Development of pre-clinical models

  • To develop preclinical models reproducing accurately the different clinical types of leukemia and lymphoma as well as allogeneic transplantation, based on transformed cell lines, patient’s samples and murine models
  • To develop in vivo and in vitro assays for the analysis of novel targeted
  • To analyze microenvironment regulatory networks
  • To study molecular mechanisms of drug resistance.
  • To analyze the implications of molecular lesions in the leukemogenesis and chemorresistance through genomic edition using CRISPR-CAS9 technology and minigenes, among others.
  • To generate mutant mice to study the impact of alterations on leukemogenesis

Leading Researcher

Predoctoral

Predoctoral

Predoctoral