo L, Sanz G, Ades L, Della Porta MG, Smith AG, Werner Y, Patel M, Viale A, Vanness K, Neuberg DS, Stevenson KE, Menghrajani K, Bolton KL, Fenaux P, Pellagatti A, Platzbecker U, Heuser M, Valent P, Chiba S, Miyazaki Y, Finelli C, Voso MT, Shih LY, Fontenay M, Jansen JH, Cervera J, Atsuta Y, Gattermann N, Ebert BL, Bejar R, Greenberg PL, Cazzola M, Hellström-Lindberg E, Ogawa S, Papaemmanuil E

2020

doi: 10.1111/tid.13440

Cytomegalovirus DNA load monitoring in stool specimens for anticipating the occurrence of intestinal acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation: Is it of any value?

Bueno F, Albert E, Giménez E, Piñana JL, Pérez A, Gómez MD, Hernández-Boluda JC, Gonzalez-Barberá EM, Montoro J, Guerreiro M, Balaguer-Roselló A, Hernani R, Sanz J, Solano C, Navarro D.

2020

doi: 10.1038/s41408-020-00352-9

Characterization of FLT3-ITDmut acute myeloid leukemia: molecular profiling of leukemic precursor cells

Serena Travaglini, Daniela Francesca Angelini, Valentina Alfonso, Gisella Guerrera, Serena Lavorgna, Mariadomenica Divona, Anna Maria Nardozza, Maria Irno Consalvo, Emiliano Fabiani, Marco De Bardi, Benedetta Neri, Fabio Forghieri, Francesco Marchesi, Giovangiacinto Paterno, Raffaella Cerretti, Eva Barragan, Valentina Fiori, Sabrina Dominici, Maria Ilaria Del Principe, Adriano Venditti, Luca Battistini, William Arcese, Francesco Lo-Coco, Maria Teresa Voso & Tiziana Ottone

2020

doi: 10.1111/bjh.17019

Male genital GvHD: a hidden complication following haematopoietic stem cell transplantation

Montoro J, Chorão P, Quintero A, Roca J, Guerreiro M, Balaguer-Roselló A.

2020

doi: 10.1186/s13045-020-00923-0.

Post-transplant cyclophosphamide versus antithymocyte globulin in patients with acute myeloid leukemia in first complete remission undergoing allogeneic stem cell transplantation from 10/10 HLA-matched unrelated donors

Brissot E, Labopin M, Moiseev I, Cornelissen JJ, Meijer E, Van Gorkom G, Rovira M, Ciceri F, Griskevicius L, Blaise D, Forcade E, Mistrik M, Mielke S, Bulabois CE, Niittyvuopio R, Deconinck E, Ruggeri A, Sanz J, Spyridonidis A, Savani B, Giebel S, Nagler A, Mohty M.

2020

doi: 10.1080/10428194.2020.1788015

Feasibility of thiotepa addition to the fludarabine-busulfan conditioning with tacrolimus/sirolimus as graft vs host disease prophylaxis

Fox ML, García-Cadenas I, Pérez AM, Villacampa G, Piñana JL, Ortí G, Montoro J, Roldán E, Bosch Vilaseca A, Martino R, Salamero O, Saavedra S, Hernandez-Boluda JC, Esquirol A, Sierra J, Sanz J, Solano C, Bosch F, Barba P, Valcarcel D.

2020

doi: 10.1186/s13045-020-00929-8

Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy

Cortes JE, Heidel FH, Fiedler W, Smith BD, Robak T, Montesinos P, Candoni A, Leber B, Sekeres MA, Pollyea DA, Ferdinand R, Ma WW, O'Brien T, O'Connell A, Chan G, Heuser M.

2020

doi: 10.1007/s00277-020-04186-0

Drug-drug interactions of newly approved small molecule inhibitors for acute myeloid leukemia

Megías-Vericat JE, Solana-Altabella A, Ballesta-López O, Martínez-Cuadrón D, Montesinos P.

2020

doi: 10.1038/s41409-020-01005-y

Measurable residual disease (MRD) testing for acute leukemia in EBMT transplant centers: a survey on behalf of the ALWP of the EBMT

Nagler A, Baron F, Labopin M, Polge E, Esteve J, Bazarbachi A, Brissot E, Bug G, Ciceri F, Giebel S, Gilleece MH, Gorin NC, Lanza F, Peric Z, Ruggeri A, Sanz J, Savani BN, Schmid C, Shouval R, Spyridonidis A, Versluis J, Mohty M.

2020

doi: 10.1016/j.bbmt.2020.07.022

Predicting Survival after Allogeneic Hematopoietic Cell Transplantation in Myelofibrosis: Performance of the Myelofibrosis Transplant Scoring System (MTSS) and Development of a New Prognostic Mode

Hernández-Boluda JC, Pereira A, Alvarez-Larran A, Martín AA, Benzaquen A, Aguirre L, Mora E, González P, Mora J, Dorado N, Sampol A, García-Gutiérrez V, López-Godino O, Fox ML, Reguera JL, Pérez-Encinas M, Pascual MJ, Xicoy B, Parody R, González-Pinedo L, Español I, Avendaño A, Correa JG, Vallejo C, Jurado M, García-Cadenas I, Osorio S, Durán MA, Sánchez-Guijo F, Cervantes F, Piñana JL.

2020

doi: 10.1016/j.bbmt.2020.06.028

Predicting Mortality after Autologous Transplant: Development of a Novel Risk Score

Berro M, Chhabra S, Piñana JL, Arbelbide J, Rivas MM, Basquiera AL, Vitriu A, Requejo A, Milovic V, Yantorno S, Bentolila G, Garcia JJ, Castro M, Palmer S, Saslavsky M, Duarte P, Cerutti A, Jarchum G, Tisi Baña M, Thapa B, Solano C, Sureda A, Rovira M, Shaw BE, Kusminsky G; Grupo Argentino de Trasplante de Médula Ósea y Terapia Celular (GATMO-TC).

2020

doi: 10.3324/haematol.2019.223925

Obesity is a risk factor for acute promyelocytic leukemia: evidence from population and cross-sectional studies studies and correlation with flt3 mutations and polyunsaturated fatty acid metabolism.

Mazzarella L, Botteri E, Matthews A, Gatti E, Di Salvatore D, Bagnardi V, Breccia M, Montesinos P, Bernal T, Gil C, Ley TJ, Sanz M, Bhaskaran K, Lo Coco F, Pelicci PG

2020

doi: 10.3324/haematol.2019.243410

Clinical Practice Recommendation on Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia Patients With FLT3-internal Tandem Duplication: A Position Statement From the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Bazarbachi A, Bug G, Baron F, Brissot E, Ciceri F, Dalle IA, Döhner H, Esteve J, Floisand Y, Giebel S, Gilleece M, Gorin NC, Jabbour E, Aljurf M, Kantarjian H, Kharfan-Dabaja M, Labopin M, Lanza F, Malard F, Peric Z, Prebet T, Ravandi F, Ruggeri A, Sanz J, Schmid C, Shouval R, Spyridonidis A, Versluis J, Vey N, Savani BN, Nagler A, Mohty M.

2020

doi: 10.1038/s41409-020-0970-x

Management of Patients With Acute Leukemia During the COVID-19 Outbreak: Practical Guidelines From the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Brissot E, Labopin M, Baron F, Bazarbachi A, Bug G, Ciceri F, Esteve J, Giebel S, Gilleece MH, Gorin NC, Lanza F, Peric Z, Ruggeri A, Sanz J, Savani BN, Schmid C, Shouval R, Spyridonidis A, Versluis J, Nagler A, Mohty M.

2020

2020

2020

doi: 10.1016/S2352-3026(20)30205-2

Special Considerations in the Management of Adult Patients With Acute Leukaemias and Myeloid Neoplasms in the COVID-19 Era: Recommendations From a Panel of International Experts

Zeidan AM, Boddu PC, Patnaik MM, Bewersdorf JP, Stahl M, Rampal RK, Shallis R, Steensma DP, Savona MR, Sekeres MA, Roboz GJ, DeAngelo DJ, Schuh AC, Padron E, Zeidner JF, Walter RB, Onida F, Fathi A, DeZern A, Hobbs G, Stein EM, Vyas P, Wei AH, Bowen DT, Montesinos P, Griffiths EA, Verma AK, Keyzner A, Bar-Natan M, Navada SC, Kremyanskaya M, Goldberg AD, Al-Kali A, Heaney ML, Nazha A, Salman H, Luger S, Pratz KW, Konig H, Komrokji R, Deininger M, Cirici BX, Bhatt VR, Silverman LR, Erba HP, Fenaux P, Platzbecker U, Santini V, Wang ES, Tallman MS, Stone RM, Mascarenhas J.

2020

doi: 10.1038/s41409-020-0803-y

Redefining and Measuring Transplant Conditioning Intensity in Current Era: A Study in Acute Myeloid Leukemia Patients

Spyridonidis A, Labopin M, Savani BN, Niittyvuopio R, Blaise D, Craddock C, Socié G, Platzbecker U, Beelen D, Milpied N, Cornelissen JJ, Ganser A, Huynh A, Griskevicius L, Giebel S, Aljurf M, Brissot E, Malard F, Esteve J, Peric Z, Baron F, Ruggeri A, Schmid C, Gilleece M, Gorin NC, Lanza F, Shouval R, Versluis J, Bug G, Fløisand Y, Ciceri F, Sanz J, Bazarbachi A, Nagler A, Mohty M.

2020

doi: 10.1038/s41409-020-0835-3

Correction: Redefining and Measuring Transplant Conditioning Intensity in Current Era: A Study in Acute Myeloid Leukemia Patients

Spyridonidis A, Labopin M, Savani BN, Niittyvuopio R, Blaise D, Craddock C, Socié G, Platzbecker U, Beelen D, Milpied N, Cornelissen JJ, Ganser A, Huynh A, Griskevicius L, Giebel S, Aljurf M, Brissot E, Malard F, Esteve J, Peric Z, Baron F, Ruggeri A, Schmid C, Gilleece M, Gorin NC, Lanza F, Shouval R, Versluis J, Bug G, Fløisand Y, Ciceri F, Sanz J, Bazarbachi A, Nagler A, Mohty M.

2020

doi: 10.1038/s41375-020-0917-7

Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification-an approach to classification of patients with t-MDS

Kuendgen A, Nomdedeu M, Tuechler H, Garcia-Manero G, Komrokji RS, Sekeres MA, Della Porta MG, Cazzola M, DeZern AE, Roboz GJ, Steensma DP, Van de Loosdrecht AA, Schlenk RF, Grau J, Calvo X, Blum S, Pereira A, Valent P, Costa D, Giagounidis A, Xicoy B, Döhner H, Platzbecker U, Pedro C, Lübbert M, Oiartzabal I, Díez-Campelo M, Cedena MT, Machherndl-Spandl S, López-Pavía M, Baldus CD, Martinez-de-Sola M, Stauder R, Merchan B, List A, Ganster C, Schroeder T, Voso MT, Pfeilstöcker M, Sill H, Hildebrandt B, Esteve J, Nomdedeu B, Cobo F, Haas R, Sole F, Germing U, Greenberg PL, Haase D, Sanz G.

2020

doi: 10.1111/ajt.16147

Cytomegalovirus DNAemia and risk of mortality in allogeneic hematopoietic stem cell transplantation: Analysis from the Spanish Hematopoietic Transplantation and Cell Therapy Group

Carlos Solano Lourdes Vázquez Estela Giménez Rafael de la Cámara Eliseo Albert Montserrat Rovira Ildefonso Espigado Carmen M. Calvo Javier López‐Jiménez María Suárez‐Lledó Anabella Chinea Albert Esquirol Ariadna Pérez Aránzazu Bermúdez Raquel Saldaña Inmaculada Heras Ana J. González‐Huerta Tamara Torrado Guiomar Bautista Montserrat Batlle Santiago Jiménez Carlos Vallejo Pere Barba María Á. Cuesta José L. Piñana David Navarro

2020

doi: 10.1038/s41409-020-0921-6

Uniform graft-versus-host disease prophylaxis with posttransplant cyclophosphamide, sirolimus, and mycophenolate mofetil following hematopoietic stem cell transplantation from haploidentical, matched sibling and unrelated donors

Montoro J, Piñana JL, Hernández-Boluda JC, Hernani R, Lorenzo I, Pérez A, Guerreiro M, Balaguer-Rosello A, Sanz GF, Carretero C, Albert E, Navarro D, Sanz MA, Solano C, Sanz J.

2020

doi: 10.1038/s41409-020-0943-0

Community acquired respiratory virus infections in adult patients undergoing umbilical cord blood transplantation

Juan Montoro, Jaime Sanz, Ignacio Lorenzo, Aitana Balaguer-Roselló, Miguel Salavert, María Dolores Gómez, Manuel Guerreiro, Eva M. González Barberá, Cristina Aguado, Luiza Tofán, Guillermo F. Sanz, Miguel A. Sanz & José Luis Piñana

2020

doi: 10.1186/s13045-020-00882-6

Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia: a comparative study of the ALWP EBMT

Sanz J, Galimard JE, Labopin M, Afanasyev B, Angelucci E, Ciceri F, Blaise D, Cornelissen JJ, Meijer E, Diez-Martin JL, Koc Y, Rovira M, Castagna L, Savani B, Ruggeri A, Nagler A, Mohty M; Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT). Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia: a comparative study of the ALWP EBMT. J Hematol Oncol. 2020 May 6;13(1):46. doi: 10.1186/s13045-020-00882-6. PMID: 32375860; PMCID: PMC7201995.

2020

doi: 10.1111/tid.13301

Assessment of Immunodeficiency Scoring Index Performance in Enterovirus/Rhinovirus Respiratory Infection After Allogeneic Hematopoietic Stem Cell Transplantation

Pérez A, Montoro J, Hernani R, Lorenzo I, Hernández-Boluda JC, Giménez E, Gómez MD, Balaguer-Roselló A, Gonzalez-Barberá E, Guerreiro M, Aguilar C, Navarro D, Solano C, Sanz J, Piñana JL

2020

doi: 10.1016/j.bbmt.2020.01.015

Features of Cytomegalovirus DNAemia Blips in Allogeneic Hematopoietic Stem Cell Transplant Recipients: Implications for Optimization of Preemptive Antiviral Therapy Strategies

Huntley D, Talaya A, Giménez E, Martínez A, Hernández-Boluda JC, Hernani R, Torres I, Alberola J, Albert E, Piñana JL, Solano C, Navarro D

2020

doi: 10.1038/s41375-020-0849-2

Genomic characterization of patients with polycythemia vera developing resistance to hydroxyurea

Alvarez-Larrán A, Díaz-González A, Such E, Mora E, Andrade-Campos M, García-Hernández C, Gómez-Casares MT, García-Gutiérrez V, Carreño-Tarragona G, Garrote M, Fernández-Ibarrondo L, Cervera J, Bellosillo B, Cervantes F, Hernández-Boluda JC; MPN Spanish Group (GEMFIN).

2020

doi: 10.3390/cancers12051313

PLZF-RAR α, NPM1-RAR α, and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review

Sobas M, Talarn-Forcadell MC, Martínez-Cuadrón D, Escoda L, García-Pérez MJ, Mariz J, Mela-Osorio MJ, Fernández I, Alonso-Domínguez JM, Cornago-Navascués J, Rodríguez-Macias G, Amutio ME, Rodríguez-Medina C, Esteve J, Sokół A, Murciano-Carrillo T, Calasanz MJ, Barrios M, Barragán E, Sanz MA, Montesinos P.

2020

doi: 10.1038/s41409-020-0950-1

Peripheral Blood Regulatory T Cells and Occurrence of Cytomegalovirus DNAemia After Unmanipulated Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Posttransplant Cyclophosphamide

Huntley D, Giménez E, Pascual MJ, Vázquez L, Amat P, Remigia MJ, Hernández M, Hernández-Boluda JC, Gago B, Piñana JL, García M, Pérez A, Alberola J, Gozalbo-Rovira R, Albert E, Solano C, Navarro D

2020

doi: 10.1111/bjh.16654

Development of a core outcome set for myelodysplasticsyndromes – a Delphi study from the EUMDS RegistryGroup

Rochau U, Stojkov I, Conrads-Frank A, Borba HH, Koinig KA, Arvandi M, van Marrewijk C, Garelius H, Germing U, Symeonidis A, Sanz GF, Fenaux P, de Witte T, Efficace F, Siebert U, Stauder R.

2020

doi: 10.1038/s41598-020-61589-9

Analysis of SNP Array Abnormalities in Patients with DE NOVO Acute Myeloid Leukemia with Normal Karyotype

Ibáñez M, Such E, Onecha E, Gómez-Seguí I, Liquori A, Sellés J, Hervás-Marín D, Barragán E, Ayala R, LLop M, López-Pavía M, Rapado I, Neef A, Sanjuan-Pla A, Sargas C, Gonzalez-Romero E, Boluda-Navarro M, Andreu R, Senent L, Montesinos P, Martínez-López J, Angel Sanz M, Sanz G, Cervera J

2020

doi: 10.3390/ijms21082714.

MTHFR and VDR Polymorphisms Improve the Prognostic Value of MYCN Status on Overall Survival in Neuroblastoma Patients.

Olivera GG, Yáñez Y, Gargallo P, Sendra L, Aliño SF, Segura V, Sanz MÁ, Cañete A, Castel V, Font De Mora J, Hervás D, Berlanga P, Herrero MJ

2020

doi: 10.1038/s41375-020-0815-

Determinants of survival in myelofibrosis patients undergoing allogeneic hematopoietic cell transplantation

Hernández-Boluda JC, Pereira A, Kröger N, Beelen D, Robin M, Bornhäuser M, Angelucci E, Vitek A, Blau IW, Niittyvuopio R, Finke J, Cornelissen JJ, Passweg J, Dreger P, Petersen E, Kanz L, Sanz J, Zuckerman T, Zinger N, Iacobelli S, Hayden P, Czerw T, McLornan D, Yakoub-Agha I

2020

doi: 10.3324/haematol.2018.211904.

Daratumumab Displays in Vitro and in Vivo Anti-Tumor Activity in Models of B-cell non-Hodgkin Lymphoma and Improves Responses to Standard Chemo-Immunotherapy Regimens

Vidal-Crespo A, Matas-Céspedes A, Rodriguez V, Rossi C, Valero JG, Serrat N, Sanjuan-Pla A, Menéndez P, Roué G, López-Guillermo A, Giné E, Campo E, Colomer D, Bezombes C, van Bueren JL, Chiu C, Doshi P, Pérez-Galán P

2020

doi: 10.1056/NEJMoa1917635

Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease

Zeiser R, von Bubnoff N, Butler J, Mohty M, Niederwieser D, Or R, Szer J, Wagner EM, Zuckerman T, Mahuzier B, Xu J, Wilke C, Gandhi KK, Socié G; REACH2 Trial Group. Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease.

2020

2020

doi: 10.1111/bjh.16175

Spanish Guidelines for the use of targeted deep sequencing in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

Palomo L, Ibáñez M, Abáigar M, Vázquez I, Álvarez S, Cabezón M, Tazón-Vega B, Rapado I, Fuster-Tormo F, Cervera J, Benito R, Larrayoz MJ, Cigudosa JC, Zamora L, Valcárcel D, Cedena MT, Acha P, Hernández-Sánchez JM, Fernández-Mercado M, Sanz G, Hernández-Rivas JM, Calasanz MJ, Solé F, Such E; Spanish Group of MDS (GESMD).

2020

doi: 10.1111/ejh.13346

Characteristics and outcome of adult patients with acute promyelocytic leukemia and increased body mass index treated with the PETHEMA Protocols

Sobas M, Rodriguez-Veiga R, Vellenga E, Paluszewska M, De la Serna J, García-Álvarez F, Gil C, Brunet S, Bergua J, González-Campos J, Ribera JM, Tormo M, González M, Fernández I, Benavente C, González-Sanmiguel JD, Esteve J, Pérez-Encinas M, Salamero O, Manso F, Lowenberg B, Sanz MA, Montesinos P

2020

doi: 10.1038/s41375-020-0773-5

Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study

Montesinos P, Roboz GJ, Bulabois CE, Subklewe M, Platzbecker U, Ofran Y, Papayannidis C, Wierzbowska A, Shin HJ, Doronin V, Deneberg S, Yeh SP, Ozcan MA, Knapper S, Cortes J, Pollyea DA, Ossenkoppele G, Giralt S, Döhner H, Heuser M, Xiu L, Singh I, Huang F, Larsen JS, Wei AH

2020

doi: 10.1016/j.blre.2020.100675

Tyrosine kinase inhibitors for acute myeloid leukemia: A step toward disease control?

Megías-Vericat JE, Ballesta-López O, Barragán E, Martínez-Cuadrón D, Montesinos P

2020

doi: 10.1038/s41375-020-0783-3

Management of hyperleukocytosis and impact of leukapheresis among patients with acute myeloid leukemia (AML) on short- and long-term clinical outcomes: a large, retrospective, multicenter, international study

Stahl M, Shallis RM, Wei W, Montesinos P, Lengline E, Neukirchen J, Bhatt VR, Sekeres MA, Fathi AT, Konig H, Luger S, Khan I, Roboz GJ, Cluzeau T, Martínez-Cuadron D, Raffoux E, Germing U, Umakanthan JM, Mukherjee S, Brunner AM, Miller A, McMahon CM, Ritchie EK, Rodríguez-Veiga R, Itzykson R, Boluda B, Rabian F, Tormo M, Acuña-Cruz E, Rabinovich E, Yoo B, Cano I, Podoltsev NA, Bewersdorf JP, Gore S, Zeidan AM

2020

doi: 10.1038/s41409-020-0865-x

Reconstitution of cytomegalovirus-specific T-cell immunity following unmanipulated haploidentical allogeneic hematopoietic stem cell transplantation with posttransplant cyclophosphamide

Huntley D, Giménez E, Pascual MJ, Remigia MJ, Amat P, Vázquez L, Hernández M, Hernández-Boluda JC, Gago B, Piñana JL, García M, Martínez A, Mateo E, Gozalbo-Rovira R, Albert E, Solano C, Navarro D

2020

doi: 10.1200/JCO.19.01231

Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma

Paiva B, Puig N, Cedena MT, Rosiñol L, Cordón L, Vidriales MB, Burgos L, Flores-Montero J, Sanoja-Flores L, Lopez-Anglada L, Maldonado R, de la Cruz J, Gutierrez NC, Calasanz MJ, Martin-Ramos ML, Garcia-Sanz R, Martinez-Lopez J, Oriol A, Blanchard MJ, Rios R, Martin J, Martinez-Martinez R, Sureda A, Hernandez MT, de la Rubia J, Krsnik I, Moraleda JM, Palomera L, Bargay J, Van Dongen JJM, Orfao A, Mateos MV, Blade J, San-Miguel JF, Lahuerta JJ; GEM (Grupo Español de Mieloma)/PETHEMA (Programa Para el Estudio de la Terapéutica en Hemopatías Malignas) Cooperative Study Group. Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma)

2020

doi: 10.3324/haematol.2018.212217

Impact of red blood cell transfusion dose density on progression-free survival in patients with lower-risk myelodysplastic syndromes

Louise de Swart Simon Crouch Marlijn Hoeks Alex Smith Saskia Langemeijer Pierre Fenaux Argiris Symeonidis Jaroslav Cermâk Eva Hellström-Lindberg Reinhard Stauder Guillermo Sanz Moshe Mittelman Mette Skov Holm Luca Malcovati Krzysztof Mądry Ulrich Germing Aurelia Tatic Aleksandar Savic Antonio Medina Almeida Njetocka Gredelj-Simec Agnes Guerci-Bresler Odile Beyne-Rauzy Dominic Culligan Ioannis Kotsianidis Raphael Itzykson Corine van Marrewijk Nicole Blijlevens David Bowen Theo de Witte on behalf of the EUMDS Registry Participants

2020

doi: 10.3324/haematol.2018.212332

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry

Hoeks M, Yu G, Langemeijer S, Crouch S, de Swart L, Fenaux P, Symeonidis A, Čermák J, Hellström-Lindberg E, Sanz G, Stauder R, Holm MS, Mittelman M, Mądry K, Malcovati L, Tatic A, Almeida AM, Germing U, Savic A, Šimec NG, Culligan D, Itzykson R, Guerci-Bresler A, Slama B, Droste J, van Marrewijk C, van de Loosdrecht A, Blijlevens N, van Kraaij M, Bowen D, de Witte T, Smith A; EUMDS Registry Participants.

2020

doi: 10.1038/s41409-019-0698-7

The effect of timing on community acquired respiratory virus infection mortality during the first year after allogeneic hematopoietic stem cell transplantation: a prospective epidemiological survey.

Piñana JL, Pérez A, Montoro J, Hernani R, Lorenzo I, Giménez E, Gómez MD(6), Guerreiro M(4), González-Barberá EM(6), Carretero C,Salavert M, Balaguer-Roselló A(4), Sanz G, Hernández-Boluda JC,Solano C, Sanz J, Navarro D

2020

doi: 10.1016/j.bbmt.2019.10.014

Prospective Randomized Study Comparing Myeloablative Unrelated Umbilical Cord Blood Transplantation versus HLA-Haploidentical Related Stem Cell Transplantation for Adults with Hematologic Malignancies

Sanz J, Montoro J, Solano C, Valcárcel D, Sampol A, Ferrá C, Parody R, Lorenzo I, Montesinos P, Ortí G, Hernández-Boluda JC, Balaguer-Roselló A, Guerreiro M, Carretero C, Sanz GF, Sanz MA, Piñana JL

2020

doi: 10.1016/j.clml.2019.09.616

Outcome of a Real-Life Population of Patients With Acute Promyelocytic Leukemia Treated According to the PETHEMA Guidelines: The Polish Adult Leukemia Group (PALG) Experience.

Sobas M, Czyż A, Montesinos P, Armatys A, Helbig G, Hołowiecka A, Pluta A, Zarzycka E, Piątkowska-Jakubas B, Majcherek M, Lewandowski K, Gołos A, Paluszewska M, Podhorecka M, Oleksiuk J, Skręt A, Hawrylecka D, Guzicka-Kazimierczak RE, Wątek M, Gromek T, Charliński G, Grosicki S, Holojda J, Miśkiewicz W, Martinez-Cuadrón D, Sanz MA, Wróbel T, Wierzbowska A, Giebel S.

2020

doi: 10.1002/cam4.2814

A pediatric regimen for adolescents and young adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: Results of the ALLRE08 PETHEMA trial

Ribera JM, Morgades M, Montesinos P, Tormo M, Martínez-Carballeira D, González-Campos J, Gil C, Barba P, García-Boyero R, Coll R, Pedreño M, Ribera J, Mercadal S, Vives S, Novo A, Genescà E, Hernández-Rivas JM, Bergua J, Amigo ML, Vall-Llovera F, Martínez-Sánchez P, Calbacho M, García-Cadenas I, Garcia-Guiñon A, Sánchez-Sánchez MJ, Cervera M, Feliu E, Orfao A; PETHEMA Group, Spanish Society of Hematolog

2020

doi: 10.1038/s41375-020-0728-x

Impact of somatic mutations in myelodysplastic patients with isolated partial or total loss of chromosome 7

Crisà E, Kulasekararaj AG, Adema V, Such E, Schanz J, Haase D, Shirneshan K, Best S, Mian SA, Kizilors A, Cervera J, Lea N, Ferrero D, Germing U, Hildebrandt B, Martínez ABV, Santini V, Sanz GF, Solé F, Mufti GJ

2020

doi: 10.1111/bjh.16432

Improving the prediction of acute myeloid leukaemia outcomes by complementing mutational profiling with ex vivo chemosensitivity

Onecha E, Ruiz-Heredia Y, Martínez-Cuadrón D, Barragán E, Martinez-Sanchez P, Linares M, Rapado I, Perez-Oteyza J, Magro E, Herrera P, Rojas JL, Gorrochategui J, Villoria J, Boluda B, Sargas C, Ballesteros J, Montesinos P, Martínez-López J, Ayala R

2020

doi: 10.1080/10428194.2020.1728753

Patterns of care and clinical outcomes of patients with newly diagnosed acute myeloid leukemia presenting with hyperleukocytosis who do not receive intensive chemotherapy

Shallis RM, Stahl M, Wei W, Montesinos P, Lengline E, Neukirchen J, Bhatt VR, Sekeres MA, Fathi AT, Konig H, Luger S, Khan I, Roboz GJ, Cluzeau T, Martínez-Cuadron D, Raffoux E, Germing U, Umakanthan JM, Mukhereje S, Brunner AM, Miller A, McMahon CM, Ritchie EK, Rodríguez-Veiga R, Itzykson R, Boluda B, Rabian F, Tormo M, Acuña-Cruz E, Rabinovich E, Yoo B, Cano I, Podoltsev NA, Bewersdorf JP, Gore S, Zeidan AM.

2020

doi: 10.1111/ejh.13370

Use of eltrombopag for patients 65 years old or older with immune thrombocytopenia

González-López TJ, Sánchez-González B, Jarque I, Bernat S, Fernández-Fuertes F, Caparrós I, Soto I, Fernández-Rodríguez A, Bolaños E, Pérez-Rus G, Pascual C, Hernández-Rivas JA, López-Ansoar E, Gómez-Nuñez M, Martínez-Robles V, Olivera P, Yera Cobo M, Peñarrubia MJ, Fernández-Miñano C, de Cabo E, Martínez Badas MP, Perdomo G, García-Frade LJ

2020

doi: 10.1038/s41375-020-0758-4

Outcome of older (≥70 years) APL patients frontline treated with or without arsenic trioxide-an International Collaborative Study

Kayser S, Rahmé R, Martínez-Cuadrón D, Ghiaur G, Thomas X, Sobas M, Guerci-Bresler A, Garrido A, Pigneux A, Gil C, Raffoux E, Tormo M, Vey N, de la Serna J, Salamero O, Lengfelder E, Levis MJ, Fenaux P, Sanz MA, Platzbecker U, Schlenk RF, Adès L, Montesinos P

2020

doi: 10.1111/tid.13206

Incidence, features and outcomes of Cytomegalovirus DNAemia in unmanipulated haploidentical allogeneic hematopoietic stem cell transplantation with post‐transplantation cyclophosphamide

Huntley D, Giménez E, Pascual MJ, Hernández-Boluda JC, Gago B, Vázquez L, Piñana JL, García M, Pérez A, Serrano D, Hernández M, Albert E, Solano C, Navarro D

2020

doi: 10.1016/j.bbmt.2020.02.003

Potential Survival Benefit for Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation After Nivolumab Therapy for Relapse/Refractory Hodgkin Lymphoma: Real-Life Experience in Spain

Martínez C, Carpio C, Heras I, Ríos-Herranz E, Buch J, Gutierrez A, Romero S, Zeberio I, García-García I, Rodriguez-Izquierdo A, Alonso R, Bargay J, Barrenetxea C, Domingo-Doménech E, de Haro ME, Palomera L, García-Sanz R; Spanish Group of Lymphoma and Bone Marrow Transplantation (GELTAMO).

2020

doi: 10.1038/s41409-019-0525-1

Daratumumab Is a Safe and Effective Rescue Therapy for Multiple Myeloma Patients Who Relapse After allo-HSCT

Gonzalez-Rodriguez AP, Lopez-Corral L, Fajardo DFM, Gonzalez-Huerta AJ, Palomo P, Bermudez A, Ripa TZ, Santos-Diaz P, Gonzalez-Muñiz S, Zanabilli J, Ubieto AJ, de Arriba F, Arnao-Herraiz M, Sordo-Bahamonde C, López-Soto A, Gonzalez S, Rosiñol L, Mateos MV.

2020

doi: 10.1016/j.bbmt.2019.08.020

Partial T Cell-Depleted Peripheral Blood Stem Cell Transplantation from HLA-Identical Sibling Donors for Patients with Severe Aplastic Anemia.

Sanz J, Moscardó F, Montoro J, Cano I, Guerreiro M, Dasí MA, Solves P, Lorenzo I, Gómez-Segui I, Montesinos P, Mora E, Arnao M, Sempere A, Jarque I, Carretero C, Senent L, Vicente A, Andreu R, Luna I, Balaguer-Roselló A, Carpio N, Sanz GF, Sanz MA, Piñana JL.

2020

doi: 10.1038/s41375-019-0534-5

Prognostic factors for adult single cord blood transplantation among European and Japanese populations: the Eurocord/ALWP-EBMT and JSHCT/JDCHCT collaborative study.

Kanda J, Hayashi H, Ruggeri A, Kimura F, Volt F, Takahashi S, Labopin M, Kako S, Tozatto-Maio K, Yano S, Sanz G, Uchida N, Van Lint MT, Kato S, Mohty M, Forcade E, Kanamori H, Sierra J, Ohno Y, Saccardi R, Fukuda T, Ichinohe T, Takanashi M, Rocha V, Okamoto S, Nagler A, Atsuta Y, Gluckman E.

2020

doi: 10.1016/j.jinf.2019.12.022

The clinical benefit of instituting a prospective clinical community-acquired respiratory virus surveillance program in allogeneic hematopoietic stem cell transplantation

Piñana J, Montoro J, Aznar C, Lorenzo I, Gómez M, Guerreiro M, Carretero C, González-Barberá E, Balaguer-Roselló A, Sanz R, Salavert M, Navarro D, Sanz M, Sanz G, Sanz J

2020

doi: 10.1182/blood.2019002697

Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia

Döhner K, Thiede C, Jahn N, Panina E, Gambietz A, Larson RA, Prior TW, Marcucci G, Jones D, Krauter J, Heuser M, Voso MT, Ottone T, Nomdedeu JF, Mandrekar SJ, Klisovic RB, Wei AH, Sierra J, Sanz MA, Brandwein JM, de Witte T, Jansen JH, Niederwieser D, Appelbaum FR, Medeiros BC, Tallman MS, Schlenk RF, Ganser A, Serve H, Ehninger G, Amadori S, Gathmann I, Benner A, Pallaud C, Stone RM, Döhner H, Bloomfield CD

2020

doi: 10.1128/AAC.01415-19

High Heterogeneity of Multidrug-Resistant Enterobacteriaceae Fecal Levels in Hospitalized Patients Is Partially Driven by Intravenous β-Lactams

Djukovic A, González-Barberá EM, Sanz J, Artacho A, Peñaranda I, Herrera B, Garzón MJ, Salavert M, López-Hontangas JL, Xavier KB, Kuster B, Debrauwer L, Rolain JM, Sanz MA, Xavier JB, Ubeda C.

2020

doi: 10.1016/j.medcli.2019.11.007

Clinico-biological characteristics of patients with myelofibrosis: an analysis of 1,000 cases from the Spanish Registry of Myelofibrosis.

Pastor-Galán I, Hernández-Boluda JC, Correa JG, Alvarez-Larrán A, Ferrer-Marín F, Raya JM, Ayala R, Velez P, Pérez-Encinas M, Estrada N, García-Gutiérrez V, Fox ML, Payer A, Kerguelen A, Cuevas B, Durán MA, Ramírez MJ, Gómez-Casares MT, Mata-Vázquez MI, Mora E, Martínez-Valverde C, Arbelo E, Angona A, Magro E, Antelo ML, Somolinos N, Cervantes F; en representación del Grupo Español de Enfermedades Mieloproliferativas Filadelfia Negativas (GEMFIN)

2020

doi: 10.1016/j.jinf.2020.01.001

Clinical significance of Pneumocystis jirovecii DNA detection by real-time PCR in hematological patient respiratory specimens

Piñana, J. L., Albert, E., Gómez, M. D., Pérez, A., Hernández-Boluda, J. C., Montoro, J., Salavert, M., González, E. M., Tormo, M., Giménez, E., Villalba, M., Balaguer-Roselló, A., Hernani, R., Bueno, F., Borrás, R., Sanz, J., Solano, C., & Navarro, D.

2020

doi: 10.1007/s00430-019-00632-7

An investigation of the utility of plasma Cytomegalovirus (CMV) microRNA detection to predict CMV DNAemia in allogeneic hematopoietic stem cell transplant recipients

Talaya A, Giménez E, Pascual MJ, Gago B, Piñana JL, Hernández-Boluda JC, Vázquez L, García M, Serrano D, Hernández M, Albert E, Solano C, Navarro D

2019

doi: 10.1111/tid.13158

Incidence, risk factors, and outcome of pulmonary invasive fungal disease after respiratory virus infection in allogeneic hematopoietic stem cell transplantation recipients

Piñana JL, Gómez MD, Montoro J, Lorenzo I, Pérez A, Giménez E, González-Barberá EM, Carretero C, Guerreiro M, Salavert M, Sanz G, Hernández-Boluda JC, Borrás R, Sanz J, Solano C, Navarro D