Artículos

doi: 10.1038/s41591-020-1008-z

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Bernard E, Nannya Y, Hasserjian RP, Devlin SM, Tuechler H, Medina-Martinez JS, Yoshizato T, Shiozawa Y, Saiki R, Malcovati L, Levine MF, Arango JE, Zhou Y, Solé F, Cargo CA, Haase D, Creignou M, Germing U, Zhang Y, Gundem G, Sarian A, van de Loosdrecht AA, Jädersten M, Tobiasson M, Kosmider O, Follo MY, Thol F, Pinheiro RF, Santini V, Kotsianidis I, Boultwood J, Santos FPS, Schanz J, Kasahara S, Ishikawa T, Tsurumi H, Takaori-Kondo A, Kiguchi T, Polprasert C, Bennett JM, Klimek VM, Savona MR, Belickova M, Ganster C, Palomo L, Sanz G, Ades L, Della Porta MG, Smith AG, Werner Y, Patel M, Viale A, Vanness K, Neuberg DS, Stevenson KE, Menghrajani K, Bolton KL, Fenaux P, Pellagatti A, Platzbecker U, Heuser M, Valent P, Chiba S, Miyazaki Y, Finelli C, Voso MT, Shih LY, Fontenay M, Jansen JH, Cervera J, Atsuta Y, Gattermann N, Ebert BL, Bejar R, Greenberg PL, Cazzola M, Hellström-Lindberg E, Ogawa S, Papaemmanuil E

doi: 10.1111/ejh.13417

Acute Myeloid Leukemia With inv(3)(q21.3q26.2)/t(3;3)(q21.3;q26.2): Study of 61 Patients Treated With Intensive Protocols

Sitges M, Boluda B, Garrido A, Morgades M, Granada I, Barragan E, Arnan M, Serrano J, Tormo M, Miguel Bergua J, Colorado M, Salamero O, Esteve J, Benavente C, Pérez-Encinas M, Coll R, Martí-Tutusaus JM, Brunet S, Sierra J, Ángel Sanz M, Montesinos P, Ribera JM, Vives S; PETHEMA, CETLAM cooperative groups.

doi: 10.1186/s13045-020-00923-0.

Post-transplant cyclophosphamide versus antithymocyte globulin in patients with acute myeloid leukemia in first complete remission undergoing allogeneic stem cell transplantation from 10/10 HLA-matched unrelated donors

Brissot E, Labopin M, Moiseev I, Cornelissen JJ, Meijer E, Van Gorkom G, Rovira M, Ciceri F, Griskevicius L, Blaise D, Forcade E, Mistrik M, Mielke S, Bulabois CE, Niittyvuopio R, Deconinck E, Ruggeri A, Sanz J, Spyridonidis A, Savani B, Giebel S, Nagler A, Mohty M.

doi: 10.1080/10428194.2020.1788015

Feasibility of thiotepa addition to the fludarabine-busulfan conditioning with tacrolimus/sirolimus as graft vs host disease prophylaxis

Fox ML, García-Cadenas I, Pérez AM, Villacampa G, Piñana JL, Ortí G, Montoro J, Roldán E, Bosch Vilaseca A, Martino R, Salamero O, Saavedra S, Hernandez-Boluda JC, Esquirol A, Sierra J, Sanz J, Solano C, Bosch F, Barba P, Valcarcel D.

doi: 10.1186/s13045-020-00929-8

Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy

doi: 10.1007/s00277-020-04186-0

Drug-drug interactions of newly approved small molecule inhibitors for acute myeloid leukemia

Megías-Vericat JE, Solana-Altabella A, Ballesta-López O, Martínez-Cuadrón D, Montesinos P.

doi: 10.1016/S0049-3848(20)30399-6

Advances in the management of coagulopathy in acute promyelocytic leukemia

Sanz MA, Montesinos P.

doi: 10.1038/s41409-020-01005-y

Measurable residual disease (MRD) testing for acute leukemia in EBMT transplant centers: a survey on behalf of the ALWP of the EBMT

Nagler A, Baron F, Labopin M, Polge E, Esteve J, Bazarbachi A, Brissot E, Bug G, Ciceri F, Giebel S, Gilleece MH, Gorin NC, Lanza F, Peric Z, Ruggeri A, Sanz J, Savani BN, Schmid C, Shouval R, Spyridonidis A, Versluis J, Mohty M.

doi: 10.3324/haematol.2019.223925

Obesity is a risk factor for acute promyelocytic leukemia: evidence from population and cross-sectional studies studies and correlation with flt3 mutations and polyunsaturated fatty acid metabolism.

Mazzarella L, Botteri E, Matthews A, Gatti E, Di Salvatore D, Bagnardi V, Breccia M, Montesinos P, Bernal T, Gil C, Ley TJ, Sanz M, Bhaskaran K, Lo Coco F, Pelicci PG

doi: 10.3324/haematol.2019.243410

Clinical Practice Recommendation on Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia Patients With FLT3-internal Tandem Duplication: A Position Statement From the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Bazarbachi A, Bug G, Baron F, Brissot E, Ciceri F, Dalle IA, Döhner H, Esteve J, Floisand Y, Giebel S, Gilleece M, Gorin NC, Jabbour E, Aljurf M, Kantarjian H, Kharfan-Dabaja M, Labopin M, Lanza F, Malard F, Peric Z, Prebet T, Ravandi F, Ruggeri A, Sanz J, Schmid C, Shouval R, Spyridonidis A, Versluis J, Vey N, Savani BN, Nagler A, Mohty M.

doi: 10.1038/s41409-020-0970-x

Management of Patients With Acute Leukemia During the COVID-19 Outbreak: Practical Guidelines From the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Brissot E, Labopin M, Baron F, Bazarbachi A, Bug G, Ciceri F, Esteve J, Giebel S, Gilleece MH, Gorin NC, Lanza F, Peric Z, Ruggeri A, Sanz J, Savani BN, Schmid C, Shouval R, Spyridonidis A, Versluis J, Nagler A, Mohty M.

doi: 10.1016/j.hemonc.2020.05.007

Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants

Mannan A, Muhsen IN, Barragán E, Sanz MA, Mohty M, Hashmi SK, Aljurf M.

doi: 10.5045/br.2020.2020059

Lineage Switch From B Lymphoblastic Leukemia With KMT2A-rearranged to Mixed-Phenotype Acute Leukemia Under Daratumumab

Marco-Ayala J, Vicente AI, Such E, Luna I, Andreu R, Sempere A, Romero S, Peris MLS.

doi: 10.1016/S2352-3026(20)30205-2

Special Considerations in the Management of Adult Patients With Acute Leukaemias and Myeloid Neoplasms in the COVID-19 Era: Recommendations From a Panel of International Experts

Zeidan AM, Boddu PC, Patnaik MM, Bewersdorf JP, Stahl M, Rampal RK, Shallis R, Steensma DP, Savona MR, Sekeres MA, Roboz GJ, DeAngelo DJ, Schuh AC, Padron E, Zeidner JF, Walter RB, Onida F, Fathi A, DeZern A, Hobbs G, Stein EM, Vyas P, Wei AH, Bowen DT, Montesinos P, Griffiths EA, Verma AK, Keyzner A, Bar-Natan M, Navada SC, Kremyanskaya M, Goldberg AD, Al-Kali A, Heaney ML, Nazha A, Salman H, Luger S, Pratz KW, Konig H, Komrokji R, Deininger M, Cirici BX, Bhatt VR, Silverman LR, Erba HP, Fenaux P, Platzbecker U, Santini V, Wang ES, Tallman MS, Stone RM, Mascarenhas J.

doi: 10.1038/s41409-020-0803-y

Redefining and Measuring Transplant Conditioning Intensity in Current Era: A Study in Acute Myeloid Leukemia Patients

Spyridonidis A, Labopin M, Savani BN, Niittyvuopio R, Blaise D, Craddock C, Socié G, Platzbecker U, Beelen D, Milpied N, Cornelissen JJ, Ganser A, Huynh A, Griskevicius L, Giebel S, Aljurf M, Brissot E, Malard F, Esteve J, Peric Z, Baron F, Ruggeri A, Schmid C, Gilleece M, Gorin NC, Lanza F, Shouval R, Versluis J, Bug G, Fløisand Y, Ciceri F, Sanz J, Bazarbachi A, Nagler A, Mohty M.

doi: 10.1038/s41409-020-0835-3

Correction: Redefining and Measuring Transplant Conditioning Intensity in Current Era: A Study in Acute Myeloid Leukemia Patients

Spyridonidis A, Labopin M, Savani BN, Niittyvuopio R, Blaise D, Craddock C, Socié G, Platzbecker U, Beelen D, Milpied N, Cornelissen JJ, Ganser A, Huynh A, Griskevicius L, Giebel S, Aljurf M, Brissot E, Malard F, Esteve J, Peric Z, Baron F, Ruggeri A, Schmid C, Gilleece M, Gorin NC, Lanza F, Shouval R, Versluis J, Bug G, Fløisand Y, Ciceri F, Sanz J, Bazarbachi A, Nagler A, Mohty M.

doi: 10.1038/s41375-020-0917-7

Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification-an approach to classification of patients with t-MDS

Kuendgen A, Nomdedeu M, Tuechler H, Garcia-Manero G, Komrokji RS, Sekeres MA, Della Porta MG, Cazzola M, DeZern AE, Roboz GJ, Steensma DP, Van de Loosdrecht AA, Schlenk RF, Grau J, Calvo X, Blum S, Pereira A, Valent P, Costa D, Giagounidis A, Xicoy B, Döhner H, Platzbecker U, Pedro C, Lübbert M, Oiartzabal I, Díez-Campelo M, Cedena MT, Machherndl-Spandl S, López-Pavía M, Baldus CD, Martinez-de-Sola M, Stauder R, Merchan B, List A, Ganster C, Schroeder T, Voso MT, Pfeilstöcker M, Sill H, Hildebrandt B, Esteve J, Nomdedeu B, Cobo F, Haas R, Sole F, Germing U, Greenberg PL, Haase D, Sanz G.

doi: 10.1016/j.medcli.2020.04.032

Current status of acute myeloid leukaemia in Spain: Results from a Delphi study on its epidemiology, disease management and unmet clinical needs

Montesinos P, Gil A, Sierra J.

doi: 10.1111/ajt.16147

Cytomegalovirus DNAemia and risk of mortality in allogeneic hematopoietic stem cell transplantation: Analysis from the Spanish Hematopoietic Transplantation and Cell Therapy Group

Carlos Solano Lourdes Vázquez Estela Giménez Rafael de la Cámara Eliseo Albert Montserrat Rovira Ildefonso Espigado Carmen M. Calvo Javier López‐Jiménez María Suárez‐Lledó Anabella Chinea Albert Esquirol Ariadna Pérez Aránzazu Bermúdez Raquel Saldaña Inmaculada Heras Ana J. González‐Huerta Tamara Torrado Guiomar Bautista Montserrat Batlle Santiago Jiménez Carlos Vallejo Pere Barba María Á. Cuesta José L. Piñana David Navarro

doi: 10.1038/s41409-020-0921-6

Uniform graft-versus-host disease prophylaxis with posttransplant cyclophosphamide, sirolimus, and mycophenolate mofetil following hematopoietic stem cell transplantation from haploidentical, matched sibling and unrelated donors

Juan Montoro, José Luis Piñana, Juan C. Hernández-Boluda, Rafael Hernani, Ignacio Lorenzo, Ariadna Pérez, Manuel Guerreiro, Aitana Balaguer-Rosello, Guillermo F. Sanz, Carlos Carretero, Eliseo Albert, David Navarro, Miguel A. Sanz, Carlos Solano & Jaime Sanz

doi: 10.1038/s41409-020-0943-0

Community acquired respiratory virus infections in adult patients undergoing umbilical cord blood transplantation

Juan Montoro, Jaime Sanz, Ignacio Lorenzo, Aitana Balaguer-Roselló, Miguel Salavert, María Dolores Gómez, Manuel Guerreiro, Eva M. González Barberá, Cristina Aguado, Luiza Tofán, Guillermo F. Sanz, Miguel A. Sanz & José Luis Piñana

doi: 10.1186/s13045-020-00882-6

Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia: a comparative study of the ALWP EBMT

Sanz J, Galimard JE, Labopin M, Afanasyev B, Angelucci E, Ciceri F, Blaise D, Cornelissen JJ, Meijer E, Diez-Martin JL, Koc Y, Rovira M, Castagna L, Savani B, Ruggeri A, Nagler A, Mohty M; Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT). Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia: a comparative study of the ALWP EBMT. J Hematol Oncol. 2020 May 6;13(1):46. doi: 10.1186/s13045-020-00882-6. PMID: 32375860; PMCID: PMC7201995.

doi: 10.1111/tid.13301

Assessment of Immunodeficiency Scoring Index Performance in Enterovirus/Rhinovirus Respiratory Infection After Allogeneic Hematopoietic Stem Cell Transplantation

Hernández-Boluda JC, Giménez E, Gómez MD, Balaguer-Roselló A, Gonzalez-Barberá E, Guerreiro M, Aguilar C, Navarro D, Solano C, Sanz J, Luis Piñana J.

doi: 10.1016/j.bbmt.2020.01.015

Features of Cytomegalovirus DNAemia Blips in Allogeneic Hematopoietic Stem Cell Transplant Recipients: Implications for Optimization of Preemptive Antiviral Therapy Strategies

Huntley D, Talaya A, Giménez E, Martínez A, Hernández-Boluda JC, Hernani R, Torres I, Alberola J, Albert E, Piñana JL, Solano C, Navarro D

doi: 10.1038/s41375-020-0849-2

Genomic characterization of patients with polycythemia vera developing resistance to hydroxyurea

Alvarez-Larrán A, Díaz-González A, Such E, Mora E, Andrade-Campos M, García-Hernández C, Gómez-Casares MT, García-Gutiérrez V, Carreño-Tarragona G, Garrote M, Fernández-Ibarrondo L, Cervera J, Bellosillo B, Cervantes F, Hernández-Boluda JC; MPN Spanish Group (GEMFIN).

doi: 10.3390/cancers12051313

PLZF-RAR α, NPM1-RAR α, and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review

Sobas M, Talarn-Forcadell MC, Martínez-Cuadrón D, Escoda L, García-Pérez MJ, Mariz J, Mela-Osorio MJ, Fernández I, Alonso-Domínguez JM, Cornago-Navascués J, Rodríguez-Macias G, Amutio ME, Rodríguez-Medina C, Esteve J, Sokół A, Murciano-Carrillo T, Calasanz MJ, Barrios M, Barragán E, Sanz MA, Montesinos P.

doi: 10.1038/s41409-020-0950-1

Peripheral Blood Regulatory T Cells and Occurrence of Cytomegalovirus DNAemia After Unmanipulated Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Posttransplant Cyclophosphamide

Huntley D, Giménez E, Pascual MJ, Vázquez L, Amat P, Remigia MJ, Hernández M, Hernández-Boluda JC, Gago B, Piñana JL, García M, Pérez A, Alberola J, Gozalbo-Rovira R, Albert E, Solano C, Navarro D

doi: 10.1038/s41598-020-61589-9

Analysis of SNP Array Abnormalities in Patients with DE NOVO Acute Myeloid Leukemia with Normal Karyotype

Ibáñez M, Such E, Onecha E, Gómez-Seguí I, Liquori A, Sellés J, Hervás-Marín D, Barragán E, Ayala R, LLop M, López-Pavía M, Rapado I, Neef A, Sanjuan-Pla A, Sargas C, Gonzalez-Romero E, Boluda-Navarro M, Andreu R, Senent L, Montesinos P, Martínez-López J, Angel Sanz M, Sanz G, Cervera J

doi: 10.1016/j.jgo.2020.03.019

Treatment of acute promyelocytic leukemia in older patients: recommendations of an International Society of Geriatric Oncology (SIOG) task force.

Klepin HD, Neuendorff NR, Larson RA, Hamaker ME, Breccia M, Montesinos P, Cordoba R.

doi: 10.1016/j.eimc.2019.01.013

Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Network for Research in Infectious Diseases (REIPI) and the Spanish Society of Haematology and Haemotherapy (SEHH) on the management of febrile neutropenia in patients with hematological malignancies.

Gudiol C, Aguilar-Guisado M, Azanza JR, Candel FJ, Cantón R, Carratalà J, Garcia-Vidal C, Jarque I, Lizasoain M, Gil-Bermejo JM, Ruiz-Camps I, Sánchez-Ortega I, Solano C, Suárez-Lledó M, Vázquez L, de la Cámara R

doi: 10.3390/cancers12040968.

Acute promyelocytic leukemia during pregnancy: A systematic review of the literature

Santolaria A, Perales A, Montesinos P, Sanz MA

doi: 10.1016/j.clml.2020.03.011

Treatment of Frail Older Adults and Elderly Patients With Philadelphia Chromosome-negative Acute Lymphoblastic Leukemia: Results of a Prospective Trial With Minimal Chemotherapy

Ribera, J.-M., García, O., Chapchap, E.C., (...) Montesinos, P., López, A., Serrano, J.

doi: 10.3390/ijms21082714.

MTHFR and VDR Polymorphisms Improve the Prognostic Value of MYCN Status on Overall Survival in Neuroblastoma Patients.

Olivera GG, Yáñez Y, Gargallo P, Sendra L, Aliño SF, Segura V, Sanz MÁ, Cañete A, Castel V, Font De Mora J, Hervás D, Berlanga P, Herrero MJ

doi: 10.1038/s41375-020-0815-

Determinants of survival in myelofibrosis patients undergoing allogeneic hematopoietic cell transplantation

Hernández-Boluda JC, Pereira A, Kröger N, Beelen D, Robin M, Bornhäuser M, Angelucci E, Vitek A, Blau IW, Niittyvuopio R, Finke J, Cornelissen JJ, Passweg J, Dreger P, Petersen E, Kanz L, Sanz J, Zuckerman T, Zinger N, Iacobelli S, Hayden P, Czerw T, McLornan D, Yakoub-Agha I

doi: 10.3324/haematol.2018.211904.

Daratumumab Displays in Vitro and in Vivo Anti-Tumor Activity in Models of B-cell non-Hodgkin Lymphoma and Improves Responses to Standard Chemo-Immunotherapy Regimens

Vidal-Crespo A, Matas-Céspedes A, Rodriguez V, Rossi C, Valero JG, Serrat N, Sanjuan-Pla A, Menéndez P, Roué G, López-Guillermo A, Giné E, Campo E, Colomer D, Bezombes C, van Bueren JL, Chiu C, Doshi P, Pérez-Galán P

doi: 10.1056/NEJMoa1917635

Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease

Zeiser R, von Bubnoff N, Butler J, Mohty M, Niederwieser D, Or R, Szer J, Wagner EM, Zuckerman T, Mahuzier B, Xu J, Wilke C, Gandhi KK, Socié G; REACH2 Trial Group. Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease.

doi: 10.3324/haematol.2019.240853

Are next-generation sequencing results knocking on Heaven’s door for transplantation planning in chronic myelomonocytic leukemia?

Sanz G., Ibañez M., Mora E.

doi: 10.3390/cancers12030624

Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single PML-RARA Fusion Gene

Alessandro Liquori ,Mariam Ibañez ,Claudia Sargas,Miguel Ángel Sanz,Eva Barragán and José Cervera.

doi: 10.1038/s41375-020-0773-5

Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study

Montesinos P, Roboz GJ, Bulabois CE, Subklewe M, Platzbecker U, Ofran Y, Papayannidis C, Wierzbowska A, Shin HJ, Doronin V, Deneberg S, Yeh SP, Ozcan MA, Knapper S, Cortes J, Pollyea DA, Ossenkoppele G, Giralt S, Döhner H, Heuser M, Xiu L, Singh I, Huang F, Larsen JS, Wei AH

doi: 10.1016/j.blre.2020.100675

Tyrosine kinase inhibitors for acute myeloid leukemia: A step toward disease control?

Megías-Vericat JE, Ballesta-López O, Barragán E, Martínez-Cuadrón D, Montesinos P

doi: 10.1038/s41375-020-0783-3

Management of hyperleukocytosis and impact of leukapheresis among patients with acute myeloid leukemia (AML) on short- and long-term clinical outcomes: a large, retrospective, multicenter, international study

Stahl M, Shallis RM, Wei W, Montesinos P, Lengline E, Neukirchen J, Bhatt VR, Sekeres MA, Fathi AT, Konig H, Luger S, Khan I, Roboz GJ, Cluzeau T, Martínez-Cuadron D, Raffoux E, Germing U, Umakanthan JM, Mukherjee S, Brunner AM, Miller A, McMahon CM, Ritchie EK, Rodríguez-Veiga R, Itzykson R, Boluda B, Rabian F, Tormo M, Acuña-Cruz E, Rabinovich E, Yoo B, Cano I, Podoltsev NA, Bewersdorf JP, Gore S, Zeidan AM

doi: 10.1007/s40261-019-00881-7

Practical Considerations for Treatment of Relapsed/Refractory FLT3-ITD Acute Myeloid Leukaemia with Quizartinib: Illustrative Case Reports

Martínez-Cuadrón D, Rodríguez-Macías G, Rodríguez-Veiga R, Boluda B, Montesinos P

doi: 10.1038/s41409-020-0865-x

Reconstitution of cytomegalovirus-specific T-cell immunity following unmanipulated haploidentical allogeneic hematopoietic stem cell transplantation with posttransplant cyclophosphamide

Huntley D, Giménez E, Pascual MJ, Remigia MJ, Amat P, Vázquez L, Hernández M, Hernández-Boluda JC, Gago B, Piñana JL, García M, Martínez A, Mateo E, Gozalbo-Rovira R, Albert E, Solano C, Navarro D

doi: 10.1200/JCO.19.01231

Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma

Paiva B, Puig N, Cedena MT, Rosiñol L, Cordón L, Vidriales MB, Burgos L, Flores-Montero J, Sanoja-Flores L, Lopez-Anglada L, Maldonado R, de la Cruz J, Gutierrez NC, Calasanz MJ, Martin-Ramos ML, Garcia-Sanz R, Martinez-Lopez J, Oriol A, Blanchard MJ, Rios R, Martin J, Martinez-Martinez R, Sureda A, Hernandez MT, de la Rubia J, Krsnik I, Moraleda JM, Palomera L, Bargay J, Van Dongen JJM, Orfao A, Mateos MV, Blade J, San-Miguel JF, Lahuerta JJ; GEM (Grupo Español de Mieloma)/PETHEMA (Programa Para el Estudio de la Terapéutica en Hemopatías Malignas) Cooperative Study Group. Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma)

doi: 10.1038/s41409-019-0698-7

The effect of timing on community acquired respiratory virus infection mortality during the first year after allogeneic hematopoietic stem cell transplantation: a prospective epidemiological survey.

Piñana JL, Pérez A, Montoro J, Hernani R, Lorenzo I, Giménez E, Gómez MD(6), Guerreiro M(4), González-Barberá EM(6), Carretero C,Salavert M, Balaguer-Roselló A(4), Sanz G, Hernández-Boluda JC,Solano C, Sanz J, Navarro D

doi: 10.1016/j.bbmt.2019.10.014

Prospective Randomized Study Comparing Myeloablative Unrelated Umbilical Cord Blood Transplantation versus HLA-Haploidentical Related Stem Cell Transplantation for Adults with Hematologic Malignancies

Sanz J, Montoro J, Solano C, Valcárcel D, Sampol A, Ferrá C, Parody R, Lorenzo I, Montesinos P, Ortí G, Hernández-Boluda JC, Balaguer-Roselló A, Guerreiro M, Carretero C, Sanz GF, Sanz MA, Piñana JL

doi: 10.1016/j.clml.2019.09.616

Outcome of a Real-Life Population of Patients With Acute Promyelocytic Leukemia Treated According to the PETHEMA Guidelines: The Polish Adult Leukemia Group (PALG) Experience.

Sobas M, Czyż A, Montesinos P, Armatys A, Helbig G, Hołowiecka A, Pluta A, Zarzycka E, Piątkowska-Jakubas B, Majcherek M, Lewandowski K, Gołos A, Paluszewska M, Podhorecka M, Oleksiuk J, Skręt A, Hawrylecka D, Guzicka-Kazimierczak RE, Wątek M, Gromek T, Charliński G, Grosicki S, Holojda J, Miśkiewicz W, Martinez-Cuadrón D, Sanz MA, Wróbel T, Wierzbowska A, Giebel S.

doi: 10.1002/cam4.2814

A pediatric regimen for adolescents and young adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: Results of the ALLRE08 PETHEMA trial

Ribera JM, Morgades M, Montesinos P, Tormo M, Martínez-Carballeira D, González-Campos J, Gil C, Barba P, García-Boyero R, Coll R, Pedreño M, Ribera J, Mercadal S, Vives S, Novo A, Genescà E, Hernández-Rivas JM, Bergua J, Amigo ML, Vall-Llovera F, Martínez-Sánchez P, Calbacho M, García-Cadenas I, Garcia-Guiñon A, Sánchez-Sánchez MJ, Cervera M, Feliu E, Orfao A; PETHEMA Group, Spanish Society of Hematolog

doi: 10.1038/s41375-020-0728-x

Impact of somatic mutations in myelodysplastic patients with isolated partial or total loss of chromosome 7

Crisà E, Kulasekararaj AG, Adema V, Such E, Schanz J, Haase D, Shirneshan K, Best S, Mian SA, Kizilors A, Cervera J, Lea N, Ferrero D, Germing U, Hildebrandt B, Martínez ABV, Santini V, Sanz GF, Solé F, Mufti GJ

doi: 10.1111/bjh.16432

Improving the prediction of acute myeloid leukaemia outcomes by complementing mutational profiling with ex vivo chemosensitivity

Onecha E, Ruiz-Heredia Y, Martínez-Cuadrón D, Barragán E, Martinez-Sanchez P, Linares M, Rapado I, Perez-Oteyza J, Magro E, Herrera P, Rojas JL, Gorrochategui J, Villoria J, Boluda B, Sargas C, Ballesteros J, Montesinos P, Martínez-López J, Ayala R

doi: 10.1080/10428194.2020.1728753

Patterns of care and clinical outcomes of patients with newly diagnosed acute myeloid leukemia presenting with hyperleukocytosis who do not receive intensive chemotherapy

Shallis RM, Stahl M, Wei W, Montesinos P, Lengline E, Neukirchen J, Bhatt VR, Sekeres MA, Fathi AT, Konig H, Luger S, Khan I, Roboz GJ, Cluzeau T, Martínez-Cuadron D, Raffoux E, Germing U, Umakanthan JM, Mukhereje S, Brunner AM, Miller A, McMahon CM, Ritchie EK, Rodríguez-Veiga R, Itzykson R, Boluda B, Rabian F, Tormo M, Acuña-Cruz E, Rabinovich E, Yoo B, Cano I, Podoltsev NA, Bewersdorf JP, Gore S, Zeidan AM.

doi: 10.1111/ejh.13370

Use of eltrombopag for patients 65 years old or older with immune thrombocytopenia

González-López TJ, Sánchez-González B, Jarque I, Bernat S, Fernández-Fuertes F, Caparrós I, Soto I, Fernández-Rodríguez A, Bolaños E, Pérez-Rus G, Pascual C, Hernández-Rivas JA, López-Ansoar E, Gómez-Nuñez M, Martínez-Robles V, Olivera P, Yera Cobo M, Peñarrubia MJ, Fernández-Miñano C, de Cabo E, Martínez Badas MP, Perdomo G, García-Frade LJ

doi: 10.1038/s41375-020-0758-4

Outcome of older (≥70 years) APL patients frontline treated with or without arsenic trioxide-an International Collaborative Study

Kayser S, Rahmé R, Martínez-Cuadrón D, Ghiaur G, Thomas X, Sobas M, Guerci-Bresler A, Garrido A, Pigneux A, Gil C, Raffoux E, Tormo M, Vey N, de la Serna J, Salamero O, Lengfelder E, Levis MJ, Fenaux P, Sanz MA, Platzbecker U, Schlenk RF, Adès L, Montesinos P

doi: 10.1111/tid.13206

Incidence, features and outcomes of Cytomegalovirus DNAemia in unmanipulated haploidentical allogeneic hematopoietic stem cell transplantation with post‐transplantation cyclophosphamide

Huntley D, Giménez E, Pascual MJ, Hernández-Boluda JC, Gago B, Vázquez L, Piñana JL, García M, Pérez A, Serrano D, Hernández M, Albert E, Solano C, Navarro D

doi: 10.1007/s11239-020-02065-z

Factor XIII deficiency in two Spanish families with a novel variant in gene F13A1 detected by next-generation sequencing; symptoms and clinical management

Andrés Moret, Ángel Zúñiga, Javier Marco Ayala, Alessandro Liquori, Ana Rosa Cid, Saturnino Haya, Fernando Ferrando, Amando Blanquer, José Cervera & Santiago Bonanad

doi: 10.1016/j.bbmt.2020.02.003

Potential Survival Benefit for Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation After Nivolumab Therapy for Relapse/Refractory Hodgkin Lymphoma: Real-Life Experience in Spain

Martínez C, Carpio C, Heras I, Ríos-Herranz E, Buch J, Gutierrez A, Romero S, Zeberio I, García-García I, Rodriguez-Izquierdo A, Alonso R, Bargay J, Barrenetxea C, Domingo-Doménech E, de Haro ME, Palomera L, García-Sanz R; Spanish Group of Lymphoma and Bone Marrow Transplantation (GELTAMO).

doi: 10.1038/s41409-019-0525-1

Daratumumab Is a Safe and Effective Rescue Therapy for Multiple Myeloma Patients Who Relapse After allo-HSCT

Gonzalez-Rodriguez AP, Lopez-Corral L, Fajardo DFM, Gonzalez-Huerta AJ, Palomo P, Bermudez A, Ripa TZ, Santos-Diaz P, Gonzalez-Muñiz S, Zanabilli J, Ubieto AJ, de Arriba F, Arnao-Herraiz M, Sordo-Bahamonde C, López-Soto A, Gonzalez S, Rosiñol L, Mateos MV.

doi: 10.1016/j.bbmt.2019.08.020

Partial T Cell-Depleted Peripheral Blood Stem Cell Transplantation from HLA-Identical Sibling Donors for Patients with Severe Aplastic Anemia.

Sanz J, Moscardó F, Montoro J, Cano I, Guerreiro M, Dasí MA, Solves P, Lorenzo I, Gómez-Segui I, Montesinos P, Mora E, Arnao M, Sempere A, Jarque I, Carretero C, Senent L, Vicente A, Andreu R, Luna I, Balaguer-Roselló A, Carpio N, Sanz GF, Sanz MA, Piñana JL.

doi: 10.1038/s41375-019-0534-5

Prognostic factors for adult single cord blood transplantation among European and Japanese populations: the Eurocord/ALWP-EBMT and JSHCT/JDCHCT collaborative study.

Kanda J, Hayashi H, Ruggeri A, Kimura F, Volt F, Takahashi S, Labopin M, Kako S, Tozatto-Maio K, Yano S, Sanz G, Uchida N, Van Lint MT, Kato S, Mohty M, Forcade E, Kanamori H, Sierra J, Ohno Y, Saccardi R, Fukuda T, Ichinohe T, Takanashi M, Rocha V, Okamoto S, Nagler A, Atsuta Y, Gluckman E.

doi: 10.1016/j.jinf.2019.12.022

The clinical benefit of instituting a prospective clinical community-acquired respiratory virus surveillance program in allogeneic hematopoietic stem cell transplantation

Piñana J, Montoro J, Aznar C, Lorenzo I, Gómez M, Guerreiro M, Carretero C, González-Barberá E, Balaguer-Roselló A, Sanz R, Salavert M, Navarro D, Sanz M, Sanz G, Sanz J

doi: 10.1182/blood.2019002697

Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia

Döhner K, Thiede C, Jahn N, Panina E, Gambietz A, Larson RA, Prior TW, Marcucci G, Jones D, Krauter J, Heuser M, Voso MT, Ottone T, Nomdedeu JF, Mandrekar SJ, Klisovic RB, Wei AH, Sierra J, Sanz MA, Brandwein JM, de Witte T, Jansen JH, Niederwieser D, Appelbaum FR, Medeiros BC, Tallman MS, Schlenk RF, Ganser A, Serve H, Ehninger G, Amadori S, Gathmann I, Benner A, Pallaud C, Stone RM, Döhner H, Bloomfield CD

doi: 10.1007/s00277-019-03820-w

Correction to: Update on management and progress of novel therapeutics for R/R AML: an Iberian expert panel consensus (Annals of Hematology, (2019), 98, 11, (2467-2483), 10.1007/s00277-019-03820-w)

Pau Montesinos,Juan BerguaJoana Infante,Jordi Esteve,José Eduardo Guimaraes,Jordi Sierra,Miguel Ángel Sanz

doi: 10.1128/AAC.01415-19

High Heterogeneity of Multidrug-Resistant Enterobacteriaceae Fecal Levels in Hospitalized Patients Is Partially Driven by Intravenous β-Lactams

Djukovic A, González-Barberá EM, Sanz J, Artacho A, Peñaranda I, Herrera B, Garzón MJ, Salavert M, López-Hontangas JL, Xavier KB, Kuster B, Debrauwer L, Rolain JM, Sanz MA, Xavier JB, Ubeda C

doi: 10.1016/j.medcli.2019.11.007

Clinico-biological characteristics of patients with myelofibrosis: an analysis of 1,000 cases from the Spanish Registry of Myelofibrosis.

Pastor-Galán I, Hernández-Boluda JC, Correa JG, Alvarez-Larrán A, Ferrer-Marín F, Raya JM, Ayala R, Velez P, Pérez-Encinas M, Estrada N, García-Gutiérrez V, Fox ML, Payer A, Kerguelen A, Cuevas B, Durán MA, Ramírez MJ, Gómez-Casares MT, Mata-Vázquez MI, Mora E, Martínez-Valverde C, Arbelo E, Angona A, Magro E, Antelo ML, Somolinos N, Cervantes F; en representación del Grupo Español de Enfermedades Mieloproliferativas Filadelfia Negativas (GEMFIN)

doi: 10.1016/j.jinf.2020.01.001

Clinical significance of Pneumocystis jirovecii DNA detection by real-time PCR in hematological patient respiratory specimens

Piñana, J. L., Albert, E., Gómez, M. D., Pérez, A., Hernández-Boluda, J. C., Montoro, J., Salavert, M., González, E. M., Tormo, M., Giménez, E., Villalba, M., Balaguer-Roselló, A., Hernani, R., Bueno, F., Borrás, R., Sanz, J., Solano, C., & Navarro, D.

doi: 10.1007/s00430-019-00632-7

An investigation of the utility of plasma Cytomegalovirus (CMV) microRNA detection to predict CMV DNAemia in allogeneic hematopoietic stem cell transplant recipients

Talaya A, Giménez E, Pascual MJ, Gago B, Piñana JL, Hernández-Boluda JC, Vázquez L, García M, Serrano D, Hernández M, Albert E, Solano C, Navarro D

doi: 10.1182/hematology.2019000042

In MDS, is higher risk higher reward?

Sanz GF

doi: 10.1111/tid.13158

Incidence, risk factors, and outcome of pulmonary invasive fungal disease after respiratory virus infection in allogeneic hematopoietic stem cell transplantation recipients

Piñana JL, Gómez MD, Montoro J, Lorenzo I, Pérez A, Giménez E, González-Barberá EM, Carretero C, Guerreiro M, Salavert M, Sanz G, Hernández-Boluda JC, Borrás R, Sanz J, Solano C, Navarro D

doi: 10.3390/ijms20246106

The Q-LAMP Method Represents a Valid and Rapid Alternative for the Detection of the BCR-ABL1 Rearrangement in Philadelphia-Positive Leukemias.

Stella S, Gottardi EM, Favout V, Barragan Gonzalez E, Errichiello S, Vitale SR, Fava C, Luciano L, Stagno F, Grimaldi F, Pironi L, Sargas Simarro C, Vigneri P, Izzo B.

doi: 10.1016/j.bbmt.2019.07.031

Myeloablative Unrelated Cord Blood Transplantation in Adolescents and Young Adults with Acute Leukemia.

Hayashi H, Volt F, Sanz J, Petersen E, Dhedin N, Hough R, Milpied N, Angelucci E, Yakoub-Agha I, Michallet M, Michel G, Aljurf M, Kenzey C, Rocha V, Dalle JH, Bader P, Ruggeri A, Gluckman E; Eurocord, Cellular Therapy & Immunobiology Working Party, and Paediatric Diseases Working Party of the European Society for Blood and Marrow Transplantation

doi: 10.1182/blood-2019-122620

Emerging Mutations at Relapse in Patients with FLT3-Mutated Relapsed/Refractory Acute Myeloid Leukemia Who Received Gilteritinib Therapy in the Phase 3 Admiral Trial.

Catherine C. Smith, Mark J. Levis, Alexander E. Perl, Giovanni Martinelli, Andreas Neubauer, Ellin Berman, Pau Montesinos, Maria R. Baer, Richard A. Larson, Wen Chien Chou, Hisayuki Yokoyama, Christian Recher, Sung Soo Yoon, Jason E. Hill, Matt Rosales, Erkut Bahceci

doi: 10.1038/s41409-019-0731-x

Ruxolitinib in refractory acute and chronic graft-versus-host disease: a multicenter survey study

Escamilla Gómez V, García-Gutiérrez V, López Corral L, García Cadenas I, Pérez Martínez A, Márquez Malaver FJ, Caballero-Velázquez T, González Sierra PA, Viguria Alegría MC, Parra Salinas IM, Calderón Cabrera C, González Vicent M, Rodríguez Torres N, Parody Porras R, Ferra Coll C, Orti G, Valcárcel Ferreiras D, De la Cámara LLanzá R, Molés P, Velázquez-Kennedy K, João Mende M, Caballero Barrigón D, Pérez E, Martino Bofarull R, Saavedra Gerosa S, Sierra J, Poch M, Zudaire Ripa MT, Díaz Pérez MA, Molina Angulo B, Sánchez Ortega I, Sanz Caballer J, Montoro Gómez J, Espigado Tocino I, Pérez-Simón JA

doi: 10.1182/bloodadvances.2019000680

Do next-generation sequencing results drive diagnostic and therapeutic decisions in MDS?

Sanz GF, Ibañez M, Such E.

doi: 10.1002/gcc.22788

Molecular profiling refines minimal residual disease-based prognostic assessment in adults with Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia.

Ribera J, Zamora L, Morgades M, Vives S, Granada I, Montesinos P, Gómez-Seguí I, Mercadal S, Guàrdia R, Nomdedeu J, Pratcorona M, Tormo M, Martínez-Lopez J, Hernández-Rivas JM, Ciudad J, Orfao A, González-Campos J, Barba P, Escoda L, Esteve J, Genescà E, Solé F, Feliu E, Ribera JM;

doi: 10.1111/ejh.13346

Characteristics and outcome of adult patients with acute promyelocytic leukemia and increased body mass index treated with the PETHEMA Protocols

Sobas M, Rodriguez-Veiga R, Vellenga E, Paluszewska M, De la Serna J, García-Álvarez F, Gil C, Brunet S, Bergua J, González-Campos J, Ribera JM, Tormo M, González M, Fernández I, Benavente C, González-Sanmiguel JD, Esteve J, Pérez-Encinas M, Salamero O, Manso F, Lowenberg B, Sanz MA, Montesinos P

doi: 10.1007/s00277-019-03820-w

Update on management and progress of novel therapeutics for R/R AML: an Iberian expert panel consensus

Montesinos P, Bergua J, Infante J, Esteve J, Guimaraes JE, Sierra J, Sanz MÁ.

doi: 10.1038/s41598-019-53209-y

Deciphering predictive factors for choice of thrombopoietin receptor agonist, treatment free responses, and thrombotic events in immune thrombocytopenia.

Lozano ML, Mingot-Castellano ME, Perera MM, Jarque I, Campos-Alvarez RM, González-López TJ, Carreño-Tarragona G, Bermejo N, Lopez-Fernandez MF, de Andrés A, Valcarcel D, Casado-Montero LF, Alvarez-Roman MT, Orts MI, Novelli S, Revilla N, González-Porras JR, Bolaños E, Rodríguez-López MA, Orna-Montero E, Vicente V.

doi: 10.1182/blood-2019-123310

The Disease-Risk Stratification Scheme (DRSS), a Contemporary Risk-Stratification System for Allogeneic Stem Cell Transplantation

Roni Shouval , Joshua A Fein, MD , Myriam Labopin, MD , Ali Bazarbachi, MD PhD , Frédéric Baron, MD PhD , Gesine Bug , Fabio Ciceri, MD , Selim Corbacioglu, MD , Sebastian Giebel, MD PhD , Maria H Gilleece, MD FRCPath, MB, BSc, FRCP , Silvia Montoto, MD , Zinaida Peric, MD PhD , Emmanuelle Polge, M.Sc , Annalisa Ruggeri, MD , Jaime Sanz, MDPhD , Bipin N. Savani, MD , Christoph Schmid, MD , Alexandros Spyridonidis, MD PhD , Jurjen Versluis, MD PhD , Ibrahim Yakoub-Agha, MD PhD , Mohamad Mohty, MD PhD , Arnon Nagler, MD MSc

doi: 10.3324/haematol.2018.204891

High prognostic value of measurable residual disease detection by flow cytometry in chronic lymphocytic leukemia patients treated with front-line fludarabine, cyclophosphamide, and rituximab, followed by three years of rituximab maintenance

García-Marco JA, Jiménez JL, Recasens V, Zarzoso MF, González-Barca E, De Marcos NS, Ramírez MJ, Parraga FJP, Yañez L, De La Serna Torroba J, Malo MDG, Ariznavarreta GD, Persona EP, Guinaldo MAR, De Paz Arias R, Llanos EB, Jarque I, Valle MDCF, Tatay AC, De Oteyza JP, Martin EMD, Fernández IP, Martinez RM, Costa MAA, Champ D, Suarez JG, Díaz MG, Ferrer S, Carbonell F, García-Vela JA; GELLC Study Group

doi: 10.2147/CEOR.S222879

Cost-Effectiveness Of Midostaurin In The Treatment Of Acute Myeloid Leukemia With The FLT3 Mutation In Spain

Ainhoa Arenaza, Raúl Diez, Jordi Esteve, Roberta Di Nicolantonio, Joana Gostkorzewicz, Carlos Martínez, Diana Martínez Llinàs, Joaquin Martinez-Lopez, Pau Montesinos, Aída Moure-Fernández, Jorge Sierra, and Joan Lluís Vinent

doi: 10.1016/j.eimc.2019.02.007

Reasons for noncompliance with the national guidelines for initial antiretroviral therapy of HIV-infected patients in Spain, 2010-2015

Gonzalez, J, Jarrin, I, del Amo, J, Navarro, ML, Gonzalez, MI, Blanco, JL, Sobrino, P, Hernando, V, Alejos, B, Alvarez, D, Jarrin, I, Sanz, N, Moreno, C, Munoz-Fernandez, MA, Garcia-Merino, I, Rico, CG, de la Fuente, JG, Torre, AG, Portilla, J, Merino, E, Reus, S, Boix, V, Giner, L, Gadea, C, Portilla, I, Pampliega, M, Diez, M, Rodriguez, JC, Sanchez-Paya, J, Gomez, JL, Hernandez, J, Aleman, MR, Alonso, MD, Hernandez, MI, Diaz-Flores, F, Garcia, D, Pelazas, R, Lirola, AL, Asensi, V, Valle, E, Carton, JA, Carmenado, MER, Rubio, R, Pulido, F, Bisbal, O, Hernando, A, Lagarde, M, Matarranz, M, Dominguez, L, Bermejo, L, Santacreu, M, Iribarren, JA, Arrizabalaga, J, Aramburu, MJ, Camino, X, Rodriguez-Arrondo, F, von Wichmann, MA, Tome, LP, Goenaga, MA, Bustinduy, MJ, Galparsoro, HA, Ibarguren, M, Umerez, M, Gutierrez, F, Masia, M, Padilla, S, Navarro, A, Montolio, F, Robledano, C, Colome, JG, Adsuar, A, Pascual, R, Fernandez, M, Garcia, E, Garcia, JA, Barber, X, Muga, R, Tor, J, Sanvisens, A, Berenguer, J, de Quiros, JCLB, Miralles, P, Gutierrez, I, Ramirez, M, Padilla, B, Gijon, P, Carrero, A, Aldamiz-Echevarria, T, Tejerina, F, Parras, FJ, Balsalobre, P, Diez, C, Vidal, F, Peraire, J, Vilades, C, Veloso, S, Vargas, M, Lopez-Dupla, M, Olona, M, Rull, A, Rodriguez-Gallego, E, Alba, V, Alonso, MM, Aldeguer, JL, Julia, MB, Pitarch, MT, Hernandez, IC, Munoz, EC, Tovar, SC, Lleti, MS, Navarro, JF, Gonzalez-Garcia, J, Arnalich, F, Arribas, JR, Bernardino, JI, Castro, JM, Escosa, L, Herranz, P, Hontanon, V, Garcia-Bujalance, S, Lopez-Hortelano, MG, Gonzalez-Baeza, A, Martin-Carbonero, ML, Mayoral, M, Mellado, MJ, Mican, R, Montejano, R, Montes, ML, Moreno, V, Perez-Valero, I, Rodes, B, Sainz, T, Sendagorta, E, Stella, NC, Valencia, E, Blanco, JR, Oteo, JA, Lbarra, V, Metola, L, Sanz, M, Perez-Martinez, L, Pascual, A, Ramos, C, Arazo, P, Gil, D, Dalmau, D, Jaen, A, Sanmarti, M, Cairo, M, Martinez-Lacasa, J, Velli, P, Font, R, Xercavins, M, Alonso, N, Rivero, M, Reparaz, J, de Alda, MGR, Irigoyen, C, Arraiza, MJ, Segura, F, Amengual, MJ, Navarro, G, Sala, M, Cervantes, M, Pineda, V, Segura, V, Navarro, M, Anton, E, Nogueras, MM, de los Santos, I, Sanz, JS, Aparicio, AS, Cepeda, CS, Fraile, LGF, Moreno, S, Casado, JL, Dronda, F, Moreno, A, Elias, MJP, Ayerbe, CG, Gutierrez, C, Madrid, N, Terron, SD, Marti, P, Ansa, U, Serrano, S, Vivancos, MJ, Cano, A, Bernal, E, Munoz, A, Garcia, F, Hernandez, J, Pena, A, Munoz, L, Perez, AB, Alvarez, M, Chueca, N, Vinuesa, D, Fernandez, JA, Del Romero, J, Rodriguez, C, Puerta, T, Carrio, JC, Vera, M, Ballesteros, J, Antela, A, Losada, E, Riera, M, Penaranda, M, Leyes, M, Ribas, MA, Campins, AA, Vidal, C, Fanjul, F, Murillas, J, Homar, F, Santos, J, Marquez, M, Viciana, I, Palacios, R, Perez I, Gonzalez CM, Viciana P, Espinosa N, Lopez-Cortes LF, Podzamczer D, Ferrer E, Imaz A, Tiraboschi J, Silva A, Saumoy M, Ribera E, Olalla J, del Arco A, de la Torre J, Prada JL, Guerrero JMGD, Martinez OJ, Vera FJ, Martinez L, Garcia J, Alcaraz B, Jimeno A, Poveda E, Pernas B, Mena A, Grandal M, Castro A, Pedreira JD, Munoz J, Zubero MZ, Baraia-Etxaburu JM, Ibarra S, Ferrero O, de Munain JL, Camara MM, Lopez I, de la Pena M, Galera, , Albendin H, Perez A, Iborra A, Moreno A, Campillo MA, Vidal A, Amador C, Pasquau F, Ena J, Benito C, Fenoll V, Suarez-Garcia I, Malmierca E, Gonzalez-Ruano P, Rodrigo DM, Mohamed-Balghata MO, Vidal MAG, de Zarraga MA, Perez VE, Molina MJT, Garcia JV, Carrera EPC, Gorgolas M, Cabello A, Alvarez B, Prieto L, Moreno JS, Caso AA, Prieto JD, Garcia EC, Puerto MJG, Vilalta RF, Ribera AF, Cohort Spanish HIV Res Network Co, Gonzalez J, Jarrin I, del Amo J, Navarro ML, Gonzalez MI, Blanco JL, Sobrino P, Hernando V, Alejos B, Alvarez D, Jarrin, , Sanz N, Moreno C, Munoz-Fernandez MA, Garcia-Merino I, Rico CG, de la Fuente JG, Torre AG, Portilla J, Merino E, Reus S, Boix V, Giner L, Gadea C, Portilla I, Pampliega M, Diez M, Rodriguez JC, Sanchez-Paya J, Gomez JL, Hernandez J, Aleman MR, Alonso MD, Hernandez MI, Diaz-Flores F, Garcia D, Pelazas R, Lirola AL, Asensi V, Valle E, Carton JA, Carmenado MER, Rubio R, Pulido F, Bisbal O, Hernando A, Lagarde M, Matarranz M, Dominguez L, Bermejo L, Santacreu M, Iribarren JA, Arrizabalaga J, Aramburu MJ, Camino X, Rodriguez-Arrondo F, von Wichmann MA, Tome LP, Goenaga MA, Bustinduy MJ, Galparsoro HA, Ibarguren M, Umerez M, Gutierrez F, Masia M, Padilla S, Navarro A, Montolio F, Robledano C, Colome JG, Adsuar A, Pascual R, Fernandez M, Garcia E, Garcia JA, Barber X, Muga R, Tor J, Sanvisens A, de Quiros JCLB, Miralles P, Gutierrez I, Padilla B, Gijon P, Carrero A, Aldamiz-Echevarria T, Tejerina F, Parras FJ, Balsalobre P, Diez C, Vidal F, Peraire J, Vilades C, Veloso S, Varga M, Lopez-Dupla M, Olona M, Rull A, Rodriguez-Gallego E, Alba V, Julia MB, Hernandez IC, Tovar SC, Navarro JF, Gonzalez-Garcia J, Arnalich F, Arribes JR, Bernardino I, Castro JM, Escosa L, Herranz P, Hontanon V, Garcia-Bujalance S, Lopez-Hortelano MG, Gonzalez-Baeza A, Martin-Carbonero ML, Mayoral M, Mellado MJ, Mican R, Montejano R, Montes ML, Moreno V, Perez-Valero I, Rodes B, Sainz T, Sendagorta E, Stella NC, Valencia E, Blanco JR, Oteo JA, Lbarra V, Metola L, Perez-Martinez L, Pascual A, Ramos C, Arazo P, Gil D, Dalmau D, Jaen A, Sanmarti M, Cairo M, Martinez-Lacasa J, Velli P, Font R, Xercavins M, Rivero M, Reparaz J, de Alda MGR, Irigoyen C, Arraiza MJ, Segura F, Amengual MJ, Navarro G, Sala M, Cervantes M, Pineda V, Navarro M, Anton E, Nogueras MM, de los Santos I, Sanz JS, Aparicio AS, Cepeda CS, Fraile LGF, Moreno S, Casado JL, Dronda F, Moreno A, Elias MJP, Ayerbe CG, Gutierrez C, Madrid N, Terron SD, Ansa U, Serrano S, Vivancos MJ, Bernal E, Garcia F, Hernandez J, Pena A, Munoz L, Perez AB, Alvarez M, Chueca N, Vinuesa D, Fernandez JA, Del Romero J, Rodriguez C, Puerta T, Carrio JC, Ballesteros J, Antela A, Losada E, Riera M, Penaranda M, Leyes M, Ribas MA, Campins AA, Vidal C, Fanjul F, Murillas J, Homar F, Santos J, Marquez M, Viciana I, Palacios R, Perez I, Gonzalez CM, Viciana P, Espinosa N, Lopez-Cortes LF, Podzamczer D, Ferrer E, Imaz A, Tiraboschi J, Silva A, Saumoy M, Ribera E, Olalla J, del Arco A, de la Torre J, Prada JL, Guerrero JMGD, Martinez OJ, Vera FJ, Martinez L, Garcia J, Alcaraz B, Jimeno A, Poveda E, Pernas B, Mena A, Grandal M, Castro A, Pedreira JD, Munoz J, Zubero MZ, Baraia-Etxaburu JM, Ibarra S, Ferrero O, de Munain JL, Camara MM, Lopez I, de la Pena M, Galera C, Albendin H, Iborra A, Moreno A, Campillo MA, Vidal A, Amador C, Pasquau F, Ena J, Benito C, Fenoll V, Suarez-Garcia I, Malmierca E, Gonzalez-Ruano P, Rodrigo DM, Mohamed-Balghata MO, Vidal MAG, de Zarraga MA, Perez VE, Molina MJT, Garcia JV, Carrera EPC, Gorgolas M, Cabello A, Alvarez B, Prieto L, Moreno JS, Caso AA, Prieto JD, Garcia EC, Puerto MJG, Vilalta RF, Ribera AF, Cohort Spanish HIV Res Network Co, Berenguer J, Ramirez M, Alonso MM, Aldeguer JL, Pitarch MT, Munoz EC, Lleti MS, Sanz M, Alonso N, Segura V, Marti P, Cano A, Munoz A, Vera M, Perez A

doi: 10.1111/bjh.16175

Spanish Guidelines for the use of targeted deep sequencing in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

Palomo L, Ibáñez M, Abáigar M, Vázquez I, Álvarez S, Cabezón M, Tazón-Vega B, Rapado I, Fuster-Tormo F, Cervera J, Benito R, Larrayoz MJ, Cigudosa JC, Zamora L, Valcárcel D, Cedena MT, Acha P, Hernández-Sánchez JM, Fernández-Mercado M, Sanz G, Hernández-Rivas JM, Calasanz MJ, Solé F, Such E

doi: 10.1016/j.transci.2019.09.011

Transfusion management in multiple myeloma patients receiving daratumumab: Experience of a single tertiary care centre.

Solves P, Tur S, Arnao M, Freiria C, Dominguez L, Pons MJ, Gómez I, Sanz GF, Carpio N

doi: 10.1186/s13756-019-0630-3

Genomic characterization of Citrobacter freundii strains coproducing OXA-48 and VIM-1 carbapenemase enzymes isolated in leukemic patient in Spain

Lalaoui R, Djukovic A, Bakour S, Hadjadj L, Sanz J, Salavert M, López-Hontangas JL, Sanz MA, Ubeda C, Rolain JM

doi: 10.1182/blood.2019000241

Bortezomib, lenalidomide, and dexamethasone as induction therapy prior to autologous transplantation in multiple myeloma.

osiñol L, Oriol A, Rios R, Sureda A, Blanchard MJ, Hernández MT, Martínez-Martínez R, Moraleda JM, Jarque I, Bargay J, Gironella M, de Arriba F, Palomera L, González-Montes Y, Martí JM, Krsnik I, Arguiñano JM, González ME, González AP, Casado LF, López-Anglada L, Paiva B, Mateos MV, San Miguel JF, Lahuerta JJ, Bladé J.

doi: 10.1056/NEJMoa1902688

Gilteritinib or chemotherapy for relapsed or refractory FLT3-mutated AML

Perl AE, Martinelli G, Cortes JE, Neubauer A, Berman E, Paolini S, Montesinos P, Baer MR, Larson RA, Ustun C, Fabbiano F, Erba HP, Di Stasi A, Stuart R, Olin R, Kasner M, Ciceri F, Chou WC, Podoltsev N, Recher C, Yokoyama H, Hosono N, Yoon SS, Lee JH, Pardee T, Fathi AT, Liu C, Hasabou N, Liu X, Bahceci E, Levis MJ

doi: 10.1001/jamaoncol.2019.3541

Haploidentical Stem Cell Transplantation With Posttransplant Cyclophosphamide Therapy vs Other Donor Transplantations in Adults With Hematologic Cancers: A Systematic Review and Meta-analysis

Gagelmann N, Bacigalupo A, Rambaldi A, Hoelzer D, Halter J, Sanz J, Bonifazi F, Meijer E, Itälä-Remes M, Marková M, Solano C, Kröger N

doi: 10.1016/j.clml.2019.09.254

Clinical Characteristics and Transfusion Management of Patients Diagnosed of Multiple Myeloma Receiving Daratumumab: Experience of a Single Centre

Mario Arnao, Pilar Solves, Albert Blanco, Lara Dominguez, Ines Gómez, Rafa Andreu, Samuel Romero, Isidro Jarque, Nelly Carpio, Guillermo Sanz

doi: https://doi.org/10.1016/S0145-2126(19)30200-0

Current treatment of acute promyelocytic leukemia

Sanz MA

doi: 10.1093/annonc/mdz374.003

Quizartinib in FLT3-ITD-Mutated Relapsed/Refractory Acute Myeloid Leukemia: QuANTUM-R Trial Results

Cortes JE, Khaled S, Martinelli G, Perl AE, Ganguly S, Russell NH, Kramer A, Dombret H, Hogge D, Jonas BA, Leung AY, Mehta P, Montesinos P, Radsak MP, Sica S, Arunachalam M, Holmes M, Namuyinga R, Zhang YF, Levis MJ, Cortes JE, Khaled S, Martinelli G, Perl AE, Ganguly S, Russell NH, Kramer A, Dombret H, Hogge D, Jonas BA, Leung AY, Mehta P, Radsak MP, Sica S, Arunachalam M, Holmes M, Namuyinga R, Zhang YF, Levis MJ, Montesinos P

doi: 10.1016/j.clml.2019.09.473

Intravenous Busulfan-Melphalan vs Melphalan as Preparative Regimen for Newly Diagnosed Multiple Myeloma: Long-Term Follow-Up of a Case-Control Study

Blanes M, Lorenzo JI, Ribas P, Jimenez A, Gonzalez JD, Cejalvo MJ, Solano C, Alegre A, de la Rubia J, Ribas P, Jimenez A, Gonzalez JD, Cejalvo MJ, Alegre A, Blanes M, Lorenzo JI, Solano C, de la Rubia J

doi: 10.1016/j.clml.2019.09.581

Single-Cell Characterization of Multiple Myeloma (MM) Immune Microenvironment Identifies CD27-negative T cells as Potential Tumor-Reactive Lymphocytes

Botta, C, Ruiz, CP, Goicoechea, I, Puig, N, Cedena, MT, Cordon, L, Zabaleta, A, Burgos, L, Maia, C, Rodriguez, S, Alignani, D, Rodriguez I, Sarvide S, Vilas-Zornoza A, Lorenzo-Vivas E, Rosinol L, Oriol A, Blanchard MJ, Tamayo RR, Balari AS, Martinez R, Martin J, Bargay J, De la Rubia J, Rossi M, Tagliaferri P, Tassone P, Gentile M, Merino J, Prosper F, Orfao A, Mateos MV, Lahuerta JJ, Blade J, San-Miguel J, Paiva B, Botta C, Ruiz CP, Goicoechea I, Puig N, Cedena MT, Zabaleta A, Burgos L, Maia C, Rodriguez S, Alignani D, Rodriguez I, Sarvide S, Vilas-Zornoza A, Lorenzo-Vivas E, Rosinol L, Oriol A, Blanchard MJ, Tamayo RR, Balari AS, Martinez R, Martin J, Bargay J, Rossi M, Tagliaferri P, Tassone P, Gentile M, Merino J, Prosper F, Orfao A, Mateos MV, Lahuerta JJ, Blade J, San-Miguel J, Paiva B, Cordon L, De la Rubia J

doi: 10.1016/j.clml.2019.09.581

Allogeneic hematopoietic stem cell transplantation in patients with multiple myeloma. Impact of disease characteristics, disease status at transplant, and prior number of lines of therapy. Results of retrospective, multicentre Spanish study

De la Rubia J, Perez A, Rosinol L, Arnao M, Teruel AI, Herrera I, Albo C, Vaz C, Krisnk I, Bermudez A, Pascual MJ, Encinas C, Cabanas V, Jurado M, Gonzalez S, Viguria MC, Chinea A, Ferra C, Sampol A, Solano C, Gonzalez MS, Rosinol L, Teruel AI, Herrera I, Albo C, Vaz C, Krisnk I, Bermudez A, Pascual MJ, Encinas C, Cabanas V, Jurado M, Gonzalez S, Viguria MC, Chinea A, Ferra C, Sampol A, De la Rubia J, Perez A, Arnao M, Solano C, Gonzalez MS

doi: doi: 10.1016/j.jiac.2019.03.007

Detection of plasmid-mediated colistin resistance, mcr-1 gene, in Escherichia coli isolated from high-risk patients with acute leukemia in Spain.

Lalaoui R, Djukovic A, Bakour S, Sanz J, Gonzalez-Barbera EM, Salavert M, López-Hontangas JL, Sanz MA, Xavier KB, Kuster B, Debrauwer L, Ubeda C, Rolain JM

doi: 10.1016/j.bbmt.2019.05.024

Noninfectious Neurologic Complications after Allogeneic Hematopoietic Stem Cell Transplantation.

Balaguer-Rosello A, Bataller L, Piñana JL, Montoro J, Lorenzo I, Villalba A, Freiria C, Santiago M, Sevilla T, Muelas N, Guerreiro M, Carretero C, Gómez I, Solves P, Sanz MÁ, Sanz G, Sanz J.

doi: 10.3324/haematol.2019.225078

Unique clinico-biological, genetic and prognostic features of adult early T cell precursor acute lymphoblastic leukemia.

Genescà E, Morgades M, Montesinos P, Barba P, Gil C, Guàrdia R, Moreno MJ, Martínez-Carballeira D, García-Cadenas I, Vives S, Ribera J, González-Campos J, González-Gil C, Zamora L, Ramírez JL, Díaz-Beya M, Mercadal S, Artola MT, Cladera A, Tormo M, Bermúdez A, Vall-Llovera F, Martínez P, Amigo ML, Monsalvo S, Novo A, Cervera M, García-Guiñon A, Juncà J, Ciudad J, Orfao A, Ribera JM

doi: 10.1200/JCO.19.00416

Chromosomal Abnormalities and Prognosis in NPM1-Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts

Angenendt L, Röllig C, Montesinos P, Martínez-Cuadrón D, Barragan E, García R, Botella C, Martínez P, Ravandi F, Kadia T, Kantarjian HM, Cortes J, Juliusson G, Lazarevic V, Höglund M, Lehmann S, Recher C, Pigneux A, Bertoli S, Dumas PY, Dombret H, Preudhomme C, Micol JB, Terré C, Ráčil Z, Novák J, Žák P, Wei AH, Tiong IS, Wall M, Estey E, Shaw C, Exeler R, Wagenführ L, Stölzel F, Thiede C, Stelljes M, Lenz G, Mikesch JH, Serve H, Ehninger G, Berdel WE, Kramer M, Krug U, Schliemann C

doi: 10.1182/blood.2019000239

Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia

Lucena-Araujo AR, Coelho-Silva JL, Pereira-Martins DA, Silveira DR, Koury LC, Melo RAM, Bittencourt R, Pagnano K, Pasquini R, Nunes EC, Fagundes EM, Gloria AB, Kerbauy F, de Lourdes Chauffaille M, Bendit I, Rocha V, Keating A, Tallman MS, Ribeiro RC, Dillon R, Ganser A, Löwenberg B, Valk PJM, Lo-Coco F, Sanz MA, Berliner N, Rego EM.

doi: 10.1016/j.clml.2019.07.116

Clinical Benefit of Glasdegib Plus Low-Dose Cytarabine in Patients with De Novo and Secondary Acute Myeloid Leukemia: Long-Term Analysis of a Phase 2 Randomized Trial

Heuser M, Fiedler W, Sekeres MA, Montesinos P, Leber B, Merchant A, Papayannidis C, Perez-Simon JA, Hoang CJ, Ma WW, Zeremski M, O'Connell A, Chan G, Cortes JE, Heuser M, Fiedler W, Sekeres MA, Leber B, Merchant A, Papayannidis C, Perez-Simon JA, Hoang CJ, Ma WW, Zeremski M, O'Connell A, Chan G, Cortes JE, Montesinos P

doi: 10.1016/j.clml.2019.07.097

Efficacy and Safety of Single-Agent Quizartinib, a Potent and Selective FLT3 Inhibitor (FLT3i), in Patients (pts) With FLT3-Internal Tandem Duplication (FLT3-ITD) – Mutated Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) Enrolled in the Global, Phase 3, Randomized Controlled QuANTUM-R Tria

Jonas BA, Cortes JE, Khaled SK, Martinelli G, Perl AE, Ganguly S, Russell NH, Kramer A, Dombret H, Hogge D, Leung AYH, Mehta P, Radsak MP, Sica S, Arunachalam M, Holmes M, Kobayashi K, Namuyinga R, Ge NX, Yver A, Zhang YF, Levis MJ, Montesinos P

doi: 10.1016/j.clml.2019.07.111

Low-Dose Cytarabine With or Without Glasdegib in Newly Diagnosed Patients with Acute Myeloid Leukemia: Long-Term Analysis of a Phase 2 Randomized Tria

Papayannidis C, Smith BD, Heuser M, Montesinos P, Sekeres MA, Oriol A, Schiller G, Candoni A, Jamieson C, Hoang CJ, Ma WW, Zeremski M, O'Connell A, Chan G, Cortes JE, Papayannidis C, Smith BD, Heuser M, Sekeres MA, Oriol A, Schiller G, Candoni A, Jamieson C, Hoang CJ, Ma WW, Zeremski M, O'Connell A, Chan G, Cortes JE, Montesinos P

doi: 10.1016/j.clml.2019.07.114

Glasdegib with LDAC in Newly Diagnosed Patients with Acute Myeloid Leukemia (AML) Unsuitable for Intensive Chemotherapy: Effects on Transfusions and Marrow Recovery vs LDAC Alone

Wang ES, Heuser M, Montesinos P, Sekeres MA, Merchant A, Olive CP, Salamero O, McCloskey JK, Hoang CJ, Ma WW, Zeremski M, O'Connell A, Chan G, Cortes JE, Wang ES, Heuser M, Sekeres MA, Merchant A, Olive CP, Salamero O, McCloskey JK, Hoan CJ, Ma WW, Zeremski M, O'Connell A, Chan G, Cortes JE, Montesinos P

doi: doi: 10.1007/s00430-019-00594-w

Kinetics of inflammatory biomarkers in plasma predict the occurrence and features of cytomegalovirus DNAemia episodes in allogeneic hematopoietic stem cell transplant recipients

Talaya A, Giménez E, Vinuesa V, Pérez A, Amat P, Piñana JL, Albert E, Hernández-Boluda JC, Solano C, Navarro D

doi: 10.1093/humrep/dez115

Dexamethasone does not prevent malignant cell reintroduction in leukemia patients undergoing ovarian transplant: risk assessment of leukemic cell transmission by a xenograft model.

Díaz-García C, Herraiz S, Such E, Andrés MDM, Villamón E, Mayordomo-Aranda E, Cervera JV, Sanz MA, Pellicer A.

doi: 10.1016/S1470-2045(16)30124-3

Lenalidomide plus dexamethasone versus observation in patients with high-risk smouldering multiple myeloma (QuiRedex): long-term follow-up of a randomised, controlled, phase 3 trial

Mateos MV, Hernández MT, Giraldo P, de la Rubia J, de Arriba F, Corral LL, Rosiñol L, Paiva B, Palomera L, Bargay J, Oriol A, Prosper F, López J, Arguiñano JM, Quintana N, García JL, Bladé J, Lahuerta JJ, Miguel JS.

doi: 10.1155/2019/4621416

Management of Adult Patients with Primary Immune Thrombocytopenia (ITP) in Clinical Practice: A Consensus Approach of the Spanish ITP Expert Group.

Mingot-Castellano ME, Román MTÁ, Fernández Fuertes LF, González-López TJ, Guinea de Castro JM, Jarque I, López-Fernández MF, Lozano ML, Sánchez González B, Ferreiras DV, González Porras JR.

doi: 10.3390/cancers11081196

Development, Implementation and Assessment of Molecular Diagnostics by Next Generation Sequencing in Personalized Treatment of Cancer: Experience of a Public Reference Healthcare Hospital.

Simarro J, Murria R, Pérez-Simó G, Llop M, Mancheño N, Ramos D, Juan I, Barragán E, Laiz B, Cases E, Ansótegui E, Gómez-Codina J, Aparicio J, Salvador C, Juan Ó, Palanca S.

doi: 10.1007/s00277-019-03663-5

Intravenous busulfan plus melphalan versus melphalan alone as conditioning regimen for patients with multiple myeloma

Blanes M, Lorenzo JI, Ribas P, Jiménez A, González JD, Cejalvo MJ, Solano C, Alegre A, de la Rubia J.

doi: 10.1002/cncr.32156

Incidence and outcome after first molecular versus overt recurrence in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia included in the ALL Ph08 trial from the Spanish PETHEMA Group

Ribera JM, García O, Moreno MJ, Barba P, García-Cadenas I, Mercadal S, Montesinos P, Barrios M, González-Campos J, Martínez-Carballeira D, Gil C, Ribera J, Vives S, Novo A, Cervera M, Serrano J, Lavilla E, Abella E, Tormo M, Amigo ML, Artola MT, Genescà E, Bravo P, García-Belmonte D, García-Guiñón A, Hernández-Rivas JM, Feliu E

doi: doi: 10.1016/S1470-2045(19)30150-0.

Quizartinib versus salvage chemotherapy in relapsed or refractory FLT3-ITD acute myeloid leukaemia (QuANTUM-R): a multicentre, randomised, controlled, open-label, phase 3 trial.

Cortes JE, Khaled S, Martinelli G, Perl AE, Ganguly S, Russell N, Krämer A, Dombret H, Hogge D, Jonas BA, Leung AY, Mehta P, Montesinos P, Radsak M, Sica S, Arunachalam M, Holmes M, Kobayashi K, Namuyinga R, Ge N, Yver A, Zhang Y, Levis MJ.

doi: doi: 10.1111/bjh.15887

The poor prognosis of low hypodiploidy in adults with B-cell precursor acute lymphoblastic leukaemia is restricted to older adults and elderly patients.

Ribera J, Granada I, Morgades M, Vives S, Genescà E, González C, Nomdedeu J, Escoda L, Montesinos P, Mercadal S, Coll R, González-Campos J, Abella E, Barba P, Bermúdez A, Gil C, Tormo M, Pedreño M, Martínez-Carballeira D, Hernández-Rivas JM, Orfao A, Martínez-López J, Esteve J, Bravo P, Garcia-Guiñon A, Debén G, Moraleda JM, Queizán JA, Ortín X, Moreno MJ, Feliu E, Solé F, Ribera JM; PETHEMA Group, Spanish Society of Haematology.

doi: doi: 10.1097/QAD.0000000000002209

Allogeneic stem-cell transplantation in HIV-1-infected patients with high-risk hematological disorders.

Kwon M, Bailén R, Balsalobre P, Jurado M, Bermudez A, Badiola J, Esquirol A, Miralles P, López-Fernández E, Sanz J, Yañez L, Colorado M, Piñana JL, Dorado N, Solán L, Martínez Laperche C, Buño I, Anguita J, Serrano D, Díez-Martin JL; Grupo Español de Trasplante Hematopoyético y Terapia Celular (GETH).

doi: doi: 10.1016/j.hemonc.2019.06.001

Autologous stem cell transplantation may be curative for patients with follicular lymphoma with early therapy failure without the need for immunotherapy.

Jiménez-Ubieto A, Grande C, Caballero D, Yáñez L, Novelli S, Hernández-Garcia MT, Manzanares M, Arranz R, Ferreiro JJ, Bobillo S, Mercadal S, Galeo A, Jiménez JL, Moraleda JM, Vallejo C, Albo C, Pérez E, Marrero C, Magnano L, Palomera L, Jarque I, Rodriguez A, Lorza L, Martín A, Coria E, López-Guillermo A, Salar A, José Lahuerta J; GELTAMO (Grupo Español de Linfomas y Trasplantes de Médula Ósea) Cooperative Study Group.

doi: 10.1007/s11239-019-01911-z

Next generation sequencing in bleeding disorders: two novel variants in the F5 gene (Valencia-1 and Valencia-2) associated with mild factor V deficiency.

Moret A, Zúñiga Á, Ibáñez M, Cid AR, Haya S, Ferrando F, Blanquer A, Cervera J, Bonanad S

doi: 10.3324/haematol.2018.212332

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry.

Hoeks M, Yu G, Langemeijer S, Crouch S, de Swart L, Fenaux P, Symeonidis A,Čermák J, Hellström-Lindberg E, Sanz G, Stauder R, Holm MS, Mittelman M, Mądry K, Malcovati L, Tatic A, Almeida AM, Germing U, Savic A, Gredelj Šimec N, Culligan D, Itzykson R, Guerci-Bresler A, Slama B, van de Loosdrecht A, van Marrewijk C, Droste J, Blijlevens N, van Kraaij M, Bowen D, de Witte T, Smith A

doi: 10.1001/jama.2019.9053

Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation A Randomized Clinical Trial

Bastidas A, de la Serna J, El Idrissi M, Oostvogels L, Quittet P, López-Jiménez J, Vural F, Pohlreich D, Zuckerman T, Issa NC, Gaidano G, Lee JJ, Abhyankar S, Solano C, Perez de Oteyza J, Satlin MJ, Schwartz S, Campins M, Rocci A, Vallejo Llamas C, Lee DG, Tan SM, Johnston AM, Grigg A, Boeckh MJ, Campora L, Lopez-Fauqued M, Heineman TC, Stadtmauer EA, Sullivan KM, ZOE-HSCT Study Group Collaborators (Isidro Jarque)

doi: 10.1182/blood-2019-124849

Post-transplant cyclophosphamide for GVHD prophylaxis in matched unrelated donor transplantation

Bailen R, Pascual-Cascon MJ, Balsalobre P, Sanz J, Doblas-Marquez A, Benitez-Hidalgo O, Pinana JL, Bento L, Sampol A, Oarbeascoa G, Solan L, Dorado N, Martinez-Laperche C, Anguita J, Buno I, Diez-Martin JL, Kwon M, Bailen R, Pascual-Cascon MJ, Balsalobre P, Doblas-Marquez A, Benitez-Hidalgo O, Bento L, Sampol A, Oarbeascoa G, Solan L, Dorado N, Martinez-Laperche C, Anguita, J, Buno I, Diez-Martin JL, Kwon M, Sanz J, Pinana JL

Safety and efficacy of the BCR inhibitors after allogeneic stem cell transplantation for CLL

Yanez L, Ferra C, Alcoceba M, Gonzalez M, Andreu R, Espigado I, Loscertales J, Marco JAG, Terol MJ, Solano C, Bosch F, Yanez L, Ferra C, Alcoceba M, Gonzalez M, Espigado I, Loscertales J, Marco JAG, Terol MJ, Bosch F, Andreu R, Solano C

Intravenous busulphan plus melphalan versus melphalan alone as conditioning regimen for newly diagnosed patients with multiple myeloma: Long-term follow-up of a matched case-controlled study

Blanes M, Lorenzo JI, Ribas P, Jimenez A, Gonzalez JD, Cejalvo MJ, Solano C, Alegre A, de la Rubia J, Ribas P, Jimenez A, Gonzalez JD, Cejalvo MJ, Alegre A, Blanes M, Lorenzo JI, Solano C, de la Rubia J

Allogeneic hsct in HIV-1 infected patients with hematological disorders: Multicenter experience from GETH (Spanish group of HSCT and cell therapy)

Kwon M, Bailen R, Balsalobre P, Jurado M, Bermudez A, Badiola J, Esquirol A, Miralles P, Lopez-Fernandez E, Yanez L, Colorado M, Sanz J, Pinana JL, Dorado N, Solan L, Martinez-Laperche C, Buno I, Anguita J, Diez-Martin JL, Kwon M, Bailen R, Balsalobre P, Jurado M, Bermudez A, Badiola J, Esquirol A, Miralles P, Lopez-Fernandez E, Yanez L, Colorado M, Dorado N, Solan L, Martinez-Laperche C, Buno I, Anguita J, Diez-Martin JL, Sanz J, Pinana JL

Haploidentical non-manipulated stem cell transplant in patients with non-hodgkin lymphoma: Spanish experience

Dorado N, Kwon M, Solano C, Ortega IS, Corral LL, Ferra C, Heras I, Cascon MJ, Cabrera R, Bermudez A, Montesinos P, Sampol A, Simon JAP, Martin C, Jimbra S, Herrera P, Humala K, Noriega V, Diez-Martin JL, Dorado N, Kwon M, Ortega IS, Corral LL, Ferra C, Heras I, Cascon MJ, Cabrera R, Bermudez A, Sampol A, Simon JAP, Martin C, Jimbra S, Humala K, Noriega V, Diez-Martin JL, Solano C, Montesinos P, Herrera P

doi: 10.1158/1538-7445.AM2019-CT184

Gilteritinib significantly prolongs overall survival in patients with FLT3-mutated (FLT3mut+) relapsed/refractory (R/R) acute myeloid leukemia (AML): Results from the Phase III ADMIRAL trial

Perl AE, Martinelli G, Cortes JE, Neubauer A, Berman E, Paolini S, Montesinos P, Baer MR, Larson RA, Ustun C, Fabbiano F, Di Stasi A, Stuart R, Olin R, Kasner M, Ciceri F, Chou WC, Podoltsev N, Recher C, Yokoyama H, Hosono N, Yoon SS, Lee JH, Pardee T, Fathi AT, Liu CF, Liu X, Bahceci E, Levis MJ, Perl AE, Martinelli G, Cortes JE, Neubauer A, Berman E, Paolini S, Baer MR, Larson RA, Ustun C, Fabbiano F, Di Stasi A, Stuart R, Olin R, Kasner M, Ciceri F, Chou WC, Podoltsev N, Recher C, Yokoyama H, Hosono N, Yoon SS, Lee JH, Pardee T, Fathi AT, Liu CF, Liu X, Bahceci E, Levis MJ, Montesinos P

doi: 10.1007/s41669-018-0098-8Epub ahead of print

Time and Cost of Hospitalisation for Salvage Therapy in Adults with Philadelphia Chromosome-Negative B Cell Precursor Relapsed or Refractory Acute Lymphoblastic Leukaemia in Spain. Pharmacoecon Open

Boluda B, Rodríguez-Veiga R, Martínez-Cuadrón D, Lorenzo I, Sanz J, Regadera A, Sempere A, Senent L, Cervera JV, Solves P, Reitan J, Gea S, Sanz MA, Montesinos P

doi: doi: 10.1111/ejh.13270. [Epub ahead of print]

Comparison of transfusion requirements in adult patients undergoing Haploidentical or single-unit umbilical cord blood stem cell transplantation.

Solves P, Sanz J, Gómez I, de la Puerta R, Arnao M, Montoro J, Piñana JL, Carretero C, Balaguer A, Guerreiro M, Andreu R, Rodríguez R, Montesinos P, Jarque I, Lorenzo JI, Carpio N, Sanz MÁ, Sanz GF

doi: doi: 10.1016/j.critrevonc.2019.03.003.

Challenges in the diagnosis and treatment of secondary acute myeloid leukemia.

Ossenkoppele G, Montesinos P.

doi: doi: 10.1111/ejh.13226.

Frequency, characteristics, and outcome of PTLD after allo-SCT: A multicenter study from the Spanish group of blood and marrow transplantation (GETH).

García-Cadenas I, Yáñez L, Jarque I, Martino R, Pérez-Simón JA, Valcárcel D, Sanz J, Bermúdez A, Muñoz C, Calderón-Cabrera C, García E, Alonso L, Suárez-Lledó M, González Vicent M, Heras I, Viguria MC, Batlle M, Vázquez L, López J, Solano C; Spanish group of blood and marrow transplantation (GETH).

doi: doi: 10.1111/ajt.15515

Cytomegalovirus (CMV) infection and risk of mortality in allogeneic hematopoietic stem cell transplantation (Allo-SCT): A systematic review, meta-analysis and meta-regression analysis.

Giménez E, Torres I, Albert E, Piñana JL, Hernández-Boluda JC, Solano C, Navarro D.

doi: doi: 10.1097/FTD.0000000000000657

Pharmacokinetic/pharmacodynamic analysis of voriconazole against Candida spp. and Aspergillus spp. in allogeneic stem cell transplant recipients.

Perez-Pitarch A, Guglieri-Lopez B, Ferriols-Lisart R, Pérez A, Ezquer-Garín C, Hernández-Boluda JC, Piñana JL, Navarro D, Solano C, Alós-Almiñana M.

doi: doi: 10.1002/jmv.25426

Spontaneously-resolving episodes of cytomegalovirus DNAemia in allogeneic hematopoietic stem cell transplant recipients: Virological features and clinical outcomes.

Talaya A, Giménez E, Piñana JL, Albert E, Hernández-Boluda JC, Pérez A, Torres I, Solano C, Navarro D.

doi: 10.1016/j.thromres.2019.06.015.

Clinical and molecular characterization by next generation sequencing of Spanish patients affected by congenital deficiencies of fibrinogen.

Moret A, Zúñiga Á, Ibáñez M, Cid AR, Haya S, Ferrando F, Blanquer A, Cervera J, Bonanad S

doi: doi: 10.1016/j.jinf.2019.04.006.

Lymphopenic community-acquired pneumonia is associated with a dysregulated immune response and increased severity and mortality.

Méndez R, Menéndez R, Amara-Elori I, Feced L, Piró A, Ramírez P, Sempere A, Ortega A, Bermejo-Martín JF, Torres A.

doi: doi: 10.3324/haematol.2018.212217

Impact of red blood cell transfusion dose density on progression-free survival in lower-risk myelodysplastic syndromes patients.

de Swart L, Crouch S, Hoeks M, Smith A, Langemeijer S, Fenaux P, Symeonidis A, Čermák J, Hellström-Lindberg E, Stauder R, Sanz G, Mittelman M, Holm MS, Malcovati L, Mądry K, Germing U, Tatic A, Savic A, Almeida AM, Gredelj-Šimec N, Guerci-Bresler A, Beyne-Rauzy O, Culligan D, Kotsianidis I, Itzykson R, van Marrewijk C, Blijlevens N, Bowen D, de Witte T; EUMDS Registry Participants.

doi: 10.1007/s00277-019-03744-5

Incidence and outcome of invasive fungal disease after front-line intensive chemotherapy in patients with acute myeloid leukemia: impact of antifungal prophylaxis.

Rodríguez-Veiga R, Montesinos P, Boluda B, Lorenzo I, Martínez-Cuadrón D, Salavert M, Pemán J, Calvillo P, Cano I, Acuña E, Villalba A, Piñana JL, Sanz J, Solves P, Senent L, Vicente A, Sempere A, Cervera J, Barragán E, Jarque I, Torres A, Sanz MA, Sanz GF.

doi: 10.2147/BLCTT.S177913

IDH1-mutated relapsed or refractory AML: current challenges and future prospects.

Megías-Vericat JE, Ballesta-López O, Barragán E, Montesinos P

doi: 10.1093/nar/gkz195

Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment

Urdinguio RG, Lopez V, Bayón GF, Diaz de la Guardia R, Sierra MI, García-Toraño E, Perez RF, García MG, Carella A, Pruneda PC, Prieto C, Dmitrijeva M, Santamarina P, Belmonte T, Mangas C, Diaconu E, Ferrero C, Tejedor JR, Fernandez-Morera JL, Bravo C, Bueno C, Sanjuan-Pla A, Rodriguez RM, Suarez-Alvarez B, López-Larrea C, Bernal T, Colado E, Balbín M, García-Suarez O, Chiara MD, Sáenz-de-Santa-María I, Rodríguez F, Pando-Sandoval A, Rodrigo L, Santos L, Salas A, Vallejo-Díaz J, C Carrera A, Rico D, Hernández-López I, Vayá A, Ricart JM, Seto E, Sima-Teruel N, Vaquero A, Valledor L, Cañal MJ, Pisano D, Graña-Castro O, Thomas T, Voss AK, Menéndez P, Villar-Garea A, Deutzmann R, Fernandez AF, Fraga MF

doi: 10.1016/j.transci.2019.04.007

Therapeutic plasma exchange: Review of current indications

Fernández-Zarzoso M, Gómez-Seguí I, de la Rubia J

doi: 10.1038/s41422-019-0162-7

Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy

Mugoni V, Panella R, Cheloni G, Chen M, Pozdnyakova O, Stroopinsky D, Guarnerio J, Monteleone E, Lee JD, Mendez L, Menon AV, Aster JC, Lane AA, Stone RM, Galinsky I, Zamora JC, Lo-Coco F, Bhasin MK, Avigan D, Longo L, Clohessy JG, Pandolfi PP

doi: doi: 10.1159/000497348.

RNA Sequencing Analysis for the Identification of a PCM1/PDGFRB Fusion Gene Responsive to Imatinib.

Such E, Liquori A, Mora E, Marco-Ayala J, Avetisyan G, Regadera A, Ibañez F, Panadero J, Senent L, Llop M, Díaz A, Vicente A, Luna I, Ibáñez M, Barragán E, Sanz MA, Sanz G, Cervera J.

doi: doi: 10.1080/10428194.2019.1607327

Real life outcomes of patients aged ≥75 years old with acute promyelocytic leukemia: experience of the PETHEMA registry.

Salamero O, Martínez-Cuadrón D, Sobas M, Benavente C, Vives S, De la Serna J, Pérez-Encinas M, Escoda L, Gil C, Brunet S, Ramos F, Esteve J, Amigo M, Krsnik I, Manso F, Arias J, González-Campos J, Serrano J, Oleksiuk J, Barrios M, García-Boyero R, Novo A, Sanz MA, Montesinos P; PETHEMA and PALG Groups.

doi: doi: 10.1016/j.jinf.2019.02.009

Pulmonary cytomegalovirus (CMV) DNA shedding in allogeneic hematopoietic stem cell transplant recipients: Implications for the diagnosis of CMV pneumonia.

Piñana JL, Giménez E, Gómez MD, Pérez A, González EM, Vinuesa V, Hernández-Boluda JC, Montoro J, Salavert M, Tormo M, Amat P, Moles P, Carretero C, Balaguer-Roselló A, Sanz J, Sanz G, Solano C, Navarro D.

doi: doi: 10.1093/cid/ciy792.

Clinical Effectiveness of Influenza Vaccination After Allogeneic Hematopoietic Stem Cell Transplantation: A Cross-sectional, Prospective, Observational Study.

Piñana JL, Pérez A, Montoro J, Giménez E, Gómez MD, Lorenzo I, Madrid S, González EM, Vinuesa V, Hernández-Boluda JC, Salavert M, Sanz G, Solano C, Sanz J, Navarro D

doi: doi: 10.1016/j.bbmt.2019.01.012.

Effect of Sirolimus Exposure on the Need for Preemptive Antiviral Therapy for Cytomeglovirus Infection after Allogeneic Hematopoietic Stem Cell Transplantation.

Guglieri-Lopez B, Perez-Pitarch A, Garcia-Cadenas I, Gimenez E, Barba P, Rabella N, Hernandez-Boluda JC, Fox L, Valcarcel D, Esquirol A, Ferriols-Lisart R, Sierra J, Solano C, Navarro D, Martino R, Piñana JL.

doi: doi: 10.1016/j.diagmicrobio.2018.11.012.

Factors influencing cytomegalovirus DNA load measurements in whole blood and plasma specimens from allogeneic hematopoietic stem cell transplant recipients.

Vinuesa V, Giménez E, Solano C, Albert E, Torres I, Pérez A, Hernández-Boluda JC, Piñana JL, Navarro D.

doi: doi: 10.3324/haematol.2018.211359

CRISPR to fix bad blood: a new tool in basic and clinical hematology.

González-Romero E, Martínez-Valiente C, García-Ruiz C, Vázquez-Manrique RP, Cervera J, Sanjuan-Pla A

doi: doi: 10.1016/j.colsurfb.2019.01.050.

Biomimetic microspheres for 3D mesenchymal stem cell culture and characterization.

Clara-Trujillo S, Marín-Payá JC, Cordón L, Sempere A, Gallego Ferrer G, Gómez Ribelles JL.

doi: doi: 10.1038/s41409-019-0582-5

Hematopoietic stem cell transplantation with unrelated cord blood or haploidentical donor grafts in adult patients with secondary acute myeloid leukemia, a comparative study from Eurocord and the ALWP EBMT.

Ruggeri A, Labopin M, Savani B, Paviglianiti A, Blaise D, Volt F, Ciceri F, Bacigalupo A, Tischer J, Chevallier P, Koc Y, Cornelissen JJ, Ehninger G, Sanz G, Deconinck E, Rocha V, Baron F, Mohty M, Gluckman E, Nagler A.

doi: 10.1111/myc.12891

Validation of a multivariable prediction model for post-engraftment invasive fungal disease in 465 adult allogeneic hematopoietic stem cell transplant recipients.

Rodríguez-Veiga R, Montesinos P, García E, Boluda B, Rojas R, Serrano J, Martínez-Cuadrón D, Martín C, Sanz J, Tabares S, Piñana JL, Lorenzo I, Montoro J, Salavert M, Pemán J, Jarque I, Solves P, Sanz GF, Torres A, Sanz MA

doi: 10.1200/JCO.2019.37.15_suppl.7000

Effect of gilteritinib on survival in patients with FLT3-mutated (FLT3(mut+)) relapsed/refractory (RR) AML who have common AML co-mutations or a high FLT3-ITD allelic ratio

Levis MJ, Perl AE, Martinelli G, Cortes JE, Neubauer A, Berman E, Montesinos P, Baer MR, Larson RA, Chou WC, Yokoyama H, Recher C, Yoon SS, Hill JE, Rosales M, Liu C, Bahceci E, Levis MJ, Perl AE, Martinelli G, Cortes JE, Neubauer A, Berman E, Baer MR, Larson RA, Chou WC, Yokoyama H, Recher C, Yoon SS, Hill JE, Rosales M, Liu C, Bahceci E, Montesinos P

doi: 10.1200/JCO.2019.37.15_suppl.TPS7063

MIRROS: An ongoing randomized phase 3 trial of idasanutlin plus ARA-C in patients with relapsed or refractory acute myeloid leukemia

Montesinos P, Esteve J, Konopleva M, Martinelli G, Ottmann O, Rodriguez-Veiga R, Rollig C, Wei A, Vey N, Chiu I, Monnet A, Ott MG, Fenaux P, Esteve J, Konopleva M, Martinelli G, Ottmann O, Rollig C, Wei A, Vey N, Chiu I, Monnet A, Ott MG, Fenaux P, Montesinos P, Rodriguez-Veiga R

doi: 10.1200/JCO.2019.37.15_suppl.7010

Low-dose cytarabine with or without glasdegib in newly diagnosed patients with acute myeloid leukemia: Long-term analysis of a phase 2 randomized trial

Smith BD, Papayannidis C, Heuser M, Montesinos P, Sekeres MA, Oriol A, Schiller GJ, Candoni A, Jamieson CHM, Hoang CJ, Ma W, Zeremski M, O'Connell A, Chan G, Cortes JE, Smith BD, Papayannidis C, Heuser M, Sekeres MA, Oriol A, Schiller GJ, Candoni A, Jamieson CHM, Hoang CJ, Ma W, Zeremski M, O'Connell A, Chan G, Cortes JE, Montesinos P

doi: doi: 10.1007/s12325-019-00910-z

Clinician Concepts of Cure in Adult Relapsed and Refractory Philadelphia-Negative B Cell Precursor Acute Lymphoblastic Leukemia: A Delphi Study.

Bassan R, Hoelzer D, Thomas X, Montesinos P, Pavlu J, McKendrick J, Kudlac A, Barlev A, Barber B, Cong Z.

doi: doi: 10.1038/s41408-019-0204-x

Umbilical cord blood versus unrelated donor transplantation in adults with primary refractory or relapsed acute myeloid leukemia: a report from Eurocord, the Acute Leukemia Working Party and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the EBMT.

Baron F, Labopin M, Ruggeri A, Ehninger G, Bonifazi F, Stelljes M, Sanz J, Stuhler G, Bosi A, Kröger N, Van Lint MT, Ganser A, Forcade E, Mohty M, Gluckman E, Nagler A.

doi: doi: 10.1111/joim.12870

Cord blood transplantation is associated with good outcomes in secondary Acute Myeloid Leukaemia in first remission.

Baron F, Labopin M, Ruggeri A, Volt F, Mohty M, Blaise D, Chevallier P, Sanz J, Fegueux N, Cornelissen JJ, Rambaldi A, Savani BN, Gluckman E, Nagler A.

doi: doi: 10.1016/j.transci.2019.02.002

Results of two protocols for platelet transfusion in patients undergoing abo incompatible hematopoietic stem cell transplantation

Solves P, Diaz Á, Carretero C, Gómez I, Carpio N, Sanz G.

doi: doi: 10.1093/annonc/mdz009

Brentuximab vedotin and ESHAP is highly effective as second-line therapy for Hodgkin lymphoma patients (long-term results of a trial by the Spanish GELTAMO Group).

Garcia-Sanz R, Sureda A, de la Cruz F, Canales M, Gonzalez AP, Pinana JL, Rodriguez A, Gutierrez A, Domingo-Domenech E, Sanchez-Gonzalez B, Rodriguez G, Lopez J, Moreno M, Rodriguez-Salazar MJ, Jimenez-Cabrera S, Caballero MD, Martinez C.

doi: doi: 10.1093/infdis/jiy746

Failure of Cytomegalovirus-Specific CD8+ T Cell Levels at Viral DNAemia Onset to Predict the Eventual Need for Preemptive Antiviral Therapy in Allogeneic Hematopoietic Stem Cell Transplant Recipients.

Giménez E, Solano C, Piñana JL, Poch M, Mateo E, Albert E, Hernández-Boluda JC, Amat P, Remigia MJ, Pérez A, Navarro D.

doi: 10.1007/s00277-019-03751-6

Chronic graft-versus-host disease could ameliorate the impact of adverse somatic mutations in patients with myelodysplastic syndromes and hematopoietic stem cell transplantation.

Caballero JC, Sánchez Barba M, Hernández Sánchez JM, Such E, Janusz K, Sanz G, Cabrero M, Chillón C, Cervera J, Hurtado AM, Jerez A, Calderón Cabrera C, Valcárcel D, Lumbreras E, Abáigar M, López Cadenas F, Hernández Rivas JM, Del Cañizo MC, Díez Campelo M.

doi: 10.1016/j.molcel.2019.01.017

System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.

Garcia-Moreno M, Noerenberg M, Ni S, Järvelin AI, González-Almela E, Lenz CE, Bach-Pages M, Cox V, Avolio R, Davis T, Hester S, Sohier TJM, Li B, Heikel G, Michlewski G, Sanz MA, Carrasco L, Ricci EP, Pelechano V, Davis I, Fischer B, Mohammed S, Castello A.

doi: 10.1007/s00430-019-00586-w

Kinetics of Alphatorquevirus plasma DNAemia at late times after allogeneic hematopoietic stem cell transplantation

Albert E, Solano C, Giménez E, Focosi D, Pérez A, Macera L, Piñana JL, Mateo EM, Boluda JCH, Maggi F, Navarro D

doi: 10.3324/haematol.2017.180505

Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma

Recasens-Zorzo C, Cardesa-Salzmann T, Petazzi P, Ros-Blanco L, Esteve-Arenys A, Clot G, Guerrero-Hernández M, Rodríguez V, Soldini D, Valera A, Moros A, Climent F, González-Barca E, Mercadal S, Arenillas L, Calvo X, Mate JL, Gutiérrez-García G, Casanova I, Mangues R, Sanjuan-Pla A, Bueno C, Menéndez P, Martínez A, Colomer D, Tejedor RE, Teixidó J, Campo E, López-Guillermo A, Borrell JI, Colomo L, Pérez-Galán P, Roué G

doi: 10.1038/s41409-019-0516-2

Indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2019

Duarte RF, Labopin M, Bader P, Basak GW, Bonini C, Chabannon C, Corbacioglu S, Dreger P, Dufour C, Gennery AR, Kuball J, Lankester AC, Lanza F, Montoto S, Nagler A, Peffault de Latour R, Snowden JA, Styczynski J, Yakoub-Agha I, Kröger N, Mohty M;

doi: 10.1080/17512433.2019.1573668Epub 2019 Feb 6

Daunorubicin and cytarabine for certain types of poor-prognosis acute myeloid leukemia: a systematic literature review. Expert Rev Clin Pharmacol

Megías-Vericat JE, Martínez-Cuadrón D, Sanz MÁ, Poveda JL, Montesinos P

doi: 10.1016/j.jmoldx.2018.09.009Epub 2018 Dec 19

Clinical Utility of a Next-Generation Sequencing Panel for Acute Myeloid Leukemia Diagnostics. J Mol Diagn

Alonso CM, Llop M, Sargas C, Pedrola L, Panadero J, Hervás D, Cervera J, Such E, Ibáñez M, Ayala R, Martínez-López J, Onecha E, de Juan I, Palanca S, Martínez-Cuadrón D, Rodríguez-Veiga R, Boluda B, Montesinos P, Sanz G, Sanz MA, Barragán E

doi: doi: 10.4084/MJHID.2019.016. eCollection 2019.

Differences in ex-vivo Chemosensitivity to Anthracyclines in First Line Acute Myeloid Leukemia.

Megías-Vericat JE, Martínez-Cuadrón D, López JM, Bergua JM, Tormo M, Serrano J, González A, de Oteyza JP, Vives S, Vidriales B, Herrera P, Vera JA, Martínez AL, de la Fuente A, Amador ML, Hernández-Rivas JÁ, Fernández MÁ, Cerveró CJ, Morillo D, Campo PH, Gorrochategui J, Primo D, Rojas JL, Guenova M, Ballesteros J, Sanz M, Montesinos P.

doi: doi: 10.1016/j.eimc.2019.01.013

Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Network for Research in Infectious Diseases (REIPI) and the Spanish Society of Haematology and Haemotherapy (SEHH) on the management of febrile neutropenia in patients with hematological malignancies.

Gudiol C, Aguilar-Guisado M, Azanza JR, Candel FJ, Cantón R, Carratalà J, Garcia-Vidal C, Jarque I, Lizasoain M, Gil-Bermejo JM, Ruiz-Camps I, Sánchez-Ortega I, Solano C, Suárez-Lledó M, Vázquez L, de la Cámara R.

doi: doi: 10.1111/bjh.15713

Bendamustine as part of conditioning of autologous stem cell transplantation in patients with aggressive lymphoma: a phase 2 study from the GELTAMO group.

Redondo AM, Valcárcel D, González-Rodríguez AP, Suárez-Lledó M, Bello JL, Canales M, Gayoso J, Colorado M, Jarque I, Del Campo R, Arranz R, Terol MJ, Rifón JJ, Rodríguez MJ, Ramírez MJ, Castro N, Sánchez A, López-Jiménez J, Montes-Moreno S, Briones J, López A, Palomera L, López-Guillermo A, Caballero D, Martín A; Grupo Español de Linfomas y Trasplante Autólogo de Médula Ósea (GELTAMO).

doi: 10.3390/jcm8030311

VDR rs2228570 Polymorphism Is Related to Non-Progression to AIDS in Antiretroviral Therapy Naive HIV-Infected Patient

Jimenez-Sousa, MA, Jimenez, JL, Fernandez-Rodriguez, A, Brochado-Kith, O, Bellon, JM, Bernal-Morell, E, Munoz-Fernandez, MA, Resino, S, del Amo, J, Navarro, ML, Gonzalez, MI, Blanco, JL, Gonzalez, J, Del Amo, J, Jarrin, I, Alejos, B, Hernando, V, Moreno, C, Iniesta, C, Sousa, LMG, Perez, NS, Munoz-Fernandez, MA, Garcia-Merino, IM, Fernandez, IC, Rico, CG, de la Fuente, JG, Concejo, PP, Portilla, J, Merino, E, Reus, S, Boix, V, Giner, L, Gadea, C, Portilla, I, Pampliega, M, Diez, M, Rodriguez, JC, Sanchez-Paya, J, Gomez, JL, Hernandez, J, Aleman, MR, Alonso, MD, Hernandez, MI, Diaz-Flores, F, Garcia, D, Pelazas, R, Lirola, AL, Rubio, R, Pulido, F, Bisbal, O, Hernando, A, Dominguez, L, Crestelo, DR, Bermejo, L, Santacreu, M, Iribarren, JA, Arrizabalaga, J, Aramburu, MJ, Camino, X, Rodriguez-Arrondo, F, von Wichmann, MA, Tome, LP, Goenaga, MA, Bustinduy, MJ, Azkune, H, Ibarguren, M, Lizardi, A, Kortajarena, X, Gutierrez, F, Masia, M, Padilla, S, Navarro, A, Montolio, F, Robledano, C, Colome, JG, Adsuar, A, Pascual, R, Fernandez, M, Garcia, E, Garcia, JA, Barber, X, Berenguer, J, de Quiros, JCLB, Gutierrez, I, Ramirez, M, Padilla, B, Gijon, P, Aldamiz-Echevarria, T, Tejerina, F, Parras, FJ, Balsalobre, P, Diez, C, Latorre, LP, Vidal, F, Peraire, J, Vilades, C, Veloso, S, Vargas, M, Lopez-Dupla, M, Olona, M, Rull, A, Rodriguez-Gallego, E, Alba, V, Alonso, MM, Aldeguer, JL, Julia, MB, Pitarch, MT, Hernandez, IC, Munoz, EC, Tovar, SC, Lleti, MS, Navarro, JF, Gonzalez-garcia, J, Arnalich, F, Arribas, JR, de la Serna, JIB, Castro, JM, Escosa, L, Herranz, P, Hontanon, V, Garcia-Bujalance, S, Lopez-Hortelano, MG, Gonzalez-Baeza, A, Martin-Carbonero, ML, Mayoral, M, Mellado, MJ, Mican, RE, Montejano, R, Montes, ML, Moreno, V, Perez-Valero, I, Rodes, B, Sainz, T, Sendagorta, E, Alcariz, NS, Valencia, E, Blanco, JR, Oteo, JA, Ibarra, V, Metola, L, Sanz, M, Perez-Martinez, L, Dalmau, D, Jaen, A, Sanmarti, M, Cairo, M, Martinez-Lacasa, J, Velli, P, Font, R, Xercavins, M, Alonso, N, Rivero, M, Reparaz, J, de Alda, MGR, Cano, MTD, de Galarreta, BPR, Segura, F, Amengual, MJ, Navarro, G, Sala, M, Cervantes, M, Pineda, V, Calzado, S, Navarro, M, de los Santos, I, Sanz, JS, Aparicio, AS, Cepeda, CS, Fraile, LGF, Gayo, EM, Moreno, S, Casado, JL, Dronda, F, Moreno, A, Elias, MJP, Ayerbe, CG, Gutierrez, C, Madrid, N, Terron, SD, Marti, P, Ansa, U, Serrano, S, Vivancos, MJ, Bernal, E, Cano, A, Garcia, AA, Urbieta, JB, Munoz, A, Alcaraz, MJ, Villalba, MD, Garcia, F, Hernandez, J, Pena, A, Munoz, L, Casas, P, Alvarez, M, Chueca, N, Vinuesa, D, Martinez-Montes, C, Del Romero, J, Rodriguez, C, Puerta, T, Carrio, JC, Vera, M, Ballesteros, J, Ayerdi, O, Riera, M, Penaranda, M, Leyes, M, Ribas, MA, Campins, AA, Vidal, C, Fanjul, F, Murillas, J, Homar, F, Santos, J, Ayerbe, CG, Viciana, I, Palacios, R, Gonzalez, CM, Viciana, P, Espinosa, N, Lopez-Cortes, LF, Podzamczer, D, Ferrer, E, Imaz, A, Tiraboschi, J, Silva, A, Saumoy, M, Olalla, J, del Arco, A, de la Torre, J, Prada, JL, Guerrero, JMGD, Stachowski, JP, Martinez, OJ, Vera, FJ, Martinez, L, Garcia, J, Alcaraz, B, Jimeno, A, Iglesias, AC, Souto, BP, de Cea, AM, Galera, C, Albendin, H, Perez, A, Iborra, A, Moreno, A, Merlos, MA, Vidal, A, Suarez-Garcia, I, Malmierca, E, Gonzalez-Ruano, P, Rodrigo, DM, Mohamed-Balghata, MO, Vidal, MAG, Perez, VE, Molina, MJT, Garcia, JV, Moreno, JPS, Gorgolas, M, Cabello, A, Alvarez, B, Prieto, L, Moreno, JS, Caso, AA, Gutierrez, CH, Mena, MN, Puerto, MJG, Vilalta, RF, Ribera, AF, Roman, AR, Herrero, MTB, Juarez, AR, Lopez, PL, Sanchez, IM, Martinez, JP, Jimenez, MC, Perea, RT, Ruiz-Capillas, JJJ, Pineda, JA, CoRIS, Spanish HIV HGM BioBank, LTNPs Cohort, Jimenez-Sousa, MA, Jimenez, JL, Fernandez-Rodriguez, A, Brochado-Kith, O, Bellon, JM, Bernal-Morell, E, Munoz-Fernandez, MA, Resino, S, del Amo, J, Navarro, ML, Gonzalez, MI, Blanco, JL, Gonzalez, J, Del Amo, J, Jarrin, I, Alejos, B, Hernando, V, Moreno, C, Iniesta, C, Sousa, LMG, Perez, NS, Munoz-Fernandez, MA, Garcia-Merino, IM, Fernandez, IC, Rico, CG, de la Fuente, JG, Concejo, PP, Portilla, J, Merino, E, Reus, S, Boix, V, Giner, L, Gadea, C, Portilla, I, Pampliega, M, Diez, M, Rodriguez, JC, Sanchez-Paya, J, Gomez, JL, Hernandez, J, Aleman, MR, Alonso, MD, Hernandez, MI, Diaz-Flores, F, Garcia, D, Pelazas, R, Lirola, AL, Rubio, R, Pulido, F, Bisbal, O, Hernando, A, Dominguez, L, Crestelo, DR, Bermejo, L, Santacreu, M, Iribarren, JA, Arrizabalaga, J, Aramburu, MJ, Camino, X, Rodriguez-Arrondo, F, von Wichmann, MA, Tome, LP, Goenaga, MA, Bustinduy, MJ, Azkune, H, Ibarguren, M, Lizardi, A, Kortajarena, X, Gutierrez, F, Masia, M, Padilla, S, Navarro, A, Montolio, F, Robledano, C, Colome, JG, Adsuar, A, Pascual, R, Fernandez, M, Garcia, E, Garcia, JA, Barber, X, de Quiros, JCLB, Gutierrez, I, Ramirez, M, Padilla, B, Gijon, P, Aldamiz-Echevarria, T, Tejerina, F, Parras, FJ, Balsalobre, P, Diez, C, Latorre, LP, Vidal, F, Peraire, J, Vilades, C, Veloso, S, Vargas, M, Lopez-Dupla, M, Olona, M, Rull, A, Rodriguez-Gallego, E, Alba, V, Julia, MB, Hernandez, IC, Tovar, SC, Navarro, JF, Gonzalez-garcia, J, Arnalich, F, Arribas, JR, de la Serna, JIB, Castro, JM, Escosa, L, Herranz, P, Hontanon, V, Garcia-Bujalance, S, Lopez-Hortelano, MG, Gonzalez-Baeza, A, Martin-Carbonero, ML, Mayoral, M, Mellado, MJ, Mican, RE, Montejano, R, Montes, ML, Moreno, V, Perez-Valero, I, Rodes, B, Sainz, T, Sendagorta, E, Alcariz, NS, Valencia, E, Blanco, JR, Oteo, JA, Ibarra, V, Metola, L, Perez-Martinez, L, Dalmau, D, Jaen, A, Sanmarti, M, Cairo, M, Martinez-Lacasa, J, Velli, P, Font, R, Xercavins, M, Rivero, M, Reparaz, J, de Alda, MGR, Cano, MTD, de Galarreta, BPR, Segura, F, Amengual, MJ, Navarro, G, Sala, M, Cervantes, M, Pineda, V, Calzado, S, Navarro, M, de los Santos, I, Sanz, JS, Aparicio, AS, Cepeda, CS, Fraile, LGF, Gayo, EM, Moreno, S, Casado, JL, Dronda, F, Moreno, A, Elias, MJP, Ayerbe, CG, Gutierrez, C, Madrid, N, Terron, SD, Ansa, U, Serrano, S, Vivancos, MJ, Bernal, E, Garcia, AA, Urbieta, JB, Alcaraz, MJ, Villalba, MD, Garcia, F, Hernandez, J, Pena, A, Munoz, L, Casas, P, Alvarez, M, Chueca, N, Vinuesa, D, Martinez-Montes, C, Del Romero, J, Rodriguez, C, Puerta, T, Carrio, JC, Vera, M, Ballesteros, J, Ayerdi, O, Riera, M, Penaranda, M, Leyes, M, Ribas, MA, Campins, AA, Vidal, C, Fanjul, F, Murillas, J, Homar, F, Santos, J, Ayerbe, CG, Viciana, I, Palacios, R, Gonzalez, CM, Viciana, P, Espinosa, N, Lopez-Cortes, LF, Podzamczer, D, Ferrer, E, Imaz, A, Tiraboschi, J, Silva, A, Saumoy, M, Olalla, J, del Arco, A, de la Torre, J, Prada, JL, Guerrero, JMGD, Stachowski, JP, Martinez, OJ, Vera, FJ, Martinez, L, Garcia, J, Alcaraz, B, Jimeno, A, Iglesias, AC, Souto, BP, de Cea, AM, Galera, C, Albendin, H, Iborra, A, Moreno, A, Merlos, MA, Vidal, A, Suarez-Garcia, I, Malmierca, E, Gonzalez-Ruano, P, Rodrigo, DM, Mohamed-Balghata, MO, Vidal, MAG, Perez, VE, Molina, MJT, Garcia, JV, Moreno, JPS, Gorgolas M, Cabello A, Alvarez B, Prieto L, Moreno JS, Caso AA, Gutierrez CH, Mena MN, Puerto MJG, Vilalta RF, Ribera AF, Roman AR, Herrero MTB, Juarez AR, Lopez PL, Sanchez IM, Martinez, JP, Jimenez, MC, Perea RT, Ruiz-Capillas JJJ, Pineda JA, CoRIS, Spanish HIV HGM BioBank, LTNPs Cohort, Berenguer J, Alonso MM, Aldeguer JL, Pitarch MT, Munoz EC, Lleti MS, Sanz M, Alonso N, Marti P, Cano A, Munoz A, Perez A

doi: 10.1038/s41375-018-0312-9Epub 2018 Dec 16

Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome

Cortes JE, Heidel FH, Hellmann A, Fiedler W, Smith BD, Robak T, Montesinos P, Pollyea DA, DesJardins P, Ottmann O, Ma WW, Shaik MN, Laird AD, Zeremski M, O'Connell A, Chan G, Heuser M

doi: 10.3324/haematol.2018.194712Epub 2018 Aug 9

A novel deep targeted sequencing method for minimal residual disease monitoring in acute myeloid leukemia. Haematologica

Onecha E, Linares M, Rapado I, Ruiz-Heredia Y, Martinez-Sanchez P, Cedena T, Pratcorona M, Oteyza JP, Herrera P, Barragan E, Montesinos P, Vela JAG, Magro E, Anguita E, Figuera A, Riaza R, Martinez-Barranco P, Sanchez-Vega B, Nomdedeu J, Gallardo M, Martinez-Lopez J, Ayala R

doi: 10.1182/blood-2019-01-894980Epub ahead of print

Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet. Blood

Sanz MA, Fenaux P, Tallman MS, Estey EH, Löwenberg B, Naoe T, Lengfelder E, Döhner H, Burnett AK, Chen SJ, Mathews V, Iland H, Rego E, Kantajian H, Adès L, Avvisati G, Montesinos P, Platzbecker U, Ravandi F, Russell NH, Lo-Coco F

doi: doi: 10.1200/JCO.18.00053

Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide.

Horwitz ME, Wease S, Blackwell B, Valcarcel D, Frassoni F, Boelens JJ, Nierkens S, Jagasia M, Wagner JE, Kuball J, Koh LP, Majhail NS, Stiff PJ, Hanna R, Hwang WYK, Kurtzberg J, Cilloni D, Freedman LS, Montesinos P, Sanz G.

doi: doi: 10.1016/j.leukres.2018

A precision medicine test predicts clinical response after idarubicin and cytarabine induction therapy in AML patients.

Martínez-Cuadrón D, Gil C, Serrano J, Rodríguez G, Pérez-Oteyza J, García-Boyero R, Jiménez-Bravo S, Vives S, Vidriales MB, Lavilla E, Pérez-Simón JA, Tormo M, Colorado M, Bergua J, López JA, Herrera P, Hernández-Campo P, Gorrochategui J, Primo D, Rojas JL, Villoria J, Moscardó F, Troconiz I, Linares Gómez M, Martínez-López J, Ballesteros J, Sanz M, Montesinos P; Spanish PETHEMA group.

doi: doi: 10.1111/ijlh.12933.

Hidden myelodysplastic syndrome (MDS): A prospective study to confirm or exclude MDS in patients with anemia of uncertain etiology.

Bastida JM, López-Godino O, Vicente-Sánchez A, Bonanad-Boix S, Xicoy-Cirici B, Hernández-Sánchez JM, Such E, Cervera J, Caballero-Berrocal JC, López-Cadenas F, Arnao-Herráiz M, Rodríguez I, Llopis-Calatayud I, Jiménez MJ, Del Cañizo-Roldán MC, Díez-Campelo M.

doi: 10.1007/s00408-018-0186-7

Cytotoxic Natural Killer Subpopulations as a Prognostic Factor of Malignant Pleural Effusion

Herrera Lara S, Fernández-Fabrellas E, Juan Samper G, Marco Buades J, Andreu Lapiedra R, Pinilla Moreno A, Morales Suárez-Varela M.

Decitabine as Salvage Therapy after Azacitidine in AML

De La Fuente A, Beneit P, Gama AM, Mayol AS, Gonzalez KJ, de Dios LC, Valls JD, Perez AR, Figuera A, Lekue CB, Oiartzabal I, Ordonez SS, Polo SV, Chamorro CM, Jorda RC, Brunet S, Foncillas MA, Gonzalez B, Lopez AD, Montesinos P, De La Fuente A, Beneit P, Gama AM, Mayol AS, Gonzalez KJ, de Dios LC, Valls JD, Perez AR, Figuera A, Lekue CB, Oiartzabal I, Ordonez SS, Polo SV, Chamorro CM, Jorda RC, Brunet S, Foncillas MA, Gonzalez B, Lopez AD, Montesinos P

Multicentre Implementation of Next Generation Sequencing to Acute Myeloid Leukemia Patients in PETHEMA Spanish Collaborative Group

Sargas C, Ayala R, Chillon C, Carrillo E, Larrayoz MJ, Bilbao C, Rodriguez-Veiga R, Rapado I, Garcia-Sanz R, Perez-Simon JA, Calasanz MJ, Gomez-Casares MT, Sanchez J, Juarez A, Gonzalez M, Garcia-Calderon C, Prosper F, Rodriguez C, Serrano J, Montesinos P, Martinez J, Barragan E, Ayala R, Chillon C, Carrillo E, Larrayoz MJ, Bilbao C, Rapado I, Garcia-Sanz R, Perez-Simon JA, Calasanz MJ, Gomez-Casares MT, Sanchez J, Juarez A, Gonzalez M, Garcia-Calderon C, Prosper F, Rodriguez C, Serrano J, Sargas C, Rodriguez-Veiga R, Montesinos P, Martinez J, Barragan E

Outcome of Acute Myeloid Leukemia with Inv(3)(Q21q26.2)/ T(3;3)(Q21;Q26.2). Experience of the Spanish PETHEMA and CETLAM Groups

Sitges M, Boluda B, Garrido A, Morgades M, Arnan M, Serrano J, Tormo M, Colorado M, Bergua JM, Salamero O, Esteve J, Benavente C, Perez-Encinas M, Coll R, Marti-Tutusaus JMM, Ribera JM, Brunet S, Sierra J, Sanz MA, Montesinos P, Vives S, PETHEMA Cooperative Grp, CETLAM Cooperative Grp, Sitges M, Garrido A, Morgades M, Arnan M, Serrano J, Tormo M, Colorado M, Bergua JM, Salamero O, Esteve J, Perez-Encinas M, Coll R, Marti-Tutusaus JMM, Ribera JM, Brunet S, Sierra J, Vives S, PETHEMA Cooperative Grp, CETLAM Cooperative Grp, Boluda B, Benavente C, Sanz MA, Montesinos P

doi: 10.1080/10428194.2018.1468893Epub 2018 Jul 2

Performance of the Medical Research Council (MRC) and the Leukemia Research Foundation (LRF) score in predicting survival benefit with hypomethylating agent use in patients with relapsed or refractory acute myeloid leukemia. Leuk Lymphoma

Stahl M, DeVeaux M, Montesinos P, Itzykson R, Ritchie EK, Sekeres MA, Barnard J, Podoltsev NA, Brunner A, Komrokji RS, Bhatt VR, Al-Kali A, Cluzeau T, Santini V, Roboz GJ, Fenaux P, Litzow M, Fathi AT, Perreault S, Kim TK, Prebet T, Vey N, Verma V, Germing U, Bergua J, Serrano J, Gore SD, Zeidan AM

doi: doi: 10.1111/ejh.13178

Increased survival due to lower toxicity for high-risk T-cell acute lymphoblastic leukemia patients in two consecutive pediatric-inspired PETHEMA trials.

Barba P, Morgades M, Montesinos P, Gil C, Fox ML, Ciudad J, Moreno MJ, González-Campos J, Genescà E, Martínez-Carballeira D, Martino R, Vives S, Guardia R, Mercadal S, Artola MT, Cladera A, Tormo M, Esteve J, Bergua J, Vall-Llovera F, Ribera J, Martínez-Sanchez P, Amigo ML, Bermúdez A, Calbacho M, Hernández-Rivas JM, Feliu E, Orfao A, Ribera JM.

doi: doi: 10.3390/proteomes7010002.

Challenges in Clinical Metaproteomics Highlighted by the Analysis of Acute Leukemia Patients with Gut Colonization by Multidrug-Resistant Enterobacteriaceae.

Rechenberger J, Samaras P, Jarzab A, Behr J, Frejno M, Djukovic A, Sanz J, González-Barberá EM, Salavert M, López-Hontangas JL, Xavier KB, Debrauwer L, Rolain JM, Sanz M, Garcia-Garcera M, Wilhelm M, Ubeda C, Kuster B.

doi: doi: 10.1038/s41409-018-0251-0

Pre-engraftment cytomegalovirus DNAemia in allogeneic hematopoietic stem cell transplant recipients: incidence, risk factors, and clinical outcomes.

Solano C, Giménez E, Albert E, Mateo EM, Gómez M, Goterris R, Pérez A, Amat P, Hernández-Boluda JC, Poch M, Piñana JL, Navarro D.

doi: doi: 10.1002/cyto.b.21720

A reproducible strategy for analysis of minimal residual disease measured by Standardized multiparametric flow cytometry in b acute lymphoblastic leukemia.

Sarmiento Palao H, Tarín F, Martirena F, Barragán E, Such E, Sempere A, Tasso M, Manresa P, López F.

doi: 10.1080/21678707.2019.1652163

Development and validation of an MCDA framework for evaluation and decision-making of orphan drugs in

Badia, X., Chugani, D., Abad, M.R., Arias, P., Guillén-Navarro, E., Jarque, I., Posada, M., Vitoria, I., Poveda, J.L

doi: PMID: 32091828

Umbilical Cord Blood Transplantation in Children and Adults (Book Chapter)

Sanz J, Veys P, Rocha V

doi: 10.1080/10428194.2018.1522438Epub ahead of print

Clinical significance of complex karyotype at diagnosis in pediatric and adult patients with de novo acute promyelocytic leukemia treated with ATRA and chemotherapy. Leuk Lymphoma

Labrador J, Luño E, Vellenga E, Brunet S, González-Campos J, Chillón MC, Holowiecka A, Esteve J, Bergua J, González-Sanmiguel JD, Gil C, Tormo M, Salamero O, Manso F, Fernández I, de laSerna J, Moreno MJ, Pérez-Encinas M, Krsnik I, Ribera JM, Cervera J, Calasanz MJ, Boluda B, Sobas M, Lowenberg B, Sanz MA, Montesinos P

doi: 10.1111/ejh.13202Epub ahead of print

Invasive fungal disease in patients undergoing umbilical cord blood transplantation after myeloablative conditioning regimen. Eur J Haematol

Montoro J, Sanz J, Lorenzo JI, Montesinos P, Rodríguez-Veiga R, Salavert M, González E, Guerreiro M, Carretero C, Balaguer A, Gómez I, Solves P, Sanz GF, Sanz MA, Piñana JL

doi: 10.1097/HS9.0000000000000150

Diagnosis and Treatment of Chronic Myelomonocytic Leukemias in Adults: Recommendations From the European Hematology Association and the European LeukemiaNet.

Itzykson, Raphael; Fenaux, Pierre; Bowen, David; Cross, Nicholas C P; Cortes, Jorge; De Witte, Theo; Germing, Ulrich; Onida, Francesco; Padron, Eric; Platzbecker, Uwe; Santini, Valeria; Sanz, Guillermo F; Solary, Eric; Van de Loosdrecht, Arjan; Malcovati, Luca

doi: 10.1007/s12094-018-1889-1

Letter to the Editor

astel V, Cañete A, Calabria I, Cervera J, Dolz S, Escobar P, Font de Mora J, Gargallo P, Llavador G, Pedrola L, Yañez Y, Zuñiga A.

doi: 10.1371/journal.pone.020729

New mutations found by Next-Generation Sequencing screening of Spanish patients with Nemaline Myopathy

Moreau-Le Lan S, Aller E, Calabria I, Gonzalez-Tarancon L, Cardona-Gay C, Martinez-Matilla M, Aparisi MJ, Selles J, Sagath L, Pitarch I, Muelas N, Cervera JV, Millan JM, Pedrola L

doi: 10.1002/hon.2553

Autologous stem cell transplantation may be curative for patients with follicular lymphoma with early therapy failure who reach complete response after rescue treatment

Jiménez-Ubieto A, Grande C, Caballero D, Yáñez L, Novelli S, Hernández-Garcia MT, Manzanares M, Arranz R, Ferreiro JJ, Bobillo S, Mercadal S, Galeo A, Jiménez JL, Moraleda JM, Vallejo C, Albo C, Pérez E, Marrero C, Magnano L, Palomera L, Jarque I, Martínez-Sánchez P, Martín A, Coria E, López-Guillermo A, Salar A, Lahuerta JJ

doi: 10.1111/ajt.14754

Sirolimus exposure and the occurrence of cytomegalovirus DNAemia after allogeneic hematopoietic stem cell transplantation

Piñana JL, Perez-Pitarch A, Guglieri-Lopez B, Giménez E, Hernandez-Boluda JC, Terol MJ, Ferriols-Lisart R, Solano C, Navarro D

doi: 10.1186/s12885-018-5002-5

Testing for minimal residual disease in adults with acute lymphoblastic leukemia in Europe: a clinician survey. BMC Cancer

Pigneux A, Montesinos P, Cong Z, Zhang X, Pownell AK, Wieffer H, McKendrick J, Brüggemann M

doi: 10.3390/cancers10110436

Focal Adhesion Genes Refine the Intermediate-Risk Cytogenetic Classification of Acute Myeloid Leukemia. Cancers (Basel)

Pallarès V, Hoyos M, Chillón MC, Barragán E, Prieto Conde MI, Llop M, Falgàs A, Céspedes MV, Montesinos P, Nomdedeu JF, Brunet S, Sanz MÁ, González-Díaz M, Sierra J, Mangues R, Casanova I

doi: 10.1097/CCO.0000000000000486

Current management of patients with chronic myelomonocytic leukemia

Mora, Elvira; Sanz, Guillermo F.

doi: 10.1002/gcc.22667

Clonal architecture in patients with myelodysplastic syndromes and double or minor complex abnormalities: Detailed analysis of clonal composition, involved abnormalities, and prognostic significance

Schanz J, Solé F, Mallo M, Luño E, Cervera J, Granada I, Hildebrandt B, Slovak ML, Ohyashiki K, Fonatsch C, Pfeilstöcker M, Nösslinger T, Valent P, Giagounidis A, Aul C, Lübbert M, Stauder R, Krieger O, Le Beau MM, Bennett JM, Greenberg P, Germing U, Haase D.

doi: 10.1097/CCO.0000000000000481

T lymphocytes as therapeutic arsenal for patients with hematological malignancies

Montoro J, Piñana JL, Sanz J, Guerreiro M

doi: 10.1080/10428194.2018.1516875Epub ahead of print

An analysis of the impact of CD56 expression in de novo acute promyelocytic leukemia patients treated with upfront all-trans retinoic acid and anthracycline-based regimens. Leuk Lymphoma

Sobas M, Montesinos P, Boluda B, Bernal T, Vellenga E, Nomdedeu J, González-Campos J, Chillón M, Holowiecka A, Esteve J, Bergua J, González-Sanmiguel JD, Gil-Cortes C, Tormo M, Salamero O, Manso F, Fernández I, de la Serna J, Moreno MJ, Pérez-Encinas M, Krsnik I, Ribera JM, Escoda L, Lowenberg B, Sanz MA; PETHEMA, HOVON, PALG, and GATLA cooperative groups

doi: 10.1016/j.leukres.2018.08.022

Differing clinical features between Japanese and Caucasian patients with myelodysplastic syndromes: Analysis from the International Working Group for Prognosis of MDS

Miyazaki, Yasushi; Tuechler, Heinz; Sanz, Guillermo; Schanz, Julie; Garcia-Manero, Guillermo; Sole, Francesc; Bennett, John M.; Bowen, David; Fenaux, Pierre; Dreyfus, Francois; Kantarjian, Hagop; Kuendgen, Andrea; Malcovati, Luca; Cazzola, Mario; Cermak, Jaroslav; Fonatsch, Christa; Le Beau, Michelle M.; Slovak, Marilyn L.; Santini, Valeria; Luebbert, Michael; Maciejewski, Jaroslaw; Machherndl-Spandl, Sigrid; Magalhaes, Silvia Mm; Pfeilstoecker, Michael; Sekeres, Mikkael A.; Sperr, Wolfgang R.; Stauder, Reinhard; Tauro, Sudhir; Valent, Peter; Vallespi, Teresa; van de Loosdrecht, Arjan A.; Germing, Ulrich; Haase, Detlef; Greenberg, Peter L.

doi: 0.1371/journal.pone.0202926. eCollection 2018.

The modular network structure of the mutational landscape of Acute Myeloid Leukemia

Ibanez, Mariam; Carbonell-Caballero, Jose; Such, Esperanza; Garcia-Alonso, Luz; Liguori, Alessandro; Lopez-Pavia, Maria; Llop, Marta; Alonso, Carmen; Barragan, Eva; Gomez-Segui, Ines; Neef, Alexander; Hervas, David; Montesinos, Pau; Sanz, Guillermo; Angel Sanz, Miguel; Dopazo, Joaquin; Cervera, Jose

doi: 10.1038/s41375-018-0236-4

Correction: NG2 antigen is involved in leukemia invasiveness and central nervous system infiltration in MLL-rearranged infant B-ALL

Prieto C, López-Millán B, Roca-Ho H, Stam RW, Romero-Moya D, Rodríguez-Baena FJ, Sanjuan-Pla A, Ayllón V, Ramírez M, Bardini M, De Lorenzo P, Valsecchi MG, Stanulla M, Iglesias M, Ballerini P, Carcaboso ÁM, Mora J, Locatelli F, Bertaina A, Padilla L, Rodríguez-Manzaneque JC, Bueno C, Menéndez P